selected publications
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A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis.
Neurology.
2016
Academic Article
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Times cited: 106 -
A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement.
Amyotrophic lateral sclerosis & frontotemporal degeneration.
2015
Academic Article
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Times cited: 26 -
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
Science (New York, N.Y.).
2015
Academic Article
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Times cited: 767 -
Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial.
The Lancet. Neurology.
2014
Academic Article
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Times cited: 189 -
Seeking a measure of clinically meaningful change in ALS.
Amyotrophic lateral sclerosis & frontotemporal degeneration.
2014
Academic Article
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Times cited: 8 -
Systemic pharmacokinetics and cerebrospinal fluid uptake of intravenous ceftriaxone in patients with amyotrophic lateral sclerosis.
Journal of clinical pharmacology.
2014
Academic Article
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Times cited: 19 -
TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis.
JAMA neurology.
2014
Academic Article
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Times cited: 217 -
Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet (London, England).
2014
Academic Article
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Times cited: 221 -
Design and initial results of a multi-phase randomized trial of ceftriaxone in amyotrophic lateral sclerosis.
PloS one.
2013
Academic Article
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Times cited: 95 -
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study.
The Lancet. Neurology.
2013
Academic Article
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Times cited: 534 -
Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis: examining a more efficient trial design.
Neurology.
2011
Academic Article
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Times cited: 66 -
Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P₂ phosphatase FIG4.
Brain : a journal of neurology.
2011
Academic Article
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Times cited: 112 -
Does apolipoprotein E genotype modify the clinical expression of ALS?.
European journal of neurology.
2010
Academic Article
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Times cited: 13 -
A decrease in body mass index is associated with faster progression of motor symptoms and shorter survival in ALS.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.
2010
Academic Article
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Times cited: 89 -
Toward more efficient clinical trials for amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.
2010
Information Resource
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Times cited: 59 -
ALS disease onset may occur later in patients with pre-morbid diabetes mellitus.
European journal of neurology.
2010
Academic Article
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Times cited: 68 -
Association between dysarthria and cognitive impairment in ALS: A prospective study.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.
2010
Academic Article
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Times cited: 18 -
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial.
Neurology.
2008
Academic Article
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Times cited: 222 -
Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis.
Neurology.
2008
Academic Article
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Times cited: 108 -
Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery.
PloS one.
2007
Academic Article
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Times cited: 16 -
Whole-genome analysis of sporadic amyotrophic lateral sclerosis.
The New England journal of medicine.
2007
Academic Article
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Times cited: 197 -
Predictability of disease progression in amyotrophic lateral sclerosis.
Muscle & nerve.
2006
Academic Article
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Times cited: 42 -
The value of database controls in pilot or futility studies in ALS.
Neurology.
2006
Academic Article
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Times cited: 16 -
Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing?.
Archives of neurology.
2006
Academic Article
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Times cited: 61 -
"Individual and health-related quality of life assessment in amyotrophic lateral sclerosis patients and their caregivers" by Lo Coco G, Lo Coco D, Cicero V, Oliveri A, Lo Verso G, Piccolo F, La Bella V.
Journal of the neurological sciences.
2005
Editorial Article
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Times cited: 2 -
Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism.
Journal of neuropathology and experimental neurology.
2004
Academic Article
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Times cited: 125 -
Design using historical controls.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases.
2004
Academic Article
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Times cited: 2 -
Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden.
Neurology.
2004
Academic Article
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Times cited: 217 -
HFE mutations are not strongly associated with sporadic ALS.
Neurology.
2004
Academic Article
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Times cited: 38 -
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue.
Annals of neurology.
2004
Academic Article
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Times cited: 387 -
Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis.
Current opinion in rheumatology.
2003
Information Resource
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Times cited: 86 -
PARP expression is increased in astrocytes but decreased in motor neurons in the spinal cord of sporadic ALS patients.
Journal of neuropathology and experimental neurology.
2003
Academic Article
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Times cited: 47 -
Mechanisms of disease pathogenesis in amyotrophic lateral sclerosis. A central role for calcium.
Advances in neurology.
2002
Information Resource
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Times cited: 12 -
Activated microglia: the silent executioner in neurodegenerative disease?.
Current neurology and neuroscience reports.
2001
Information Resource
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Times cited: 16