Carver, Brett

Publications

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selected publications

Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes. Molecular cancer therapeutics. 2019 Academic Article GET IT
Times cited: 11
Surgical Management of Patients with Advanced Germ Cell Tumors Following Salvage Chemotherapy: Memorial Sloan Kettering Cancer Center (MSKCC) Experience. Urology. 2018 Academic Article GET IT
Times cited: 8
Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death. eLife. 2018 Academic Article GET IT
Times cited: 196
Histologic and Oncologic Outcomes Following Liver Mass Resection With Retroperitoneal Lymph Node Dissection in Patients With Nonseminomatous Germ Cell Tumor. Urology. 2018 Academic Article GET IT
Times cited: 7
A phase II study of the dual mTOR inhibitor MLN0128 in patients with metastatic castration resistant prostate cancer. Investigational new drugs. 2018 Academic Article GET IT
Times cited: 61
Clinical Outcome of Retroperitoneal Lymph Node Dissection after Chemotherapy in Patients with Pure Embryonal Carcinoma in the Orchiectomy Specimen. Urology. 2018 Academic Article GET IT
Times cited: 13
Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors. The Journal of experimental medicine. 2017 Academic Article GET IT
Times cited: 127
Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis. Nature communications. 2017 Academic Article GET IT
Times cited: 19
Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017. European urology. 2017 Conference Paper GET IT
Times cited: 307
Malignant Mesothelioma of the Tunica Vaginalis Testis: Outcomes Following Surgical Management Beyond Radical Orchiectomy. Urology. 2017 Academic Article GET IT
Times cited: 18
Bilateral Testicular Germ Cell Tumors in the Era of Multimodal Therapy. Urology. 2016 Academic Article GET IT
Times cited: 12
Clinical Outcome of Patients with Fibrosis/Necrosis at Post-Chemotherapy Retroperitoneal Lymph Node Dissection for Advanced Germ Cell Tumors. The Journal of urology. 2016 Academic Article GET IT
Times cited: 10
Pelvic Lymph Node Dissection in Patients Treated for Testis Cancer: The Memorial Sloan Kettering Cancer Center Experience. Urology. 2016 Academic Article GET IT
Times cited: 3
The Molecular Taxonomy of Primary Prostate Cancer. Cell. 2015 Academic Article GET IT
Times cited: 2287
Everolimus combined with gefitinib in patients with metastatic castration-resistant prostate cancer: Phase 1/2 results and signaling pathway implications. Cancer. 2015 Academic Article GET IT
Times cited: 28
Late Relapse of Testicular Germ Cell Tumors. The Urologic clinics of North America. 2015 Review GET IT
Times cited: 24
Desperation Postchemotherapy Retroperitoneal Lymph Node Dissection for Metastatic Germ Cell Tumors. The Urologic clinics of North America. 2015 Review GET IT
Times cited: 2
An allelic series of miR-17 ∼ 92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron. Nature genetics. 2015 Academic Article GET IT
Times cited: 94
Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis. Cancer discovery. 2015 Academic Article GET IT
Times cited: 24
Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ. Cancer cell. 2014 Academic Article GET IT
Times cited: 203
Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling. Molecular cancer therapeutics. 2014 Academic Article GET IT
Times cited: 30
Organoid cultures derived from patients with advanced prostate cancer. Cell. 2014 Academic Article GET IT
Times cited: 1161
Rates of teratoma and viable cancer at post-chemotherapy retroperitoneal lymph node dissection after induction chemotherapy for good risk nonseminomatous germ cell tumors. The Journal of urology. 2014 Academic Article GET IT
Times cited: 19
Strategies for targeting the androgen receptor axis in prostate cancer. Drug discovery today. 2014 Review GET IT
Times cited: 9
Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer. Molecular endocrinology (Baltimore, Md.). 2014 Academic Article GET IT
Times cited: 37
Inhibition of circulating dipeptidyl peptidase 4 activity in patients with metastatic prostate cancer. Molecular & cellular proteomics : MCP. 2014 Academic Article GET IT
Times cited: 27
Copy number alteration burden predicts prostate cancer relapse. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 272
Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis. Molecular oncology. 2014 Academic Article GET IT
Times cited: 51
Clinical outcomes of local and metastatic testicular sex cord-stromal tumors. The Journal of urology. 2014 Academic Article GET IT
Times cited: 43
Cabozantinib resolves bone scans in tumor-naïve mice harboring skeletal injuries. Molecular imaging. 2014 Academic Article GET IT
Times cited: 8
Primary retroperitoneal lymph node dissection in low-stage testicular germ cell tumors: a detailed pathologic study with clinical outcome analysis with special emphasis on patients who did not receive adjuvant therapy. Urology. 2013 Academic Article GET IT
Times cited: 14
Prostate cancer progression correlates with increased humoral immune response to a human endogenous retrovirus GAG protein. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Academic Article GET IT
