Raj, Ashish

Publications

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selected publications

Selective vulnerability and resilience to Alzheimer's disease tauopathy as a function of genes and the connectome. Brain : a journal of neurology. 2025 Academic Article GET IT
Back to the Future: Predicting Individual Tau Progression in Alzheimer's Disease. 2025 GET IT
Modelling pathological spread through the structural connectome in the frontotemporal dementia clinical spectrum. Brain : a journal of neurology. 2025 Academic Article GET IT
Key Connectomes and Synaptic-Compartment-Specific Risk Genes Drive Pathological α-Synuclein Spreading. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2025 Academic Article GET IT
Directionality bias underpins divergent spatiotemporal progression of Alzheimer-related tauopathy in mouse models. Alzheimer's & Dementia. 2025 Academic Article GET IT
Mapping global brain reconfigurations following local targeted manipulations. Proceedings of the National Academy of Sciences of the United States of America. 2025 Academic Article GET IT
Times cited: 1
Structured noise champagne: an empirical Bayesian algorithm for electromagnetic brain imaging with structured noise. Frontiers in human neuroscience. 2025 Academic Article GET IT
A network-level transport model of tau progression in the Alzheimer's brain. Mathematical medicine and biology : a journal of the IMA. 2025 Academic Article GET IT
Understanding the complex interplay between tau, amyloid and the network in the spatiotemporal progression of Alzheimer's disease. Progress in neurobiology. 2025 Academic Article GET IT
Times cited: 1
Distinguish risk genes functioning at presynaptic or postsynaptic regions and key connectomes associated with pathological α-synuclein spreading. 2025 GET IT
Searching for the cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer's disease. Communications biology. 2025 Academic Article GET IT
Times cited: 1
Contributions of connectional pathways to shaping Alzheimer's disease pathologies. Brain communications. 2025 Academic Article GET IT
Spectral graph model for fMRI: A biophysical, connectivity-based generative model for the analysis of frequency-resolved resting-state fMRI. Imaging neuroscience (Cambridge, Mass.). 2024 Academic Article GET IT
Bayesian inference of frequency-specific functional connectivity in MEG imaging using a spectral graph model. Imaging neuroscience (Cambridge, Mass.). 2024 Academic Article GET IT
Beyond the Buzz: Cortical and subcortical brain changes in patients with pulsatile tinnitus. NeuroImage. Clinical. 2024 Academic Article GET IT
Integrative, segregative, and degenerate harmonics of the structural connectome. Communications biology. 2024 Academic Article GET IT
Times cited: 2
Simulation-based inference of developmental EEG maturation with the spectral graph model. Communications physics. 2024 Academic Article GET IT
Times cited: 1
Understanding the complex interplay between tau, amyloid and the network in the spatiotemporal progression of Alzheimer's Disease. 2024 GET IT
Simulation-based Inference of Developmental EEG Maturation with the Spectral Graph Model. 2024 GET IT
Directionality bias underpins divergent spatiotemporal progression of Alzheimer-related tauopathy in mouse models. 2024 GET IT
Spectral graph model for fMRI: a biophysical, connectivity-based generative model for the analysis of frequency-resolved resting state fMRI. 2024 GET IT
Impaired long-range excitatory time scale predicts abnormal neural oscillations and cognitive deficits in Alzheimer's disease. Alzheimer's research & therapy. 2024 Academic Article GET IT
Times cited: 1
Selective vulnerability and resilience to Alzheimer's disease tauopathy as a function of genes and the connectome. 2024 GET IT
Cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer's disease. 2023 GET IT
Cortical Synchrony and Information Flow during Transition from Wakefulness to Light Non-Rapid Eye Movement Sleep. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023 Academic Article GET IT
Times cited: 3
Impaired long-range excitatory time scale predicts abnormal neural oscillations and cognitive deficits in Alzheimer's disease. 2023 GET IT
