selected publications
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Daraxonrasib, a pan-RAS inhibitor, selectively inhibits osteosarcomas with activated KRAS by halting AKT signaling and matrix metalloprotease activity.
PloS one.
2025
Academic Article
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Times cited: 1 -
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.
Proceedings of the National Academy of Sciences of the United States of America.
2025
Academic Article
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Times cited: 1 - Selective targeting of oncogenic KRAS G12D using peptide nucleic acid oligomers attached to cell-penetrating peptides. 2025 GET IT
- IMPlications of IMP2 in RNA Biology and Disease. International journal of molecular sciences. 2025 Review GET IT
- Effects of N361 Glycosylation on Epidermal Growth Factor Receptor Biological Function. 2024 GET IT
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Cadherin-17 as a target for the immunoPET of adenocarcinoma.
European journal of nuclear medicine and molecular imaging.
2024
Academic Article
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Times cited: 3 -
KRAS: Biology, Inhibition, and Mechanisms of Inhibitor Resistance.
Current oncology (Toronto, Ont.).
2024
Review
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Times cited: 16 -
Targeting cancer's sweet spot: UGP2 as a therapeutic vulnerability.
Molecular & cellular oncology.
2021
Academic Article
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Times cited: 7 -
UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.
Proceedings of the National Academy of Sciences of the United States of America.
2021
Academic Article
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Times cited: 36 -
NOTCH and EZH2 collaborate to repress PTEN expression in breast cancer.
Communications biology.
2021
Academic Article
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Times cited: 28 -
NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy.
Cancers.
2021
Academic Article
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Times cited: 15 -
Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity.
Immunity.
2017
Academic Article
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Times cited: 52 -
Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia.
Science signaling.
2014
Academic Article
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Times cited: 41 -
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Nature.
2014
Academic Article
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Times cited: 509 -
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma.
Cell.
2011
Academic Article
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Times cited: 151 -
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma.
The Journal of experimental medicine.
2011
Academic Article
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Times cited: 101 -
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Nature genetics.
2011
Academic Article
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Times cited: 238 -
Mouse models of cancer as biological filters for complex genomic data.
Disease models & mechanisms.
2010
Academic Article
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Times cited: 6 -
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia.
Nature cell biology.
2010
Academic Article
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Times cited: 312