selected publications
- CD19 CAR antigen engagement mechanisms and affinity tuning. Science immunology. 2023 Academic Article GET IT
- Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path. ACS bio & med chem Au. 2022 Academic Article GET IT
- Simulation of pH-Dependent Conformational Transitions in Membrane Proteins: The CLC-ec1 Cl-/H+ Antiporter. Molecules (Basel, Switzerland). 2021 Academic Article GET IT
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A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs.
Molecules (Basel, Switzerland).
2019
Academic Article
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Times cited: 35 -
Molecular Dynamics Methodologies for Probing Cannabinoid Ligand/Receptor Interaction.
2017
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Times cited: 5 -
Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones.
Bioorganic & medicinal chemistry letters.
2016
Academic Article
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Times cited: 6 -
(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.
Molecular pharmacology.
2014
Academic Article
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Times cited: 3 -
CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides.
Journal of medicinal chemistry.
2014
Academic Article
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Times cited: 47 -
Pregnenolone can protect the brain from cannabis intoxication.
Science (New York, N.Y.).
2014
Academic Article
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Times cited: 233 -
Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling.
The Journal of biological chemistry.
2013
Academic Article
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Times cited: 64 -
Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.
Biochemistry.
2013
Academic Article
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Times cited: 40 -
Novel insights into CB1 cannabinoid receptor signaling: a key interaction identified between the extracellular-3 loop and transmembrane helix 2.
The Journal of pharmacology and experimental therapeutics.
2013
Academic Article
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Times cited: 17