Spatial cell-type enrichment predicts mouse brain connectivity. Cell reports. 2023 Academic Article GET IT
Times cited: 2
Dynamic functional connectivity MEG features of Alzheimer's disease. NeuroImage. 2023 Academic Article GET IT
Times cited: 5
Bayesian inference of a spectral graph model for brain oscillations. NeuroImage. 2023 Academic Article GET IT
Times cited: 6
Choroid Plexus Calcification Correlates with Cortical Microglial Activation in Humans: A Multimodal PET, CT, MRI Study. AJNR. American journal of neuroradiology. 2023 Academic Article GET IT
Times cited: 9
Bayesian Inference of a Spectral Graph Model for Brain Oscillations. 2023 GET IT
A joint subspace mapping between structural and functional brain connectomes. NeuroImage. 2023 Academic Article GET IT
Times cited: 7
Stability and dynamics of a spectral graph model of brain oscillations. Network neuroscience (Cambridge, Mass.). 2023 Academic Article GET IT
Times cited: 3
The effects of microglia on tauopathy progression can be quantified using Nexopathy in silico (Nexis) models. Scientific reports. 2022 Academic Article GET IT
Times cited: 11
Editorial: Advances in brain functional and structural networks modeling via graph theory. Frontiers in neuroscience. 2022 Editorial Article GET IT
Structure-function models of temporal, spatial, and spectral characteristics of non-invasive whole brain functional imaging. Frontiers in neuroscience. 2022 Review GET IT
Times cited: 3
Connectome-based biophysics models of Alzheimer's disease diagnosis and prognosis. Translational research : the journal of laboratory and clinical medicine. 2022 Review GET IT
Times cited: 7
Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer's disease. eLife. 2022 Academic Article GET IT
Times cited: 64
High activity and high functional connectivity are mutually exclusive in resting state zebrafish and human brains. BMC biology. 2022 Academic Article GET IT
Times cited: 5
Matrix Inversion and Subset Selection (MISS): A pipeline for mapping of diverse cell types across the murine brain. Proceedings of the National Academy of Sciences of the United States of America. 2022 Academic Article GET IT
Times cited: 4
Time-varying dynamic network model for dynamic resting state functional connectivity in fMRI and MEG imaging. NeuroImage. 2022 Academic Article GET IT
Times cited: 18
Predicting Functional Connectivity From Observed and Latent Structural Connectivity via Eigenvalue Mapping. Frontiers in neuroscience. 2022 Academic Article GET IT
Times cited: 3
Modeling seeding and neuroanatomic spread of pathology in amyotrophic lateral sclerosis. NeuroImage. 2022 Academic Article GET IT
Times cited: 16
Spectral graph theory of brain oscillations--Revisited and improved. NeuroImage. 2022 Academic Article GET IT
Times cited: 22
Emergence of directional bias in tau deposition from axonal transport dynamics. PLoS computational biology. 2021 Academic Article GET IT
Times cited: 10
Combined Model of Aggregation and Network Diffusion Recapitulates Alzheimer's Regional Tau-Positron Emission Tomography. Brain connectivity. 2021 Academic Article GET IT
Times cited: 16
Network-constrained technique to characterize pathology progression rate in Alzheimer's disease. Brain communications. 2021 Academic Article GET IT
Times cited: 4
Graph Models of Pathology Spread in Alzheimer's Disease: An Alternative to Conventional Graph Theoretic Analysis. Brain connectivity. 2021 Review GET IT
Times cited: 15
Emergence of canonical functional networks from the structural connectome. NeuroImage. 2021 Academic Article GET IT
Times cited: 19
Population-based input function for TSPO quantification and kinetic modeling with [¹¹C]-DPA-713. EJNMMI physics. 2021 Academic Article GET IT
Computational Models in Electroencephalography. Brain topography. 2021 Review GET IT
Times cited: 34
Network model of pathology spread recapitulates neurodegeneration and selective vulnerability in Huntington's Disease. NeuroImage. 2021 Academic Article GET IT
Times cited: 15
Algebraic relationship between the structural network's Laplacian and functional network's adjacency matrix is preserved in temporal lobe epilepsy subjects. NeuroImage. 2020 Academic Article GET IT
