selected publications
- Rituximab and lenalidomide for the treatment of relapsed or refractory indolent non-Hodgkin lymphoma: real-life experience. Haematologica. 2024 Academic Article GET IT
- CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis-driven alternative splicing of PKM supports antitumor immunity. Cellular & molecular immunology. 2024 Academic Article GET IT
- Retrospective characterization of nodal marginal zone lymphoma. Blood advances. 2023 Review GET IT
- TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy. Blood advances. 2023 Academic Article GET IT
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D-2HG comes out of its shell: Metabolic effects on the immune environment.
Molecular cell.
2022
Academic Article
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Times cited: 1 - Mitonuclear genotype remodels the metabolic and microenvironmental landscape of Hürthle cell carcinoma. Science advances. 2022 Academic Article GET IT
- GCN2 kinase activation by ATP-competitive kinase inhibitors. Nature chemical biology. 2021 Academic Article GET IT
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Phase II Trial of Pembrolizumab Plus Gemcitabine, Vinorelbine, and Liposomal Doxorubicin as Second-Line Therapy for Relapsed or Refractory Classical Hodgkin Lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2021
Academic Article
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Times cited: 122 - In vivo library screening identifies the metabolic enzyme aldolase A as a promoter of metastatic lung colonization. iScience. 2021 Academic Article GET IT
- Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics. Journal of proteome research. 2021 Academic Article GET IT
- OncoTree: A Cancer Classification System for Precision Oncology. JCO clinical cancer informatics. 2021 Academic Article GET IT
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FXR mediates T cell-intrinsic responses to reduced feeding during infection.
Proceedings of the National Academy of Sciences of the United States of America.
2020
Academic Article
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Times cited: 22 -
The epigenomics of sarcoma.
Nature reviews. Cancer.
2020
Information Resource
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Times cited: 141 -
Specific patterns of H3K79 methylation influence genetic interaction of oncogenes in AML.
Blood advances.
2020
Academic Article
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Times cited: 3 -
Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction.
Cancer research.
2020
Academic Article
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Times cited: 10 -
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.
Nature.
2019
Academic Article
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Times cited: 155 -
Using genomic data for selecting the treatment of lymphoma patients.
Current opinion in hematology.
2019
Information Resource
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Times cited: 2 -
Metabolic signatures of cancer cells and stem cells.
Nature metabolism.
2019
Information Resource
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Times cited: 225 -
Integrated DNA/RNA targeted genomic profiling of diffuse large B-cell lymphoma using a clinical assay.
Blood cancer journal.
2018
Academic Article
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Times cited: 28 -
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
The Journal of clinical investigation.
2018
Academic Article
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Times cited: 60 -
As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid.
Cell metabolism.
2018
Academic Article
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Times cited: 227 -
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
Cancer discovery.
2017
Academic Article
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Times cited: 99 -
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH.
Nature chemical biology.
2017
Academic Article
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Times cited: 189 -
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Cancer discovery.
2017
Academic Article
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Times cited: 99 -
The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.
Cancer cell.
2016
Academic Article
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Times cited: 195 -
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting.
Blood.
2016
Academic Article
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Times cited: 251 -
Hypoxia Induces Production of L-2-Hydroxyglutarate.
Cell metabolism.
2015
Academic Article
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Times cited: 377 -
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
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Times cited: 244 -
Precision therapy for lymphoma--current state and future directions.
Nature reviews. Clinical oncology.
2014
Information Resource
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Times cited: 58 -
Induction of sarcomas by mutant IDH2.
Genes & development.
2013
Academic Article
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Times cited: 135 - A case of advanced gastric cancer. 2012 GET IT
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Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.
Nature immunology.
2011
Academic Article
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Times cited: 395 -
Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
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Times cited: 16 -
Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
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Times cited: 322 -
A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.
Immunity.
2009
Academic Article
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Times cited: 382 -
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.
Genes & development.
2009
Academic Article
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Times cited: 144 -
Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.
Science (New York, N.Y.).
2008
Academic Article
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Times cited: 327 -
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.
The Journal of experimental medicine.
2007
Academic Article
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Times cited: 230 -
Asymmetric T lymphocyte division in the initiation of adaptive immune responses.
Science (New York, N.Y.).
2007
Academic Article
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Times cited: 601 -
Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells.
Journal of immunology (Baltimore, Md. : 1950).
2007
Academic Article
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Times cited: 49 -
Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation.
The Journal of experimental medicine.
2007
Academic Article
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Times cited: 62 -
Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation.
Journal of immunology (Baltimore, Md. : 1950).
2006
Academic Article
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Times cited: 246 -
Not-so-great expectations: re-assessing the essence of T-cell memory.
Immunological reviews.
2006
Information Resource
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Times cited: 21 -
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.
Nature immunology.
2005
Academic Article
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Times cited: 813