selected publications
- Identifying transglutaminase substrate glutaminyls using dansylcadaverine. Analytical biochemistry. 2025 Academic Article GET IT
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Bacteria exploit viral dormancy to establish CRISPR-Cas immunity.
Cell host & microbe.
2025
Academic Article
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Times cited: 2 -
Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense.
Cell reports.
2024
Academic Article
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Times cited: 13 -
PlyKp104, a Novel Phage Lysin for the Treatment of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Other Gram-Negative ESKAPE Pathogens.
Antimicrobial agents and chemotherapy.
2023
Academic Article
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Times cited: 32 -
PaP1, a Broad-Spectrum Lysin-Derived Cationic Peptide to Treat Polymicrobial Skin Infections.
Frontiers in microbiology.
2022
Academic Article
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Times cited: 11 -
Watch your Strep: Streptococcus pyogenes is a preventable cause of maternal death.
Future microbiology.
2022
Academic Article
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Times cited: 1 -
Prophage integration into CRISPR loci enables evasion of antiviral immunity in Streptococcus pyogenes.
Nature microbiology.
2021
Academic Article
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Times cited: 29 -
A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression.
Cell.
2021
Academic Article
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Times cited: 57 -
Evaluation of Topical Lysostaphin as a Novel Treatment for Instrumented Rhesus Macaques (Macaca mulatta) Infected with Methicillin-Resistant Staphylococcus aureus.
Comparative medicine.
2020
Academic Article
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Times cited: 8 -
Gram-Negative Bacterial Lysins.
Antibiotics (Basel, Switzerland).
2020
Review
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Times cited: 99 -
Isolation of Phage Lysins That Effectively Kill Pseudomonas aeruginosa in Mouse Models of Lung and Skin Infection.
Antimicrobial agents and chemotherapy.
2019
Academic Article
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Times cited: 91 -
Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria.
Antimicrobial agents and chemotherapy.
2019
Academic Article
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Times cited: 86 -
Staphylococcus aureus Infecting and Colonizing Experimental Animals, Macaques, in a Research Animal Facility.
Microbial drug resistance (Larchmont, N.Y.).
2018
Academic Article
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Times cited: 4 -
Strains of bacterial species induce a greatly varied acute adaptive immune response: The contribution of the accessory genome.
PLoS pathogens.
2018
Academic Article
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Times cited: 60 -
The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa.
PloS one.
2017
Academic Article
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Times cited: 35 -
Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii.
Antimicrobial agents and chemotherapy.
2016
Academic Article
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Times cited: 117 -
Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique.
PloS one.
2016
Academic Article
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Times cited: 25 -
Elimination of Chromosomal Island SpyCIM1 from Streptococcus pyogenes Strain SF370 Reverses the Mutator Phenotype and Alters Global Transcription.
PloS one.
2015
Academic Article
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Times cited: 15 -
Using a Novel Lysin To Help Control Clostridium difficile Infections.
Antimicrobial agents and chemotherapy.
2015
Academic Article
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Times cited: 53 -
A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy.
2015
Academic Article
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Times cited: 107 -
Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model.
Antimicrobial agents and chemotherapy.
2015
Academic Article
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Times cited: 224 -
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.
Nature biotechnology.
2014
Academic Article
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Times cited: 763 -
A highly active and negatively charged Streptococcus pyogenes lysin with a rare D-alanyl-L-alanine endopeptidase activity protects mice against streptococcal bacteremia.
Antimicrobial agents and chemotherapy.
2014
Academic Article
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Times cited: 49 -
Use of a bacteriophage lysin to identify a novel target for antimicrobial development.
PloS one.
2013
Academic Article
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Times cited: 45 -
Novel bacteriophage lysin with broad lytic activity protects against mixed infection by Streptococcus pyogenes and methicillin-resistant Staphylococcus aureus.
Antimicrobial agents and chemotherapy.
2013
Academic Article
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Times cited: 183 -
Novel algorithms reveal streptococcal transcriptomes and clues about undefined genes.
PLoS computational biology.
2007
Academic Article
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Times cited: 14 -
M.SpyI, a DNA methyltransferase encoded on a mefA chimeric element, modifies the genome of Streptococcus pyogenes.
Journal of bacteriology.
2006
Academic Article
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Times cited: 22