Zhao, Baohong

Publications

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selected publications

Reciprocal suppression between TGFβ signaling and TNF stimulation finetunes the macrophage inflammatory response. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024 Academic Article GET IT
A p38 MAP kinase inhibitor suppresses osteoclastogenesis and alleviates ovariectomy-induced bone loss through the inhibition of bone turnover. Biochemical pharmacology. 2024 Academic Article GET IT
RBP-J regulates homeostasis and function of circulating Ly6C^lo monocytes. eLife. 2024 Academic Article GET IT
Long non-coding RNA Malat1 is essential for fine-tuning bone homeostasis through orchestrating cellular crosstalk and the β-catenin-OPG/Jagged1 pathway. 2023 GET IT
Optineurin regulates osteoblast function in an age-dependent fashion in a mouse model of Paget's disease of bone. Bone. 2023 Academic Article GET IT
Jagged1 Acts as an RBP-J Target and Feedback Suppresses TNF-Mediated Inflammatory Osteoclastogenesis. Journal of immunology (Baltimore, Md. : 1950). 2023 Academic Article GET IT
Epsilon toxin-producing Clostridium perfringens colonize the MS gut and epsilon toxin overcomes immune privilege. The Journal of clinical investigation. 2023 Academic Article GET IT
Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass. eLife. 2023 Academic Article GET IT
Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget's disease of bone. Science advances. 2023 Academic Article GET IT
Times cited: 14
Cytokine-mediated immunomodulation of osteoclastogenesis. Bone. 2022 Review GET IT
Times cited: 8
TGFβ reprograms TNF stimulation of macrophages towards a non-canonical pathway driving inflammatory osteoclastogenesis. Nature communications. 2022 Academic Article GET IT
RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis. 2022 GET IT
Times cited: 2
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells. eLife. 2021 Academic Article GET IT
Times cited: 42
Regulation of Osteoclastogenesis and Bone Resorption by miRNAs. Frontiers in cell and developmental biology. 2021 Review GET IT
Times cited: 21
Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis. eLife. 2020 Academic Article GET IT
Times cited: 12
Intrinsic Restriction of TNF-Mediated Inflammatory Osteoclastogenesis and Bone Resorption. Frontiers in endocrinology. 2020 Review GET IT
Times cited: 26
The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens. The Journal of experimental medicine. 2020 Academic Article GET IT
Times cited: 15
Osteoclasts are not a source of SLIT3. Bone research. 2020 Academic Article GET IT
Times cited: 26
Three paralogous clusters of the miR-17~92 family of microRNAs restrain IL-12-mediated immune defense. Cellular & molecular immunology. 2020 Academic Article GET IT
Times cited: 10
Regulatory network mediated by RBP-J/NFATc1-miR182 controls inflammatory bone resorption. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Academic Article GET IT
Times cited: 16
Osteoclastic microRNAs and their translational potential in skeletal diseases. Seminars in immunopathology. 2019 Information Resource GET IT
Times cited: 18
[An optimized method for embedding undecalcified mouse tibias in plastic blocks]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2019 Academic Article GET IT
Identification of a Novel Role for Foxo3 Isoform2 in Osteoclastic Inhibition. Journal of immunology (Baltimore, Md. : 1950). 2019 Academic Article GET IT
Times cited: 7
Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses. Immunity. 2019 Academic Article GET IT
Times cited: 32
Hes1 attenuates type I IFN responses via VEGF-C and WDFY1. The Journal of experimental medicine. 2019 Academic Article GET IT
Times cited: 15
G-protein Gα₁₃ functions as a cytoskeletal and mitochondrial regulator to restrain osteoclast function. Scientific reports. 2019 Academic Article GET IT
Times cited: 18
Lipoteichoic acid of Enterococcus faecalis inhibits osteoclastogenesis via transcription factor RBP-J. Innate immunity. 2018 Academic Article GET IT
Times cited: 13
Bone protection by inhibition of microRNA-182. Nature communications. 2018 Academic Article GET IT
Times cited: 76
Targeting skeletal endothelium to ameliorate bone loss. Nature medicine. 2018 Academic Article GET IT
Times cited: 248
Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models. Nature communications. 2018 Academic Article GET IT
Times cited: 28
Does TNF Promote or Restrain Osteoclastogenesis and Inflammatory Bone Resorption?. Critical reviews in immunology. 2018 Review GET IT
Times cited: 16
TNF and Bone Remodeling. Current osteoporosis reports. 2017 Review GET IT
Times cited: 131
Boi-ogi-to (TJ-20), a Kampo Formula, Suppresses the Inflammatory Bone Destruction and the Expression of Cytokines in the Synovia of Ankle Joints of Adjuvant Arthritic Rats. Evidence-based complementary and alternative medicine : eCAM. 2017 Academic Article GET IT
Times cited: 3
Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption. Journal of immunology (Baltimore, Md. : 1950). 2017 Academic Article GET IT
Times cited: 15
The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation. Nature immunology. 2016 Academic Article GET IT
Times cited: 66
RBP-J-Regulated miR-182 Promotes TNF-α-Induced Osteoclastogenesis. Journal of immunology (Baltimore, Md. : 1950). 2016 Academic Article GET IT
Times cited: 61
Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8. Journal of immunology (Baltimore, Md. : 1950). 2016 Academic Article GET IT
Times cited: 61
RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes. Protein & cell. 2016 Academic Article GET IT
Times cited: 37
RBP-J and ITAM crosstalk. Oncotarget. 2015 Editorial Article GET IT
Enterococcus faecalis promotes osteoclastogenesis and semaphorin 4D expression. Innate immunity. 2015 Academic Article GET IT
Times cited: 9
Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination. mBio. 2015 Academic Article GET IT
Times cited: 72
Dormancy activation mechanism of oral cavity cancer stem cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015 Academic Article GET IT
Times cited: 10
[Study of relationship between (Ca+Zn)/P of pure titanium surface coating and biological activity of osteoblasts]. Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2015 Academic Article GET IT
Times cited: 1
Biocompatibility improvement of titanium surfaces modified by plasma oxidation. Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology. 2015 Article GET IT
Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. Nature communications. 2014 Academic Article GET IT
Times cited: 111
RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis. The Journal of clinical investigation. 2014 Academic Article GET IT
Times cited: 58
[Study of relationship between different contents of zinc and antibacterial activity on calcium phosphate coating modified by plasma electrolytic oxidation method]. Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2014 Academic Article GET IT
[A clinical retrospective analysis of dental implants replaced in previously failed sites]. Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2014 Academic Article GET IT
Lack of ADAM10 in endothelial cells affects osteoclasts at the chondro-osseus junction. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2013 Academic Article GET IT
Times cited: 11
Effect of Zn content on cytoactivity and bacteriostasis of micro-arc oxidation coatings on pure titanium. Surface and Coatings Technology. 2013 Article GET IT
Porous structure preparation and wettability control on titanium implant. Surface and Coatings Technology. 2013 Article GET IT
The effect of bone formation with Bio-Oss guided by collagen membrane. Journal of Hard Tissue Biology. 2013 Article GET IT
[An assessment of different crown-to-implant ratio for implant teeth in the posterior region over 5 years]. Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2013 Academic Article GET IT
Synthetic octacalcium phosphate-enhanced reparative dentine formation via induction of odontoblast differentiation. Journal of tissue engineering and regenerative medicine. 2013 Academic Article GET IT
Times cited: 13
[The antibacterial properties of Ca and Zn-containing coatings prepared with micro-arc oxidation]. Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2012 Academic Article GET IT
Times cited: 3
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nature immunology. 2012 Academic Article GET IT
Times cited: 359
TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J. The Journal of experimental medicine. 2012 Academic Article GET IT
Times cited: 159
Histomorphometrical and clinical study of connective tissue around titanium dental implants with porous surfaces in a canine model. Journal of biomaterials applications. 2011 Academic Article GET IT
Times cited: 7
Phase transformation and corrosion properties of surface oxidized NiTi shape memory alloy. Journal of Hard Tissue Biology. 2011 Article GET IT
Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors. Arthritis research & therapy. 2011 Review GET IT
Times cited: 118
Enhancement of bone morphogenetic protein-2-induced ectopic bone formation by transforming growth factor-β1. Tissue engineering. Part A. 2010 Academic Article GET IT
Times cited: 73
Carbonic anhydrase II regulates differentiation of ameloblasts via intracellular pH-dependent JNK signaling pathway. Journal of cellular physiology. 2010 Academic Article GET IT
Times cited: 10
Bone morphogenetic protein 2 enhances mouse osteoclast differentiation via increased levels of receptor activator of NF-κB ligand expression in osteoblasts. Cell and tissue research. 2010 Academic Article GET IT
Times cited: 33
Interleukin-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of nuclear factor of activated T cells c1 and suppressing proximal RANK signaling. Arthritis and rheumatism. 2010 Academic Article GET IT
