Das, Bhaskar Chandra

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selected publications

Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction. Nature communications. 2025 Academic Article GET IT
The GR-LEDGF/p75-HSP27 Axis Contributes to Cross-Resistance Between Enzalutamide and Docetaxel in Prostate Cancer. Cells. 2025 Academic Article GET IT
Chondrosarcoma: Multi-Targeting Therapeutic Effects of Doxorubicin, BEZ235, and the Small Molecule Aspartyl-Asparaginyl-β-hydroxylase Inhibitor SMI1182. Cancers. 2025 Academic Article GET IT
Inhibition of Mitochondrial-Associated Protein MAGMAS Resensitizes Chemoresistant Prostate Cancer Cells to Docetaxel. Cancers. 2025 Academic Article GET IT
Dual targeting of the mitochondrial Lon peptidase 1 and the chymotrypsin-like proteasome activity as a potential therapeutic strategy in malignant astrocytoma models. Pharmacological research. 2025 Academic Article GET IT
Times cited: 1
Methionine Aminopeptidase 2 (MetAP2) Inhibitor BL6 Attenuates Inflammation in Cultured Microglia and in a Mouse Model of Alzheimer's Disease. Molecules (Basel, Switzerland). 2025 Academic Article GET IT
Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele. 2024 GET IT
Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma. PloS one. 2024 Academic Article GET IT
Targeting Krüppel-Like Factor 2 as a Novel Therapy for Glomerular Endothelial Cell Injury in Diabetic Kidney Disease. Journal of the American Society of Nephrology : JASN. 2024 Academic Article GET IT
Times cited: 3
Methionine aminopeptidases: Potential therapeutic target for microsporidia and other microbes. The Journal of eukaryotic microbiology. 2024 Review GET IT
Times cited: 5
HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Nature communications. 2023 Academic Article GET IT
Times cited: 68
Identification of new hit to lead magmas inhibitors as potential therapeutics for glioblastoma. Bioorganic & medicinal chemistry letters. 2023 Academic Article GET IT
Times cited: 1
Effects of retinoic acid receptor α modulators on developmental ethanol-induced neurodegeneration and neuroinflammation. Frontiers in neuroscience. 2023 Academic Article GET IT
Times cited: 1
Anti-inflammatory Action of BT75, a Novel RARα Agonist, in Cultured Microglia and in an Experimental Mouse Model of Alzheimer's Disease. Neurochemical research. 2023 Academic Article GET IT
Times cited: 11
Stimuli-Responsive Boron-Based Materials in Drug Delivery. International journal of molecular sciences. 2023 Review GET IT
Times cited: 45
Development of a New Methodology for Dearomative Borylation of Coumarins and Chromenes and Its Applications to Synthesize Boron-Containing Retinoids. Molecules (Basel, Switzerland). 2023 Academic Article GET IT
Times cited: 2
TYRO3 agonist as therapy for glomerular disease. JCI insight. 2023 Academic Article GET IT
Times cited: 12
New Boron Delivery Agents. Cancer biotherapy & radiopharmaceuticals. 2022 Review GET IT
Times cited: 32
A novel procedure for the synthesis of borylated quinolines and its application in the development of potential boron-based homeodomain interacting protein kinase 2 (HIPK2) inhibitors. RSC advances. 2022 Academic Article GET IT
Times cited: 5
Tackling chronic kidney disease in diabetic patients with finerenone. Trends in pharmacological sciences. 2022 Academic Article GET IT
Magmas Inhibition in Prostate Cancer: A Novel Target for Treatment-Resistant Disease. Cancers. 2022 Academic Article GET IT
Times cited: 8
The Role of Microbiome in Brain Development and Neurodegenerative Diseases. Molecules (Basel, Switzerland). 2022 Review GET IT
Times cited: 87
Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective. Molecules (Basel, Switzerland). 2022 Review GET IT
Times cited: 107
Boron-Containing heterocycles as promising pharmacological agents. Bioorganic & medicinal chemistry. 2022 Review GET IT
Times cited: 64
Synthesis of a boron-containing amidoxime reagent and its application to synthesize functionalized oxadiazole and quinazolinone derivatives. Tetrahedron letters. 2022 Academic Article GET IT
Times cited: 6
Interactions of a boron-containing levodopa derivative on D₂ dopamine receptor and its effects in a Parkinson disease model. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2021 Academic Article GET IT
Times cited: 7
AMPK mediates regulation of glomerular volume and podocyte survival. JCI insight. 2021 Academic Article GET IT
Times cited: 16
Implications of an Improved Model of the TSH Receptor Transmembrane Domain (TSHR-TMD-TRIO). Endocrinology. 2021 Academic Article GET IT
Times cited: 9
BF175 inhibits endometrial carcinoma through SREBP-regulated metabolic pathways in vitro. Molecular and cellular endocrinology. 2020 Academic Article GET IT
Times cited: 5
Role of SIRT1 in HIV-associated kidney disease. American journal of physiology. Renal physiology. 2020 Academic Article GET IT
Times cited: 17
Microbial communities modulating brain functioning and behaviors in zebrafish: A mechanistic approach. Microbial pathogenesis. 2020 Review GET IT
Times cited: 25
A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells. Adipocyte. 2019 Academic Article GET IT
