Colak, Dilek

Publications

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selected publications

Extracellular vesicle profiling reveals novel autism signatures in patient-derived forebrain organoids. Translational psychiatry. 2025 Academic Article GET IT
Extracellular Vesicle Profiling Reveals Novel Autism Signatures in Patient-Derived Forebrain Organoids. 2025 GET IT
[Comparison of Cytomegalovirus Polymerase Chain Reaction Test Results Obtained with Fully Automated Systems: Roche Cobas 6800 and Qiagen NeuMoDx Experience]. Mikrobiyoloji bulteni. 2024 Academic Article GET IT
Schizophrenia endothelial cells exhibit higher permeability and altered angiogenesis patterns in patient-derived organoids. Translational psychiatry. 2024 Academic Article GET IT
Times cited: 14
Circadian protein TIMELESS regulates synaptic function and memory by modulating cAMP signaling. Cell reports. 2023 Academic Article GET IT
Times cited: 9
The evolution of BDNF is defined by strict purifying selection and prodomain spatial coevolution, but what does it mean for human brain disease?. Translational psychiatry. 2022 Academic Article GET IT
Times cited: 9
Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca²⁺ signaling. Molecular psychiatry. 2022 Academic Article GET IT
Times cited: 49
Prenatal Drugs and Their Effects on the Developing Brain: Insights From Three-Dimensional Human Organoids. Frontiers in neuroscience. 2022 Review GET IT
Times cited: 6
Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity. Cell. 2022 Academic Article GET IT
Times cited: 225
Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids. Molecular psychiatry. 2021 Academic Article GET IT
Times cited: 87
The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors. Translational psychiatry. 2021 Academic Article GET IT
Times cited: 37
Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids. Molecular psychiatry. 2021 Academic Article GET IT
Times cited: 29
UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function. Molecular psychiatry. 2019 Academic Article GET IT
Times cited: 27
Coupled local translation and degradation regulate growth cone collapse. Nature communications. 2015 Academic Article GET IT
Times cited: 47
Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome. Science (New York, N.Y.). 2014 Academic Article GET IT
Times cited: 251
The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells. Molecular cell. 2013 Academic Article GET IT
Times cited: 87
Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay. Cell. 2013 Academic Article GET IT
Times cited: 157
Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected]. Cell stem cell. 2013 Academic Article GET IT
Times cited: 227
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell stem cell. 2010 Academic Article GET IT
Times cited: 311
The specific role of histone deacetylase 2 in adult neurogenesis. Neuron glia biology. 2010 Academic Article GET IT
Times cited: 82
Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain. Proceedings of the National Academy of Sciences of the United States of America. 2008 Academic Article GET IT
Times cited: 649
Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Academic Article GET IT
Times cited: 228
Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina. Neural development. 2007 Academic Article GET IT
Times cited: 37
Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 328

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Research

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Funding awarded

Astrocyte RNA degradation and cognitive function awarded by National Institute of Mental Health Principal Investigator 2022 - 2027
Astrocytic function of the novel ASD-risk gene GIGYF1 in brain development awarded by Simons Foundation Autism Research Initiative Principal Investigator 2024 - 2026
Exploring exosomes in neurodevelopmental and neuropsychiatric diseases using brain organoids awarded by National Institute of Mental Health Principal Investigator 2023 - 2026
missing activity Principal Investigator 2019 - 2025

Uncovering the role of astrocyte RNA regulation in the central nervous system awarded by Leon Levy Foundation Co-Principal Investigator 2023 - 2026

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Background

education and training

Ph.D., Ludwig Maximilian University of Munich (Germany) 2008
B.S., Hacettepe University (Turkey) 2003

Contact

full name

Dilek Colak

primary email

dic2009@med.cornell.edu

VIVO Weill Cornell Medical College

Dilek Colak Associate Professor of Neuroscience

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email