Henchcliffe, Claire

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Investigational Gene Therapies for Parkinson's Disease. CNS drugs. 2025 Review GET IT
Recent advances in fluid and tissue-based biomarkers for use in Parkinson's disease. Expert review of neurotherapeutics. 2025 Review GET IT
Convention vs. innovation III: The promise of stem cell therapy in Parkinson's disease remains bright. Parkinsonism & related disorders. 2025 Academic Article GET IT
Phase I trial of hES cell-derived dopaminergic neurons for Parkinson's disease. Nature. 2025 Academic Article GET IT
Identification of Parkinson's disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data. NPJ digital medicine. 2024 Academic Article GET IT
Learning Phenotypic Associations for Parkinson's Disease with Longitudinal Clinical Records. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. 2024 Academic Article GET IT
Neurologic and psychiatric features of impending neurodegeneration in iRBD. Clinical parkinsonism & related disorders. 2023 Academic Article GET IT
Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy. Orphanet journal of rare diseases. 2022 Review GET IT
Times cited: 26
Comprehensive subtyping of Parkinson's disease patients with similarity fusion: a case study with BioFIND data. NPJ Parkinson's disease. 2021 Academic Article GET IT
Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA. 2021 Academic Article GET IT
Times cited: 120
Contemporary Neuroscience Core Curriculum for Medical Schools. Neurology. 2021 Academic Article GET IT
Comparison of the Parkinson's KinetiGraph to off/on levodopa response testing: Single center experience. Clinical neurology and neurosurgery. 2021 Academic Article GET IT
Characteristics and Outcomes of Parkinson's Disease Individuals Hospitalized with COVID-19 in a New York City Hospital System. Movement disorders clinical practice. 2021 Academic Article GET IT
Baseline Differences in Long-term Survivors and Nonsurvivors of the Colorado/Columbia Fetal Implant Trial. Journal of the International Neuropsychological Society : JINS. 2021 Academic Article GET IT
Population-based input function for TSPO quantification and kinetic modeling with [¹¹C]-DPA-713. EJNMMI physics. 2021 Academic Article GET IT
Tablet-based patient educational interventions in care and management of complex movement disorders. Disability and rehabilitation. Assistive technology. 2021 Academic Article GET IT
Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Cell stem cell. 2021 Academic Article GET IT
Times cited: 180
Can google glass™ technology improve freezing of gait in parkinsonism? A pilot study. Disability and rehabilitation. Assistive technology. 2020 Academic Article GET IT
Times cited: 2
Toward a Personalized Approach to Parkinson's Cell Therapy. Movement disorders : official journal of the Movement Disorder Society. 2020 Letter GET IT
Times cited: 3
Molecular Imaging of Striatal Dopaminergic Neuronal Loss and the Neurovascular Unit in Parkinson Disease. Frontiers in neuroscience. 2020 Academic Article GET IT
Times cited: 11
A machine learning and network framework to discover new indications for small molecules. PLoS computational biology. 2020 Academic Article GET IT
Times cited: 17
Comorbid neuropsychiatric and autonomic features in REM sleep behavior disorder. Clinical parkinsonism & related disorders. 2020 Academic Article GET IT
The future of stem cell therapies for Parkinson disease. Nature reviews. Neuroscience. 2020 Information Resource GET IT
Times cited: 51
Neurophysiological Biomarkers of Parkinson's Disease. Journal of Parkinson's disease. 2020 Academic Article GET IT
Times cited: 58
Sex and Gender Driven Modifiers of Alzheimer's: The Role for Estrogenic Control Across Age, Race, Medical, and Lifestyle Risks. Frontiers in aging neuroscience. 2019 Information Resource GET IT
Times cited: 131
Motor phenotype classification in moderate to advanced PD in BioFIND study. Parkinsonism & related disorders. 2019 Academic Article GET IT
Times cited: 25
Data-Driven Subtyping of Parkinson's Disease Using Longitudinal Clinical Records: A Cohort Study. Scientific reports. 2019 Academic Article GET IT
Times cited: 105
18F-FPEB PET/CT Shows mGluR5 Upregulation in Parkinson's Disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2018 Academic Article GET IT
Times cited: 12
Rapid eye movement sleep behavior disorder and the link to alpha-synucleinopathies. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2018 Information Resource GET IT
Times cited: 72
Noninvasive PK11195-PET Image Analysis Techniques Can Detect Abnormal Cerebral Microglial Activation in Parkinson's Disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2018 Academic Article GET IT
Times cited: 27
Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies. Journal of Parkinson's disease. 2018 Information Resource GET IT
Times cited: 20
Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features. Movement disorders : official journal of the Movement Disorder Society. 2017 Academic Article GET IT
Times cited: 128
Evidence for the use of pimavanserin in the treatment of Parkinson's disease psychosis. Therapeutic advances in neurological disorders. 2016 Information Resource GET IT
The BioFIND study: Characteristics of a clinically typical Parkinson's disease biomarker cohort. Movement disorders : official journal of the Movement Disorder Society. 2016 Academic Article GET IT
Times cited: 49
Future needs for informed consent in stem cell clinical trials in neurodegenerative diseases. Neural regeneration research. 2016 Academic Article GET IT
Times cited: 7
First-in-human cell transplant trials in Parkinson's disease: The need for an improved informed consent process. Parkinsonism & related disorders. 2015 Article GET IT
Times cited: 12
Dance for PD: a preliminary investigation of effects on motor function and quality of life among persons with Parkinson's disease (PD). Journal of neural transmission (Vienna, Austria : 1996). 2015 Academic Article GET IT
Times cited: 42
A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA neurology. 2014 Academic Article GET IT
Times cited: 206
