Kaur, Baljit

Publications

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selected publications

Restoring Amyloid Clearance via Astrocytes: Z17 Is a Selective Inhibitor of CHI3L1 in Alzheimers Disease. 2025 GET IT
HTS-Oracle: Experimentally validated AI-enabled prioritization for generalizable small molecule hit discovery. 2025 GET IT
Virtual Screening-Guided Discovery of Small-Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma Spheroids. ACS medicinal chemistry letters. 2025 Academic Article GET IT
Discovery of a CHI3L1-Targeted Small Molecule Modulating Neuroinflammation in Alzheimer's Disease via DNA-Encoded Library (DEL) Screening ^†. 2025 GET IT
Affinity Selection-Mass spectrometry coupled with biophysical validation enables proof-of-concept discovery of CHI3L1 binders. Biochemical and biophysical research communications. 2025 Academic Article GET IT
Affinity Selection-Mass Spectrometry Coupled with Biophysical Validation Enables Proof-of-Concept Discovery of CHI3L1 Binders. 2025 GET IT
Structure-Based Virtual Screening Identifies TREM2-Targeted Small Molecules that Enhance Microglial Phagocytosis. 2025 GET IT
Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy. 2025 GET IT
Virtual Screening-Guided Discovery of Small Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma Spheroids. 2025 GET IT
TREM2 and LAG-3 in cancer and Alzheimer's disease immunotherapy. Trends in pharmacological sciences. 2025 Review GET IT
CHI3L1-targeted small molecules as glioblastoma therapies: Virtual screening-based discovery, biophysical validation, pharmacokinetic profiling, and evaluation in glioblastoma spheroids. European journal of medicinal chemistry. 2025 Academic Article GET IT
Lead optimization of a CHI3L1 inhibitor for Glioblastoma: Enhanced target engagement, pharmacokinetics, and efficacy in 3D spheroid models. European journal of medicinal chemistry. 2025 Academic Article GET IT
CD28 and ICOS in immune regulation: Structural insights and therapeutic targeting. Bioorganic & medicinal chemistry letters. 2025 Review GET IT
CHI3L1-Targeted Small Molecules as Glioblastoma Therapies: Virtual Screening-Based Discovery, Biophysical Validation, Pharmacokinetic Profiling, and Evaluation in Glioblastoma Spheroids. 2025 GET IT
Biological and therapeutic significance of targeting NLRP3 inflammasome in the brain and the current efforts to develop brain-penetrant inhibitors. Advances in pharmacology (San Diego, Calif.). 2024 Review GET IT
Times cited: 5
Retraction notice to "Thermostable xylanases from thermophilic fungi and bacteria: Current perspective" [Bioresour. Technol. 277 (2019) 195-203]. Bioresource technology. 2024 Academic Article GET IT
Functional Characterization of an Arylsulfonamide-Based Small-Molecule Inhibitor of the NLRP3 Inflammasome. ACS chemical neuroscience. 2024 Academic Article GET IT
Times cited: 1
Developing endophytic Penicillium oxalicum as a source of lignocellulolytic enzymes for enhanced hydrolysis of biorefinery relevant pretreated rice straw. Bioprocess and biosystems engineering. 2024 Academic Article GET IT
Times cited: 1
Genome and secretome insights: unravelling the lignocellulolytic potential of Myceliophthora verrucosa for enhanced hydrolysis of lignocellulosic biomass. Archives of microbiology. 2024 Academic Article GET IT
Times cited: 6
Small Peptides Targeting BACE-1, AChE, and A-β Reversing Scopolamine-Induced Memory Impairment: A Multitarget Approach against Alzheimer's Disease. ACS omega. 2024 Academic Article GET IT
Times cited: 2
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Journal of medicinal chemistry. 2023 Academic Article GET IT
Times cited: 11
A patent review of NLRP3 inhibitors to treat autoimmune diseases. Expert opinion on therapeutic patents. 2023 Review GET IT
Times cited: 11
Alzheimer's Disease: Treatment of Multi-Factorial Disorders with Multi- Target Approach. Mini reviews in medicinal chemistry. 2023 Academic Article GET IT
Times cited: 3
Proline based rationally designed peptide esters against dipeptidyl peptidase-4: Highly potent anti-diabetic agents. Bioorganic & medicinal chemistry letters. 2022 Academic Article GET IT
Times cited: 4
