James, Daylon J

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selected publications

Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells. APL bioengineering. 2023 Academic Article GET IT
Dual role of lipids for genome stability and pluripotency facilitates full potency of mouse embryonic stem cells. Protein & cell. 2023 Academic Article GET IT
Human theca arises from ovarian stroma and is comprised of three discrete subtypes. Communications biology. 2023 Academic Article GET IT
Ovarian Reserve Disorders, Can We Prevent Them? A Review. International journal of molecular sciences. 2022 Review GET IT
Extraction, Labeling, and Purification of Lineage-Specific Cells from Human Antral Follicles. Journal of visualized experiments : JoVE. 2022 Academic Article GET IT
Xenograft Model of Heterotopic Transplantation of Human Ovarian Cortical Tissue and Its Clinical Relevance. Reproduction (Cambridge, England). 2022 Academic Article GET IT
Chronic superphysiologic AMH promotes premature luteinization of antral follicles in human ovarian xenografts. Science advances. 2022 Academic Article GET IT
A message From the Media Editors of the Fertility and Sterility family of journals. Fertility and sterility. 2021 Editorial Article GET IT
Exogenous insulin-like growth factor 1 accelerates growth and maturation of follicles in human cortical xenografts and increases ovarian output in mice. F&S science. 2021 Academic Article GET IT
Times cited: 5
Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication. The Journal of cell biology. 2020 Academic Article GET IT
Times cited: 13
Comparison of Human Antral Follicles of Xenograft versus Ovarian Origin Reveals Disparate Molecular Signatures. Cell reports. 2020 Academic Article GET IT
Times cited: 10
Cycle day 2 insulin-like growth factor-1 serum levels as a prognostic tool to predict controlled ovarian hyperstimulation outcomes in poor responders. Fertility and sterility. 2020 Academic Article GET IT
Times cited: 2
Endothelial deletion of ADAM10, a key regulator of Notch signaling, causes impaired decidualization and reduced fertility in female mice. Angiogenesis. 2020 Academic Article GET IT
Times cited: 4
Multivalent biomaterial platform to control the distinct arterial venous differentiation of pluripotent stem cells. Biomaterials. 2018 Academic Article GET IT
Times cited: 8
Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery. Journal of visualized experiments : JoVE. 2018 Academic Article GET IT
Times cited: 17
Wnt inhibition promotes vascular specification of embryonic cardiac progenitors. Development (Cambridge, England). 2018 Academic Article GET IT
Times cited: 8
Engineered endothelium provides angiogenic and paracrine stimulus to grafted human ovarian tissue. Scientific reports. 2017 Academic Article GET IT
Times cited: 34
Notch hyper-activation drives trans-differentiation of hESC-derived endothelium. Stem cell research. 2016 Academic Article GET IT
Times cited: 8
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction. Nature. 2014 Academic Article GET IT
Times cited: 185
Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells. Stem cells (Dayton, Ohio). 2014 Academic Article GET IT
Times cited: 21
Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration. Developmental cell. 2013 Academic Article GET IT
Times cited: 488
Prominin 1/CD133 endothelium sustains growth of proneural glioma. PloS one. 2013 Academic Article GET IT
Times cited: 19
Wading through the waves of human embryonic hemogenesis. Cell cycle (Georgetown, Tex.). 2013 Editorial Article GET IT
Times cited: 2
Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition. Blood. 2012 Academic Article GET IT
Times cited: 65
Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell. 2012 Academic Article GET IT
Times cited: 195
Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells. Blood. 2012 Academic Article GET IT
Times cited: 83
Lentiviral transduction and clonal selection of hESCs with endothelial-specific transgenic reporters. Current protocols in stem cell biology. 2011 Academic Article GET IT
Times cited: 7
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature. 2010 Academic Article GET IT
Times cited: 663
New dimensions in vascular engineering: opportunities for cancer biology. Tissue engineering. Part A. 2010 Academic Article GET IT
Times cited: 2
Breaking ground on translational stem cell research. Annals of the New York Academy of Sciences. 2010 Conference Paper GET IT
Times cited: 5
Introduction to high-pressure bioscience and biotechnology. Annals of the New York Academy of Sciences. 2010 Article GET IT
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nature biotechnology. 2010 Academic Article GET IT
Times cited: 267
Generation of stable co-cultures of vascular cells in a honeycomb alginate scaffold. Tissue engineering. Part A. 2010 Academic Article GET IT
Times cited: 34
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell stem cell. 2009 Academic Article GET IT
Times cited: 519
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature. 2007 Academic Article GET IT
Times cited: 367
Contribution of human embryonic stem cells to mouse blastocysts. Developmental biology. 2006 Academic Article GET IT
Times cited: 119
TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development (Cambridge, England). 2005 Academic Article GET IT
Times cited: 700
In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice. Arteriosclerosis, thrombosis, and vascular biology. 2003 Academic Article GET IT
Times cited: 67
Expression of c-fos, c-jun, and c-jun N-terminal kinase (JNK) in a developmental model of induced apoptotic death in neurons of the substantia nigra. Journal of neurochemistry. 1999 Academic Article GET IT
Times cited: 77

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Research

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Funding awarded

Anti-Mullerian hormone for preserving ovarian function before administration of gonadotoxic therapies or after transplantation of cryopreserved tissue. awarded by National Institute of Child Health & Human Development Principal Investigator 2023 - 2028
Optimized protocols for ovarian tissue cryopreservation and novel modRNA-based approaches to improve transplantation outcomes for fertility preservation in chronically diseased girls awarded by National Institute of Child Health & Human Development Principal Investigator 2021 - 2024

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Background

education and training

Ph.D., The Rockefeller University 2006
B.S., Duke University 1999

Contact

full name

Daylon J James

primary email

djj2001@med.cornell.edu

VIVO Weill Cornell Medical College

Daylon J James Associate Professor of Stem Cell Biology in Obstetrics and Gynecology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email