Sex differences in cerebral energy metabolism in Parkinson's disease: a phosphorus magnetic resonance spectroscopic imaging study. Parkinsonism & related disorders. 2014 Academic Article GET IT
Times cited: 14
Usefulness of proton and phosphorus MR spectroscopic imaging for early diagnosis of Parkinson's disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2013 Academic Article GET IT
Times cited: 26
Neuroimaging markers of motor and nonmotor features of Parkinson's disease: an 18f fluorodeoxyglucose positron emission computed tomography study. Dementia and geriatric cognitive disorders. 2013 Academic Article GET IT
Times cited: 69
Biomarkers in Parkinson's disease: an update. Current opinion in neurology. 2012 Information Resource GET IT
Times cited: 52
Clinical characteristics of exacerbations in Parkinson disease. The neurologist. 2012 Academic Article GET IT
Times cited: 52
Biomarkers of Parkinson's disease and Dementia with Lewy bodies. Progress in neurobiology. 2011 Information Resource GET IT
Times cited: 24
The role of dopaminergic imaging in patients with symptoms of dopaminergic system neurodegeneration. Brain : a journal of neurology. 2011 Information Resource GET IT
Times cited: 135
Detection of retinal changes in Parkinson's disease with spectral-domain optical coherence tomography. Clinical ophthalmology (Auckland, N.Z.). 2010 Academic Article GET IT
Times cited: 119
Clinical predictors of frequent patient telephone calls in Parkinson's disease. Parkinsonism & related disorders. 2010 Academic Article GET IT
Times cited: 18
How are we doing with the treatment of essential tremor (ET)?: Persistence of patients with ET on medication: data from 528 patients in three settings. European journal of neurology. 2010 Academic Article GET IT
Times cited: 98
Coenzyme Q10 effects in neurodegenerative disease. Neuropsychiatric disease and treatment. 2009 Academic Article GET IT
Mirror movements in patients with essential tremor. Movement disorders : official journal of the Movement Disorder Society. 2009 Academic Article GET IT
Times cited: 22
Metabolomic profiling in LRRK2-related Parkinson's disease. PloS one. 2009 Academic Article GET IT
Times cited: 144
Older onset essential tremor: More rapid progression and more degenerative pathology. Movement disorders : official journal of the Movement Disorder Society. 2009 Academic Article GET IT
Times cited: 71
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nature clinical practice. Neurology. 2008 Information Resource GET IT
Times cited: 524
Cancer and blood concentrations of the comutagen harmane in essential tremor. Movement disorders : official journal of the Movement Disorder Society. 2008 Academic Article GET IT
Times cited: 9
Rasagiline in treatment of Parkinson's disease. Neuropsychiatric disease and treatment. 2008 Academic Article GET IT
Case study of an unusual variant of restless leg syndrome. Movement disorders : official journal of the Movement Disorder Society. 2008 Article GET IT
Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor. Neurotoxicology. 2007 Academic Article GET IT
Times cited: 81
Young-onset Parkinson's disease: hospital utilization and medical comorbidity in a nationwide survey. Neuroepidemiology. 2007 Academic Article GET IT
Times cited: 10
Retraction. Young-onset Parkinson's disease: hospital utilization and medical comorbidity in a nationwide survey. Movement disorders : official journal of the Movement Disorder Society. 2007 Academic Article GET IT
Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 2006 Academic Article GET IT
Times cited: 142
Late-life depression: a neuropsychiatric approach. Expert review of neurotherapeutics. 2006 Review GET IT
Times cited: 17
Recent advances in Parkinson's disease therapy: use of monoamine oxidase inhibitors. Expert review of neurotherapeutics. 2005 Information Resource GET IT
Times cited: 27
Intravascular lymphoma: magnetic resonance imaging correlates of disease dynamics within the central nervous system. Journal of neurology, neurosurgery, and psychiatry. 2005 Academic Article GET IT
Times cited: 81
Expression of c-fos, c-jun, and c-jun N-terminal kinase (JNK) in a developmental model of induced apoptotic death in neurons of the substantia nigra. Journal of neurochemistry. 1999 Academic Article GET IT
Times cited: 77
Increased expression of cyclin-dependent kinase 5 in induced apoptotic neuron death in rat substantia nigra. Neuroscience letters. 1997 Academic Article GET IT
Times cited: 46
Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1996 Academic Article GET IT
Times cited: 52
Apoptosis in substantia nigra following developmental hypoxic-ischemic injury. Neuroscience. 1995 Academic Article GET IT
Times cited: 65
Genetic analysis of laminin A reveals diverse functions during morphogenesis in Drosophila. Development (Cambridge, England). 1993 Academic Article GET IT
Times cited: 82
Cell type specific trans-acting factors are involved in alternative splicing of human fibronectin pre-mRNA. The EMBO journal. 1989 Academic Article GET IT
Times cited: 44
Sequence analysis and in vivo expression show that alternative splicing of ED-B and ED-A regions of the human fibronectin gene are independent events. Nucleic acids research. 1988 Academic Article GET IT
Times cited: 25

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Research

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Funding awarded

Quantitative Mapping of Substantia Nigra Iron in Parkinson''s Disease awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2016 - 2023
missing activity Co-Investigator 2016 - 2023

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Background

education and training

M.D., Columbia University College of Physicians and Surgeons 1997
D.Phil., Oxford University (United Kingdom) 1992
M.A., Oxford University (United Kingdom) 1988
B.A., Oxford University (United Kingdom) 1985

Contact

full name

Claire Henchcliffe

primary email

clh2007@med.cornell.edu

VIVO Weill Cornell Medical College

Claire Henchcliffe Adjunct Professor of Neurology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email