Times cited: 41
Androgen receptor signaling regulates DNA repair in prostate cancers. Cancer discovery. 2013 Academic Article GET IT
Times cited: 430
Translating insights of AR signaling from mouse models. Translational andrology and urology. 2013 Review GET IT
ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss. Nature medicine. 2013 Academic Article GET IT
Times cited: 237
Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion. Nature genetics. 2013 Academic Article GET IT
Times cited: 124
β4 Integrin signaling induces expansion of prostate tumor progenitors. The Journal of clinical investigation. 2013 Academic Article GET IT
Times cited: 80
Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening. PloS one. 2012 Academic Article GET IT
Times cited: 24
Outcomes in patients with clinical stage III NSGCT who achieve complete clinical response to chemotherapy at extraretroperitoneal disease site. Urology. 2012 Academic Article GET IT
Times cited: 6
Impact of age on clinicopathological outcomes and recurrence-free survival after the surgical management of nonseminomatous germ cell tumour. BJU international. 2012 Academic Article GET IT
Times cited: 6
Feasibility study of a clinically-integrated randomized trial of modifications to radical prostatectomy. Trials. 2012 Academic Article GET IT
Times cited: 6
Improved clinical outcomes with high-dose image guided radiotherapy compared with non-IGRT for the treatment of clinically localized prostate cancer. International journal of radiation oncology, biology, physics. 2012 Academic Article GET IT
Times cited: 355
Clinical impact of residual extraretroperitoneal masses in patients with advanced nonseminomatous germ cell testicular cancer. Urology. 2012 Academic Article GET IT
Times cited: 20
Body mass index is associated with higher lymph node counts during retroperitoneal lymph node dissection. Urology. 2011 Academic Article GET IT
Times cited: 17
The role of lymphadenectomy for testicular cancer: indications, controversies, and complications. The Urologic clinics of North America. 2011 Review GET IT
Times cited: 11
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer cell. 2011 Academic Article GET IT
Times cited: 139
Retroperitoneal histologic findings of patients with elevated serum alpha-fetoprotein and pure seminoma at orchiectomy. Urology. 2011 Academic Article GET IT
Times cited: 10
Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer cell. 2011 Academic Article GET IT
Times cited: 995
Postchemotherapy surgery for germ cell tumors of the testis. Current opinion in oncology. 2011 Review GET IT
Times cited: 3
MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors. PloS one. 2011 Academic Article GET IT
Times cited: 72
Outcomes after resection of postchemotherapy residual neck mass in patients with germ cell tumors--an update. Urology. 2011 Academic Article GET IT
Times cited: 11
Contemporary lymph node counts during primary retroperitoneal lymph node dissection. Urology. 2010 Academic Article GET IT
Times cited: 14
Evaluation of lymph node counts in primary retroperitoneal lymph node dissection. Cancer. 2010 Academic Article GET IT
Times cited: 27
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature. 2010 Academic Article GET IT
Times cited: 2026
Integrative genomic profiling of human prostate cancer. Cancer cell. 2010 Academic Article GET IT
Times cited: 3012
The total number of retroperitoneal lymph nodes resected impacts clinical outcome after chemotherapy for metastatic testicular cancer. Urology. 2010 Academic Article GET IT
Times cited: 44
Surgery for retroperitoneal relapse in the setting of a prior retroperitoneal lymph node dissection for germ cell tumor. Indian journal of urology : IJU : journal of the Urological Society of India. 2010 Academic Article GET IT
Times cited: 2
Differential p53-independent outcomes of p19(Arf) loss in oncogenesis. Science signaling. 2009 Academic Article GET IT
Times cited: 59
Location, extent and number of positive surgical margins do not improve accuracy of predicting prostate cancer recurrence after radical prostatectomy. The Journal of urology. 2009 Academic Article GET IT
Times cited: 144
Against: The case for cytoreductive nephrectomy for the management of metastatic renal cell carcinoma. The Journal of urology. 2009 Comment GET IT
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nature genetics. 2009 Academic Article GET IT
Times cited: 542
ETS rearrangements and prostate cancer initiation. Nature. 2009 Comment GET IT
Times cited: 95
Preservation of ejaculation in patients undergoing nerve-sparing postchemotherapy retroperitoneal lymph node dissection for metastatic testicular cancer. Urology. 2008 Academic Article GET IT
Times cited: 99
Clinical outcome and predictors of survival in late relapse of germ cell tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 85
Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events. Genes & development. 2008 Academic Article GET IT
Times cited: 104