Times cited: 13
Potential therapeutic roles of retinoids for prevention of neuroinflammation and neurodegeneration in Alzheimer's disease. Neural regeneration research. 2019 Review GET IT
Times cited: 75
Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes. Nature communications. 2019 Academic Article GET IT
Times cited: 139
SMARC-B1 deficient sinonasal carcinoma metastasis to the brain with next generation sequencing data: a case report of perineural invasion progressing to leptomeningeal invasion. 2019 GET IT
Times cited: 11
Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell chemical biology. 2019 Academic Article GET IT
Times cited: 20
Targeting STAT3 signaling in kidney disease. American journal of physiology. Renal physiology. 2019 Review GET IT
Times cited: 87
Involvement of AMP-activated protein kinase in neuroinflammation and neurodegeneration in the adult and developing brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2019 Review GET IT
Times cited: 58
Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma. Apoptosis : an international journal on programmed cell death. 2018 Academic Article GET IT
Times cited: 122
Magmas inhibition as a potential treatment strategy in malignant glioma. Journal of neuro-oncology. 2018 Academic Article GET IT
Times cited: 13
SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts. Journal of the American Society of Nephrology : JASN. 2018 Academic Article GET IT
Times cited: 18
Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury. Kidney international. 2018 Academic Article GET IT
Times cited: 192
Small molecules targeting LapB protein prevent Listeria attachment to catfish muscle. PloS one. 2017 Academic Article GET IT
Times cited: 5
The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. eLife. 2017 Academic Article GET IT
Times cited: 22
Neuroprotective effects of estrogen in CNS injuries: insights from animal models. Neuroscience and neuroeconomics. 2017 Academic Article GET IT
Not all boronic acids with a five-membered cycle induce tremor, neuronal damage and decreased dopamine. Neurotoxicology. 2017 Academic Article GET IT
Times cited: 11
A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-β1/Smad3 Pathway. Journal of the American Society of Nephrology : JASN. 2017 Academic Article GET IT
Times cited: 60
Radiolabeling and initial biological evaluation of [¹⁸F]KBM-1 for imaging RAR-α receptors in neuroblastoma. Bioorganic & medicinal chemistry letters. 2017 Academic Article GET IT
Times cited: 13
An oxidative stress-based mechanism of doxorubicin cytotoxicity suggests new therapeutic strategies in ABC-DLBCL. Blood. 2016 Academic Article GET IT
Times cited: 52
Retinoic acid signaling pathways in development and diseases. Bioorganic & medicinal chemistry. 2013 Review GET IT
Times cited: 229
Use of zebrafish in chemical biology and drug discovery. Future medicinal chemistry. 2013 Review GET IT
Times cited: 15
Boron chemicals in diagnosis and therapeutics. Future medicinal chemistry. 2013 Review GET IT
Times cited: 235
Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs. Tetrahedron letters. 2012 Academic Article GET IT
Times cited: 21
Design and synthesis of boron containing potential pan-RAR inverse agonists. Tetrahedron letters. 2012 Academic Article GET IT
Times cited: 9
Novel retinoic acid receptor alpha agonists for treatment of kidney disease. PloS one. 2011 Academic Article GET IT
Times cited: 43
Design and Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist. Tetrahedron letters. 2011 Academic Article GET IT
Times cited: 7
Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts. Tetrahedron letters. 2010 Academic Article GET IT
Times cited: 50
A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity. PloS one. 2010 Academic Article GET IT
Times cited: 20
Design and Synthesis of Potential New Apoptosis Agents: Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids. Tetrahedron letters. 2010 Academic Article GET IT
Times cited: 17
Design and synthesis of novel pinacolylboronate containing combretastatin 'antimitotic agent' analogues. Tetrahedron letters. 2009 Academic Article GET IT
Times cited: 15
Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl)ethanol. Chemical communications (Cambridge, England). 2009 Academic Article GET IT
Times cited: 12
A forward chemical screen using zebrafish embryos with novel 2-substituted 2H-chromene derivatives. Chemical biology & drug design. 2009 Academic Article GET IT
Times cited: 39
Synthesis of 2-substituted 2H-chromenes using potassium vinyltrifluoroborates. Tetrahedron letters. 2008 Academic Article GET IT
Times cited: 50

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Background

education and training

M.S., Berhampur University (India) 91
Ph.D., Indian Institute of Technology (India) 1999
M.Phil., University of Delhi (India) 1993
B.S., Utkal University (India) 1987

Contact

full name

Bhaskar Chandra Das

primary email

bcd2004@med.cornell.edu

VIVO Weill Cornell Medical College

Bhaskar Chandra Das Adjunct Associate Professor of Molecular Biology in Surgery

Publications

selected publications

Background

education and training

Contact

full name

primary email