Times cited: 80
Osteoclast differentiation induced by synthetic octacalcium phosphate through receptor activator of NF-kappaB ligand expression in osteoblasts. Tissue engineering. Part A. 2009 Academic Article GET IT
Times cited: 65
Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis. Nature medicine. 2009 Academic Article GET IT
Times cited: 261
[Effect of HA/TiO2 coating titanium surface on the growth of MG63]. Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2009 Academic Article GET IT
IFN-gamma down-regulates Secretoglobin 3A1 gene expression. Biochemical and biophysical research communications. 2009 Academic Article GET IT
Times cited: 5
Comparison of biological characteristics of mesenchymal stem cells grown on two different titanium implant surfaces. Biomedical materials (Bristol, England). 2008 Academic Article GET IT
Times cited: 26
Characterization of synovial cell clones isolated from rheumatoid arthritis patients: possible involvement of TNF-alpha in reduction of osteoprotegerin in synovium. Cytokine. 2007 Academic Article GET IT
Times cited: 6
Effects of KTP laser irradiation, diode laser, and LED on tooth bleaching: a comparative study. Photomedicine and laser surgery. 2007 Academic Article GET IT
Times cited: 70
Effects of surface morphology on human osteosarcoma cell response. Current Applied Physics. 2007 Article GET IT
Interleukin-4 inhibition of osteoclast differentiation is stronger than that of interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts. Immunology. 2007 Academic Article GET IT
Times cited: 83
Micro-arc oxidation in various concentration of KOH and structural change by different cut off potential. Current Applied Physics. 2007 Article GET IT
Changes in anodized titanium surface morphology by virtue of different unipolar DC pulse waveform. Surface and Coatings Technology. 2007 Article GET IT
Industrial application of ion beam assisted deposition on medical implants. Surface and Coatings Technology. 2007 Article GET IT
Identification and characterization of the precursors committed to osteoclasts induced by TNF-related activation-induced cytokine/receptor activator of NF-kappa B ligand. Journal of immunology (Baltimore, Md. : 1950). 2006 Academic Article GET IT
Times cited: 37
Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2. The Journal of biological chemistry. 2006 Academic Article GET IT
Times cited: 233
Bone formation enhanced by implanted octacalcium phosphate involving conversion into Ca-deficient hydroxyapatite. Biomaterials. 2006 Academic Article GET IT
Times cited: 254
Characterization of micro-arc oxidized titanium. Journal Wuhan University of Technology, Materials Science Edition. 2005 Article
Influence of RGD-grafted titanium on the adhesion and spreading of human gingival fibroblasts. Cailiao Yanjiu Xuebao/Chinese Journal of Materials Research. 2005 Article
Effects of RGD peptide grafting to titanium dental implants on the adhesion of human gingival fibroblasts and epithelial cells. Current Applied Physics. 2005 Article GET IT
Effects of RGD-grafted titanium on the adhesion of human gingival fibroblasts. Cailiao Yanjiu Xuebao/Chinese Journal of Materials Research. 2005 Article
Improvement of fibroblast adherence to titanium surface by calcium phosphate coating formed with IBAD. Surface and Coatings Technology. 2005 Article GET IT
[Effects of TCP/HA-coating titanium on the adhesion behavior of human gingival fibroblasts]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2004 Academic Article GET IT
Times cited: 2
[Microcosmic analysis of TCP/HA coating with micro-pores on titanium by IBAD method.]. Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2004 Academic Article GET IT
Times cited: 3
[Human gingival epithelial cells cultured by a combined method of serum containing medium and serum free medium]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. 2004 Academic Article GET IT
[Location and negotiation of second mesiobuccal canals in maxillary molars]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2003 Academic Article GET IT
Times cited: 5
[Experimental study on effect of capping pulp with collagen]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2001 Academic Article GET IT
Times cited: 1
[The combined occluding effect of fluor protector and Nd:YAG laser irradiation on human dentinal tubules]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2001 Academic Article GET IT
Times cited: 2

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Background

education and training

Ph.D., Showa University Graduate School (Japan) 2008
D.M.D., Peking University (China) 2001
B.M., Peking University Health Science Center (China) 1999

Contact

full name

Baohong Zhao

primary email

zhaob@hss.edu

VIVO Weill Cornell Medical College

Baohong Zhao Professor of BIochemistry in Medicine

Publications

selected publications

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email