Haka, Abigail Susan

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selected publications

High-density lipoprotein or cyclodextrin extraction of cholesterol from aggregated LDL reduces foam cell formation. Journal of cell science. 2019 Academic Article GET IT
Times cited: 12
TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates. Arteriosclerosis, thrombosis, and vascular biology. 2019 Academic Article GET IT
Times cited: 48
Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and Catabolism. Arteriosclerosis, thrombosis, and vascular biology. 2019 Academic Article GET IT
Times cited: 23
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. Cell reports. 2017 Academic Article GET IT
Times cited: 198
A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux. ACS nano. 2017 Academic Article GET IT
Times cited: 87
Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism. Journal of lipid research. 2017 Academic Article GET IT
Times cited: 17
Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation. Journal of lipid research. 2016 Academic Article GET IT
Times cited: 92
Noninvasive Detection of Inflammatory Changes in White Adipose Tissue by Label-Free Raman Spectroscopy. Analytical chemistry. 2016 Academic Article GET IT
Times cited: 19
Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse. Journal of cell science. 2016 Academic Article GET IT
Times cited: 29
Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation. Arteriosclerosis, thrombosis, and vascular biology. 2015 Academic Article GET IT
Times cited: 26
Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2014 Academic Article GET IT
Times cited: 28
Identification of spermatogenesis in a rat sertoli-cell only model using Raman spectroscopy: a feasibility study. The Journal of urology. 2014 Academic Article GET IT
Times cited: 6
Sphingosine kinases are not required for inflammatory responses in macrophages. The Journal of biological chemistry. 2013 Academic Article GET IT
Times cited: 61
Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein. Arteriosclerosis, thrombosis, and vascular biology. 2013 Academic Article GET IT
Times cited: 13
Intrinsic versus laser-induced fluorescence spectroscopy for coronary atherosclerosis: a generational comparison model for testing diagnostic accuracy. Applied spectroscopy. 2012 Academic Article GET IT
Times cited: 3
Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy. PloS one. 2012 Academic Article GET IT
Times cited: 20
Mechanism of ceroid formation in atherosclerotic plaque: in situ studies using a combination of Raman and fluorescence spectroscopy. Journal of biomedical optics. 2011 Academic Article GET IT
Times cited: 30
Detection of coronary atherosclerotic plaques with superficial proteoglycans and foam cells using real-time intrinsic fluorescence spectroscopy. Atherosclerosis. 2010 Academic Article GET IT
Times cited: 13
Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins. Molecular biology of the cell. 2009 Academic Article GET IT
Times cited: 99
Diagnosing breast cancer using Raman spectroscopy: prospective analysis. Journal of biomedical optics. 2009 Academic Article GET IT
Times cited: 174
Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization. Arteriosclerosis, thrombosis, and vascular biology. 2009 Academic Article GET IT
Times cited: 39
Diagnosing breast cancer using diffuse reflectance spectroscopy and intrinsic fluorescence spectroscopy. Journal of biomedical optics. 2008 Academic Article GET IT
Times cited: 150
Determination of uncertainty in parameters extracted from single spectroscopic measurements. Journal of biomedical optics. 2007 Academic Article GET IT
Times cited: 29
Intrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion. Arteriosclerosis, thrombosis, and vascular biology. 2006 Academic Article GET IT
Times cited: 29
In vivo margin assessment during partial mastectomy breast surgery using raman spectroscopy. Cancer research. 2006 Academic Article GET IT
Times cited: 350
In vivo Raman spectral pathology of human atherosclerosis and vulnerable plaque. Journal of biomedical optics. 2006 Academic Article GET IT
Times cited: 126
Diagnosing breast cancer by using Raman spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 599
Real-time Raman system for in vivo disease diagnosis. Journal of biomedical optics. 2005 Academic Article GET IT
Times cited: 119
Classification of Fourier transform infrared microscopic imaging data of human breast cells by cluster analysis and artificial neural networks. Applied spectroscopy. 2003 Academic Article GET IT
Identifying microcalcifications in benign and malignant breast lesions by probing differences in their chemical composition using Raman spectroscopy. Cancer research. 2002 Academic Article GET IT
Times cited: 257
Model-based biological Raman spectral imaging. Journal of cellular biochemistry. Supplement. 2002 Academic Article GET IT
Times cited: 92

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Background

education and training

Ph.D., Massachusetts Institute of Technology 2005
A.B., Bryn Mawr College 1998

Contact

full name

Abigail Susan Haka

primary email

abh2005@med.cornell.edu

VIVO Weill Cornell Medical College

Abigail Susan Haka Adjunct Assistant Professor of Research in Biochemistry

Publications

selected publications

Background

education and training

Contact

full name

primary email