Times cited: 7
Molecular Imaging of Striatal Dopaminergic Neuronal Loss and the Neurovascular Unit in Parkinson Disease. Frontiers in neuroscience. 2020 Academic Article GET IT
Times cited: 11
A dictionary-based graph-cut algorithm for MRI reconstruction. NMR in biomedicine. 2020 Academic Article GET IT
Origins of atrophy in Parkinson linked to early onset and local transcription patterns. Brain communications. 2020 Academic Article GET IT
Times cited: 6
Network mediation of pathology pattern in sporadic Creutzfeldt-Jakob disease. Brain communications. 2020 Academic Article GET IT
Times cited: 5
Spectral graph theory of brain oscillations. Human brain mapping. 2020 Academic Article GET IT
Times cited: 39
Stereotaxic Diffusion Tensor Imaging White Matter Atlas for the in vivo Domestic Feline Brain. Frontiers in neuroanatomy. 2020 Academic Article GET IT
Times cited: 4
Dynamical Role of Pivotal Brain Regions in Parkinson Symptomatology Uncovered with Deep Learning. Brain sciences. 2020 Academic Article GET IT
Times cited: 8
Neural connectivity predicts spreading of alpha-synuclein pathology in fibril-injected mouse models: Involvement of retrograde and anterograde axonal propagation. Neurobiology of disease. 2019 Academic Article GET IT
Times cited: 64
Regional transcriptional architecture of Parkinson's disease pathogenesis and network spread. Brain : a journal of neurology. 2019 Academic Article GET IT
Times cited: 11
Longitudinal increases in structural connectome segregation and functional connectome integration are associated with better recovery after mild TBI. Human brain mapping. 2019 Academic Article GET IT
Times cited: 36
Systematic Differences Between Perceptually Relevant Image Statistics of Brain MRI and Natural Images. Frontiers in neuroinformatics. 2019 Academic Article GET IT
Times cited: 7
Slow-gamma frequencies are optimally guarded against effects of neurodegenerative diseases and traumatic brain injuries. Journal of computational neuroscience. 2019 Academic Article GET IT
Times cited: 4
Predictive model of spread of Parkinson's pathology using network diffusion. NeuroImage. 2019 Academic Article GET IT
Times cited: 59
Normal diffusivity of the domestic feline brain. The Journal of comparative neurology. 2018 Academic Article GET IT
Times cited: 1
Models of Network Spread and Network Degeneration in Brain Disorders. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2018 Information Resource GET IT
Times cited: 55
A method for inferring regional origins of neurodegeneration. Brain : a journal of neurology. 2018 Academic Article GET IT
Times cited: 35
Functional brain connectivity is predictable from anatomic network's Laplacian eigen-structure. NeuroImage. 2018 Academic Article GET IT
Times cited: 104
Regional expression of genes mediating trans-synaptic alpha-synuclein transfer predicts regional atrophy in Parkinson disease. NeuroImage. Clinical. 2018 Academic Article GET IT
Times cited: 40
Regional vulnerability in Alzheimer's disease: The role of cell-autonomous and transneuronal processes. Alzheimer's & Dementia. 2018 Academic Article GET IT
Times cited: 22
Preserved Structural Network Organization Mediates Pathology Spread in Alzheimer's Disease Spectrum Despite Loss of White Matter Tract Integrity. Journal of Alzheimer's disease : JAD. 2018 Academic Article GET IT
Times cited: 19
Predictive Model of Spread of Progressive Supranuclear Palsy Using Directional Network Diffusion. Frontiers in neurology. 2017 Academic Article GET IT
Times cited: 33
Analysis of Amyloid-β Pathology Spread in Mouse Models Suggests Spread Is Driven by Spatial Proximity, Not Connectivity. Frontiers in neurology. 2017 Academic Article GET IT
Times cited: 17
Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia. Brain connectivity. 2017 Academic Article GET IT
Times cited: 11
Mature Hippocampal Neurons Require LIS1 for Synaptic Integrity: Implications for Cognition. Biological psychiatry. 2017 Academic Article GET IT
Times cited: 14
