The main focus of her group is to investigate the key factors impacting the immunogenicity of radiotherapy in brain malignancies. More specifically, the Vanpouille-Box lab aims at exploring the immune-metabolic role of radiation therapy and to define the impact of TGF-beta and activin A in the radiation response of glioblastomas. With a better understanding of the metabolic changes, molecular pathways and cellular responses from the host and/or the tumor that result from radiation therapy, our main goal is to identify new actionable targets for the modulation of anti-tumor immune responses against glioblastomas.
Here are the faculty members in the Radiation Oncology department who have an interest in this research area. View all faculty with an interest in this area.