Lignocellulolytic enzymes from Aspergillus allahabadii for efficient bioconversion of rice straw into fermentable sugars and biogas. Bioresource technology. 2022 Academic Article GET IT
Times cited: 20
Epoxides: Developability as active pharmaceutical ingredients and biochemical probes. Bioorganic chemistry. 2022 Review GET IT
Times cited: 33
Including video and novel parameter-height of penetration of external anal sphincter-in magnetic resonance imaging reporting of anal fistula. World journal of gastrointestinal surgery. 2022 Review GET IT
Combination of system biology and classical approaches for developing biorefinery relevant lignocellulolytic Rasamsonia emersonii strain. Bioresource technology. 2022 Academic Article GET IT
Times cited: 17
Inflammation: Biochemistry, cellular targets, anti-inflammatory agents and challenges with special emphasis on cyclooxygenase-2. Bioorganic chemistry. 2022 Review GET IT
Times cited: 104
Rationally designed TNF-α inhibitors: Identification of promising cytotoxic agents. Bioorganic & medicinal chemistry letters. 2021 Academic Article GET IT
Times cited: 5
Utilization of Postnatal Care among Rural Women in Punjab. Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine. 2021 Academic Article GET IT
Times cited: 3
Analysing the expenditure on childbearing: a community-based cross-sectional study in rural areas of Punjab (India). BMC health services research. 2021 Academic Article GET IT
Times cited: 4
Role of water in cyclooxygenase catalysis and design of anti-inflammatory agents targeting two sites of the enzyme. Scientific reports. 2020 Academic Article GET IT
Times cited: 1
An innovative approach of priming lignocellulosics with lytic polysaccharide mono-oxygenases prior to saccharification with glycosyl hydrolases can economize second generation ethanol process. Bioresource technology. 2020 Academic Article GET IT
Times cited: 28
Engineered Substrate for Cyclooxygenase-2: A Pentapeptide Isoconformational to Arachidonic Acid for Managing Inflammation. Journal of medicinal chemistry. 2019 Academic Article GET IT
Times cited: 10
Thermostable xylanases from thermophilic fungi and bacteria: Current perspective. Bioresource technology. 2019 Review GET IT
Times cited: 132
A bisubstrate reagent orchestrating adenosine triphosphate and l-tyrosine and making tyrosyl adenylate: partial mimicking of tyrosyl-tRNA synthetase. Organic & biomolecular chemistry. 2018 Academic Article GET IT
Times cited: 1
Tailoring the Substitution Pattern on 1,3,5-Triazine for Targeting Cyclooxygenase-2: Discovery and Structure-Activity Relationship of Triazine-4-Aminophenylmorpholin-3-one Hybrids that Reverse Algesia and Inflammation in Swiss Albino Mice. Journal of medicinal chemistry. 2018 Academic Article GET IT
Times cited: 28
Rational modification of semaxanib and sunitinib for developing a tumor growth inhibitor targeting ATP binding site of tyrosine kinase. Bioorganic & medicinal chemistry letters. 2017 Academic Article GET IT
Times cited: 23
Mycothermus thermophilus (Syn. Scytalidium thermophilum): Repertoire of a diverse array of efficient cellulases and hemicellulases in the secretome revealed. Bioresource technology. 2016 Academic Article GET IT
Times cited: 90
Evaluation of secretome of highly efficient lignocellulolytic Penicillium sp. Dal 5 isolated from rhizosphere of conifers. Bioresource technology. 2016 Academic Article GET IT
Times cited: 33
Enhanced cellulase producing mutants developed from heterokaryotic Aspergillus strain. Bioresource technology. 2014 Academic Article GET IT
Times cited: 43
Proteome-based profiling of hypercellulase-producing strains developed through interspecific protoplast fusion between Aspergillus nidulans and Aspergillus tubingensis. Applied biochemistry and biotechnology. 2012 Academic Article GET IT
Times cited: 25

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Background

education and training

Ph.D., Guru Nanak Dev University (India) 22
M.Sc., Guru Nanak Dev University (India) 2016
B.Sc., Punjab University Government Medical College, Rohtak (India) 2014

Contact

full name

Baljit Kaur

primary email

bak4011@med.cornell.edu

VIVO Weill Cornell Medical College

Baljit Kaur Postdoctoral Associate in Radiology

Publications

selected publications

Background

education and training

Contact

full name

primary email