The indication for postchemotherapy lymph node dissection in clinical stage IS nonseminomatous germ cell tumor. Cancer. 2008 Academic Article GET IT
Times cited: 17
Improved clinical outcome in recent years for men with metastatic nonseminomatous germ cell tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2007 Academic Article GET IT
Times cited: 58
Secondary therapy, metastatic progression, and cancer-specific mortality in men with clinically high-risk prostate cancer treated with radical prostatectomy. European urology. 2007 Academic Article GET IT
Times cited: 163
Incidence of metastatic nonseminomatous germ cell tumor outside the boundaries of a modified postchemotherapy retroperitoneal lymph node dissection. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2007 Academic Article GET IT
Times cited: 109
Radical prostatectomy for clinically localized, high risk prostate cancer: critical analysis of risk assessment methods. The Journal of urology. 2007 Academic Article GET IT
Times cited: 161
Adult and pediatric testicular teratoma. The Urologic clinics of North America. 2007 Review GET IT
Times cited: 25
Clinical outcome following post-chemotherapy retroperitoneal lymph node dissection in men with intermediate- and poor-risk nonseminomatous germ cell tumour. BJU international. 2007 Academic Article GET IT
Times cited: 21
Incidence of disease outside modified retroperitoneal lymph node dissection templates in clinical stage I or IIA nonseminomatous germ cell testicular cancer. The Journal of urology. 2007 Academic Article GET IT
Times cited: 74
Pathologic findings and clinical outcome of patients undergoing retroperitoneal lymph node dissection after multiple chemotherapy regimens for metastatic testicular germ cell tumors. Cancer. 2007 Academic Article GET IT
Times cited: 51
Long-term clinical outcome after postchemotherapy retroperitoneal lymph node dissection in men with residual teratoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2007 Academic Article GET IT
Times cited: 70
Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell. 2007 Academic Article GET IT
Times cited: 622
Impact of positive surgical margins in patients undergoing partial nephrectomy for renal cortical tumours. BJU international. 2006 Academic Article GET IT
Times cited: 108
African-American race is a predictor of prostate cancer detection: incorporation into a pre-biopsy nomogram. BJU international. 2006 Academic Article GET IT
Times cited: 40
Mouse modeling in oncologic preclinical and translational research. Clinical cancer research : an official journal of the American Association for Cancer Research. 2006 Review GET IT
Times cited: 49
Long-term outcome following radical prostatectomy in men with clinical stage T3 prostate cancer. The Journal of urology. 2006 Academic Article GET IT
Times cited: 187
Predicting teratoma in the retroperitoneum in men undergoing post-chemotherapy retroperitoneal lymph node dissection. The Journal of urology. 2006 Academic Article GET IT
Times cited: 56
Prostate cancer in patients with an abnormal digital rectal examination and serum prostate-specific antigen less than 4.0 ng/mL. Urology. 2005 Academic Article GET IT
Times cited: 38
Germ cell tumors of the testis. Annals of surgical oncology. 2005 Review GET IT
Times cited: 44
The current status of laparoscopic retroperitoneal lymph node dissection for non-seminomatous germ-cell tumors. Nature clinical practice. Urology. 2005 Review GET IT
Times cited: 13
Race is not a predictor of prostate cancer detection on repeat prostate biopsy. The Journal of urology. 2004 Academic Article GET IT
Times cited: 9
Do concerns about more advanced pathological features increase the likelihood of neurovascular bundle resection in black men undergoing radical prostatectomy?. The Journal of urology. 2004 Academic Article GET IT
The prevalence of men with National Institutes of Health category IV prostatitis and association with serum prostate specific antigen. The Journal of urology. 2003 Academic Article GET IT
Times cited: 78
Squamous cell carcinoma of the penis: a retrospective review of forty-five patients in northwest Louisiana. Southern medical journal. 2002 Academic Article GET IT
Times cited: 11
Treatment of chronic prostatitis lowers serum prostate specific antigen. The Journal of urology. 2002 Academic Article GET IT
Times cited: 110
Clinical stage T1c prostate cancer: pathologic outcomes following radical prostatectomy in black and white men. The Prostate. 2002 Academic Article GET IT
Times cited: 15
The incidence and implications of renal cell carcinoma in cadaveric renal transplants at the time of organ recovery. Transplantation. 1999 Academic Article GET IT
Times cited: 32

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Background

education and training

B.S., University of New Orleans 94
M.D., Louisiana State University School of Medicine 1998

Contact

full name

Brett Carver

VIVO Weill Cornell Medical College

Brett Carver Associate Professor of Urology

Publications

selected publications

Background

education and training

Contact

full name