selected publications
- Epinephrine inhibits PI3Kα via the Hippo kinases. Cell reports. 2023 Academic Article GET IT
- Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice. Cell reports. 2022 Academic Article GET IT
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Acyl-Coenzyme A Thioesterase 9 Traffics Mitochondrial Short-Chain Fatty Acids Toward De Novo Lipogenesis and Glucose Production in the Liver.
Hepatology (Baltimore, Md.).
2020
Academic Article
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Times cited: 4 -
Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease.
Metabolites.
2020
Review
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Times cited: 31 -
Fatty acid activation in thermogenic adipose tissue.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2018
Review
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Times cited: 30 -
Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity.
Nature genetics.
2018
Letter
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Times cited: 161 -
Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 28 -
Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization.
Molecular and cellular biology.
2014
Academic Article
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Times cited: 27 -
Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling.
Science signaling.
2013
Academic Article
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Times cited: 25 -
Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR.
Nature chemical biology.
2012
Academic Article
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Times cited: 53 -
Bariatric surgery in a patient with complete MC4R deficiency.
2010
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Times cited: 60 -
Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus.
Clinical endocrinology.
2008
Academic Article
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Times cited: 32 -
Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study.
Human molecular genetics.
2008
Academic Article
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Times cited: 109 -
Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain.
Pediatric research.
2008
Academic Article
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Times cited: 57 -
Medical sequencing at the extremes of human body mass.
American journal of human genetics.
2007
Academic Article
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Times cited: 182 -
Probing protein structure and dynamics by second-derivative ultraviolet absorption analysis of cation-{pi} interactions.
Protein science : a publication of the Protein Society.
2006
Academic Article
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Times cited: 63 -
Derivative absorbance spectroscopy and protein phase diagrams as tools for comprehensive protein characterization: a bGCSF case study.
Journal of pharmaceutical sciences.
2003
Academic Article
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Times cited: 120 -
Structure-function analysis of invasion plasmid antigen C (IpaC) from Shigella flexneri.
The Journal of biological chemistry.
2002
Academic Article
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Times cited: 57