selected publications
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An exosome pathway without an ESCRT.
Cell research.
2021
Comment
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Times cited: 67 -
Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids.
STAR protocols.
2020
Academic Article
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Times cited: 27 -
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell.
2020
Academic Article
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Times cited: 934 -
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.
Developmental cell.
2020
Academic Article
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Times cited: 98 -
Non-reversible tissue fixation retains extracellular vesicles for in situ imaging.
Nature methods.
2019
Academic Article
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Times cited: 18 -
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis.
Nature cell biology.
2019
Academic Article
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Times cited: 341 -
Exosome-Mediated Metastasis: Communication from a Distance.
Developmental cell.
2019
Information Resource
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Times cited: 239 -
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Nature cell biology.
2018
Academic Article
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Times cited: 1348 -
NBR1 enables autophagy-dependent focal adhesion turnover.
The Journal of cell biology.
2016
Academic Article
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Times cited: 136 -
Potent benzoazepinone γ-secretase modulators with improved bioavailability.
Bioorganic & medicinal chemistry letters.
2015
Academic Article
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Times cited: 8 -
Cellular and metabolic functions for autophagy in cancer cells.
Trends in cell biology.
2014
Information Resource
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Times cited: 235 -
Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion.
Cancer discovery.
2014
Academic Article
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Times cited: 243 -
Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor.
ACS medicinal chemistry letters.
2014
Academic Article
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Times cited: 27 -
Triazoles as γ-secretase modulators.
Bioorganic & medicinal chemistry letters.
2011
Academic Article
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Times cited: 18 -
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation.
Molecular biology of the cell.
2010
Academic Article
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Times cited: 416 -
Purine derivatives as potent gamma-secretase modulators.
Bioorganic & medicinal chemistry letters.
2010
Academic Article
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Times cited: 33 -
Autophagy and metastasis: another double-edged sword.
Current opinion in cell biology.
2009
Information Resource
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Times cited: 291 -
Fluorinated piperidine acetic acids as gamma-secretase modulators.
Bioorganic & medicinal chemistry letters.
2009
Academic Article
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Times cited: 31 -
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.
Gastroenterology.
2009
Academic Article
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Times cited: 150 -
Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization.
Bioorganic & medicinal chemistry letters.
2008
Academic Article
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Times cited: 20 -
SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2).
Bioorganic & medicinal chemistry letters.
2008
Academic Article
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Times cited: 39 -
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2).
Bioorganic & medicinal chemistry letters.
2008
Academic Article
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Times cited: 137 -
Targeted degradation of the AML1/MDS1/EVI1 oncoprotein by arsenic trioxide.
Cancer research.
2006
Academic Article
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Times cited: 39