Zhu, Chenxu

Publications

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selected publications

Single-cell 5-hydroxymethylcytosine landscapes of mouse early embryos at single-base resolution. Cell reports. 2025 Academic Article GET IT
Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability. Nature methods. 2025 Academic Article GET IT
SIMPLE-seq to decode DNA methylation dynamics in single cells. Nature reviews. Genetics. 2024 Academic Article GET IT
Omics Approaches to Investigate the Pathogenesis of Suicide. Biological psychiatry. 2024 Review GET IT
Times cited: 4
Simultaneous single-cell analysis of 5mC and 5hmC with SIMPLE-seq. Nature biotechnology. 2024 Academic Article GET IT
Times cited: 15
SnapHiC-D: a computational pipeline to identify differential chromatin contacts from single-cell Hi-C data. Briefings in bioinformatics. 2023 Academic Article GET IT
Times cited: 4
SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data. Nature communications. 2023 Academic Article GET IT
Times cited: 4
Droplet-based single-cell joint profiling of histone modifications and transcriptomes. Nature structural & molecular biology. 2023 Academic Article GET IT
Times cited: 26
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proceedings of the National Academy of Sciences of the United States of America. 2023 Academic Article GET IT
Times cited: 11
Single-Cell Joint Profiling of Open Chromatin and Transcriptome by Paired-Seq. Methods in molecular biology (Clifton, N.J.). 2023 Academic Article GET IT
Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain. Cell research. 2022 Academic Article GET IT
Times cited: 39
DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nature communications. 2021 Academic Article GET IT
Times cited: 14
Joint profiling of histone modifications and transcriptome in single cells from mouse brain. Nature methods. 2021 Academic Article GET IT
Times cited: 189
Transposase-assisted tagmentation of RNA/DNA hybrid duplexes. eLife. 2020 Academic Article GET IT
Times cited: 40
Single-cell multimodal omics: the power of many. Nature methods. 2020 Academic Article GET IT
Times cited: 267
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation. Nature chemical biology. 2019 Academic Article GET IT
Times cited: 87
An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome. Nature structural & molecular biology. 2019 Academic Article GET IT
Times cited: 228
Single-Cell 5fC Sequencing. Methods in molecular biology (Clifton, N.J.). 2019 Academic Article GET IT
Times cited: 2
Bisulfite-Free, Nanoscale Analysis of 5-Hydroxymethylcytosine at Single Base Resolution. Journal of the American Chemical Society. 2018 Academic Article GET IT
Times cited: 79
Genome-wide mapping reveals that deoxyuridine is enriched in the human centromeric DNA. Nature chemical biology. 2018 Academic Article GET IT
Times cited: 49
Deciphering TAL effectors for 5-methylcytosine and 5-hydroxymethylcytosine recognition. Nature communications. 2017 Academic Article GET IT
Times cited: 31
Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution. Cell stem cell. 2017 Academic Article GET IT
Times cited: 135
Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair. Proceedings of the National Academy of Sciences of the United States of America. 2016 Academic Article GET IT
Times cited: 51
Biochemical and Structural Insights into the Mechanism of DNA Recognition by Arabidopsis ETHYLENE INSENSITIVE3. PloS one. 2015 Academic Article GET IT
Times cited: 30
Oxidative demethylation of DNA and RNA mediated by non-heme iron-dependent dioxygenases. Chemistry, an Asian journal. 2014 Review GET IT
Times cited: 11
Switching demethylation activities between AlkB family RNA/DNA demethylases through exchange of active-site residues. Angewandte Chemie (International ed. in English). 2014 Academic Article GET IT
Times cited: 54

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Research

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Funding awarded

Studying the Regulatory Dynamics with Single-cell Multiomics awarded by National Institute of General Medical Sciences Principal Investigator Subaward 2023 - 2026

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Background

education and training

Ph.D., Peking University (China) 2017
M.S., Wuhan University (China) 2011

Contact

full name

Chenxu Zhu

primary email

chz4007@med.cornell.edu

VIVO Weill Cornell Medical College

Chenxu Zhu Assistant Professor of Physiology and Biophysics

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email