Connectivity, not region-intrinsic properties, predicts regional vulnerability to progressive tau pathology in mouse models of disease. Acta neuropathologica communications. 2017 Academic Article GET IT
Times cited: 22
Brain network eigenmodes provide a robust and compact representation of the structural connectome in health and disease. PLoS computational biology. 2017 Academic Article GET IT
Times cited: 50
MRI Analysis of White Matter Myelin Water Content in Multiple Sclerosis: A Novel Approach Applied to Finding Correlates of Cortical Thinning. Frontiers in neuroscience. 2017 Academic Article GET IT
Times cited: 16
The Brain's Structural Connectome Mediates the Relationship between Regional Neuroimaging Biomarkers in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2017 Academic Article GET IT
Times cited: 9
Network Analysis on Predicting Mean Diffusivity Change at Group Level in Temporal Lobe Epilepsy. Brain connectivity. 2016 Academic Article GET IT
The application of a mathematical model linking structural and functional connectomes in severe brain injury. NeuroImage. Clinical. 2016 Academic Article GET IT
Times cited: 39
Structural connectome disruption at baseline predicts 6-months post-stroke outcome. Human brain mapping. 2016 Academic Article GET IT
Times cited: 76
Profilometry: A new statistical framework for the characterization of white matter pathways, with application to multiple sclerosis. Human brain mapping. 2015 Academic Article GET IT
Times cited: 33
Relating Cortical Atrophy in Temporal Lobe Epilepsy with Graph Diffusion-Based Network Models. PLoS computational biology. 2015 Academic Article GET IT
Times cited: 20
Measuring longitudinal myelin water fraction in new multiple sclerosis lesions. NeuroImage. Clinical. 2015 Academic Article GET IT
Times cited: 63
Feasibility and reproducibility of whole brain myelin water mapping in 4 minutes using fast acquisition with spiral trajectory and adiabatic T2prep (FAST-T2) at 3T. Magnetic resonance in medicine. 2015 Academic Article GET IT
Times cited: 56
Exploring the brain's structural connectome: A quantitative stroke lesion-dysfunction mapping study. Human brain mapping. 2015 Academic Article GET IT
Times cited: 43
Network Diffusion Model of Progression Predicts Longitudinal Patterns of Atrophy and Metabolism in Alzheimer's Disease. Cell reports. 2015 Academic Article GET IT
Times cited: 160
Simultaneous phase unwrapping and removal of chemical shift (SPURS) using graph cuts: application in quantitative susceptibility mapping. IEEE transactions on medical imaging. 2014 Academic Article GET IT
Times cited: 54
Widespread white matter degeneration preceding the onset of dementia. Alzheimer's & Dementia. 2014 Academic Article GET IT
Times cited: 75
Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter. NeuroImage. 2014 Academic Article GET IT
Times cited: 22
Multi-compartment T2 relaxometry using a spatially constrained multi-Gaussian model. PloS one. 2014 Academic Article GET IT
Times cited: 49
Spatial patterns of genome-wide expression profiles reflect anatomic and fiber connectivity architecture of healthy human brain. Human brain mapping. 2014 Academic Article GET IT
Times cited: 39
Predicting future brain tissue loss from white matter connectivity disruption in ischemic stroke. Stroke. 2014 Academic Article GET IT
Times cited: 38
Network diffusion accurately models the relationship between structural and functional brain connectivity networks. NeuroImage. 2013 Academic Article GET IT
Times cited: 197
Discriminative random field segmentation of lung nodules in CT studies. Computational and mathematical methods in medicine. 2013 Academic Article GET IT
Times cited: 1
Effects of increased image noise on image quality and quantitative interpretation in brain CT perfusion. AJNR. American journal of neuroradiology. 2013 Academic Article GET IT
Times cited: 23
The Network Modification (NeMo) Tool: elucidating the effect of white matter integrity changes on cortical and subcortical structural connectivity. Brain connectivity. 2013 Academic Article GET IT
Times cited: 97
Differential diagnosis of normal pressure hydrocephalus by MRI mean diffusivity histogram analysis. AJNR. American journal of neuroradiology. 2012 Academic Article GET IT
Times cited: 31
Comparing new templates and atlas-based segmentations in the volumetric analysis of brain magnetic resonance images for diagnosing Alzheimer's disease. Alzheimer's & Dementia. 2012 Academic Article GET IT
Times cited: 12
Loss in connectivity among regions of the brain reward system in alcohol dependence. Human brain mapping. 2012 Academic Article GET IT
Times cited: 24
Statistics of weighted brain networks reveal hierarchical organization and Gaussian degree distribution. PloS one. 2012 Academic Article GET IT
Times cited: 20
A network diffusion model of disease progression in dementia. Neuron. 2012 Academic Article GET IT
Times cited: 540
Linking white matter integrity loss to associated cortical regions using structural connectivity information in Alzheimer's disease and fronto-temporal dementia: the Loss in Connectivity (LoCo) score. NeuroImage. 2012 Academic Article GET IT
Times cited: 25
Bayesian algorithm using spatial priors for multiexponential T₂ relaxometry from multiecho spin echo MRI. Magnetic resonance in medicine. 2012 Academic Article GET IT
Times cited: 43
T2 prep three-dimensional spiral imaging with efficient whole brain coverage for myelin water quantification at 1.5 tesla. Magnetic resonance in medicine. 2012 Academic Article GET IT
Times cited: 46
The wiring economy principle: connectivity determines anatomy in the human brain. PloS one. 2011 Academic Article GET IT
Times cited: 65
A pilot study of quantitative MRI measurements of ventricular volume and cortical atrophy for the differential diagnosis of normal pressure hydrocephalus. Neurology research international. 2011 Academic Article GET IT
Times cited: 45
Volumetric and visual rating of magnetic resonance imaging scans in the diagnosis of amnestic mild cognitive impairment and Alzheimer's disease. Alzheimer's & Dementia. 2011 Academic Article GET IT
Times cited: 56
The generation and validation of white matter connectivity importance maps. NeuroImage. 2011 Academic Article GET IT
Times cited: 33
A fast Edge-preserving Bayesian reconstruction method for Parallel Imaging applications in cardiac MRI. Magnetic resonance in medicine. 2011 Academic Article GET IT
Times cited: 4
Spatial HARDI: improved visualization of complex white matter architecture with Bayesian spatial regularization. NeuroImage. 2010 Academic Article GET IT
Times cited: 22
Network-level analysis of cortical thickness of the epileptic brain. NeuroImage. 2010 Academic Article GET IT
Times cited: 77
Association of white matter hyperintensity measurements on brain MR imaging with cognitive status, medial temporal atrophy, and cardiovascular risk factors. AJNR. American journal of neuroradiology. 2009 Academic Article GET IT
Times cited: 41
Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease. Neurology. 2008 Academic Article GET IT
Times cited: 224
A maximum likelihood approach to parallel imaging with coil sensitivity noise. IEEE transactions on medical imaging. 2007 Academic Article GET IT
Fast and stable bayesian image expansion using sparse edge priors. IEEE transactions on image processing : a publication of the IEEE Signal Processing Society. 2007 Academic Article GET IT
Times cited: 4
Bayesian parallel imaging with edge-preserving priors. Magnetic resonance in medicine. 2007 Academic Article GET IT
Times cited: 59
Automatic algorithm for correcting motion artifacts in time-resolved two-dimensional magnetic resonance angiography using convex projections. Magnetic resonance in medicine. 2006 Academic Article GET IT
Times cited: 3

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Research

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missing activity Co-Principal Investigator 2016 - 2023

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Background

education and training

Ph.D., Cornell University 2005
M.S., Cornell University 2001
B.E., University of Auckland (New Zealand) 1998

Contact

full name

Ashish Raj

primary email

asr2004@med.cornell.edu

VIVO Weill Cornell Medical College

Ashish Raj Adjunct Professor of Computer Science in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email