Luciani, Fabio

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Progenitor effects and unique transcriptomic signatures linked to differentiation phenotype in clonally expanded antigen-specific CD8 T memory stem cells. Journal of immunology (Baltimore, Md. : 1950). 2025 Academic Article GET IT
Human axillary lymph node T follicular helper (Tfh) and Precursor-Tfh cells exhibit functional flexibility following seasonal influenza vaccination. Clinical & translational immunology. 2025 Academic Article GET IT
Refractory coeliac disease or something else?. Pathology. 2025 Letter GET IT
Expanded CD16⁺CD56⁺Granzyme B⁺ NK like CD8⁺ T cells an off target effect of bruton's tyrosine kinase inhibitors in Waldenström macroglobulinemia. Scientific reports. 2025 Academic Article GET IT
Temporal dynamics of viral fitness and the adaptive immune response in HCV infection. eLife. 2025 Academic Article GET IT
Central memory T cells with key TCR repertoires and gene expression profiles dominate influenza CD8+ T cell pools across the human lifespan. Proceedings of the National Academy of Sciences of the United States of America. 2025 Academic Article GET IT
Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease. Science translational medicine. 2025 Academic Article GET IT
Times cited: 3
Advancing CAR T-cell Therapies with Artificial Intelligence: Opportunities and Challenges. Blood cancer discovery. 2025 Review GET IT
Times cited: 6
A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease. Immunity. 2025 Academic Article GET IT
Times cited: 4
Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma. Nature communications. 2024 Academic Article GET IT
Times cited: 4
Identification of clonally expanded γδ T-cell populations during CAR-T cell therapy. Immunology and cell biology. 2024 Academic Article GET IT
Times cited: 1
Discovery of a monoclonal, high-affinity CD8⁺ T-cell clone following natural hepatitis C virus infection. Immunology and cell biology. 2024 Academic Article GET IT
The CD8⁺ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects. Immunity. 2024 Academic Article GET IT
Times cited: 9
A novel network-based method identifies a cuproplasia-related pan-cancer gene signature to predict patient outcome. Human genetics. 2024 Academic Article GET IT
B-cell characteristics define HCV reinfection outcome. Journal of hepatology. 2024 Academic Article GET IT
Times cited: 8
In-depth profiling of tumor tissue derived from malignant pleural mesothelioma patients identifies potential biomarkers predicting response to immune-checkpoint inhibitor therapy. Genes & diseases. 2023 Academic Article GET IT
CAR⁺ and CAR^- T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies. Nature communications. 2023 Academic Article GET IT
Times cited: 25
Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance. Cancers. 2023 Academic Article GET IT
Times cited: 5
Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach. Nature immunology. 2023 Academic Article GET IT
Times cited: 24
Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan. Nature immunology. 2023 Academic Article GET IT
Times cited: 20
A conversation on allergy: recognizing the past and looking to the future. Immunology and cell biology. 2023 Academic Article GET IT
Times cited: 3
Identification of human progenitors of exhausted CD8⁺ T cells associated with elevated IFN-γ response in early phase of viral infection. Nature communications. 2022 Academic Article GET IT
Times cited: 21
High activation levels maintained in receptor-binding domain-specific memory B cells in people with severe coronavirus disease 2019. Immunology and cell biology. 2022 Academic Article GET IT
Times cited: 5
VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2. Nature methods. 2022 Letter GET IT
Times cited: 115
Haematopoietic Stem Cell Transplantation Results in Extensive Remodelling of the Clonal T Cell Repertoire in Multiple Sclerosis. Frontiers in immunology. 2022 Academic Article GET IT
Times cited: 18
CD8⁺ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nature communications. 2021 Academic Article GET IT
Times cited: 33
Antigen-driven EGR2 expression is required for exhausted CD8⁺ T cell stability and maintenance. Nature communications. 2021 Academic Article GET IT
Times cited: 35
One year into the pandemic: Short-term evolution of SARS-CoV-2 and emergence of new lineages. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2021 Review GET IT
Times cited: 50
Human CD8 T-stem cell memory subsets phenotypic and functional characterization are defined by expression of CD122 or CXCR3. European journal of immunology. 2021 Academic Article GET IT
Times cited: 9
Natural killer cell receptors regulate responses of HLA-E-restricted T cells. Science immunology. 2021 Academic Article GET IT
Times cited: 19
Prophylactic antigen-specific T-cells targeting seven viral and fungal pathogens after allogeneic haemopoietic stem cell transplant. Clinical & translational immunology. 2021 Academic Article GET IT
Times cited: 36
Hepatitis C treatment strategies in prisons: A cost-effectiveness analysis. PloS one. 2021 Academic Article GET IT
Times cited: 14
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans. Cell reports. 2021 Academic Article GET IT
Times cited: 144
Omics in immunology. Immunology and cell biology. 2021 Editorial Article GET IT
Recent advances in single-cell multimodal analysis to study immune cells. Immunology and cell biology. 2021 Review GET IT
Times cited: 9
Quantitative analysis of the splice variants expressed by the major hepatitis B virus genotypes. Microbial genomics. 2021 Academic Article GET IT
Times cited: 28
Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis. Nature communications. 2020 Academic Article GET IT
Times cited: 204
Conserved epitopes with high HLA-I population coverage are targets of CD8⁺ T cells associated with high IFN-γ responses against all dengue virus serotypes. Scientific reports. 2020 Academic Article GET IT
Times cited: 8
Cytotoxic T cells swarm by homotypic chemokine signalling. eLife. 2020 Academic Article GET IT
Times cited: 69
SARS-CoV-2 and COVID-19: A genetic, epidemiological, and evolutionary perspective. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2020 Review GET IT
Times cited: 108
Exploring and analysing single cell multi-omics data with VDJView. BMC medical genomics. 2020 Academic Article GET IT
Times cited: 18
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody. Cell. 2020 Academic Article GET IT
Times cited: 104
VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium. Nucleic acids research. 2020 Academic Article GET IT
Times cited: 270
B cell immunodominance in primary hepatitis C virus infection. Journal of hepatology. 2019 Academic Article GET IT
Times cited: 27
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. Nature communications. 2019 Academic Article GET IT
Times cited: 207
Genomic characterization of hepatitis C virus transmitted founder variants with deep sequencing. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2019 Academic Article GET IT
Times cited: 17
Human CD8⁺ T cell cross-reactivity across influenza A, B and C viruses. Nature immunology. 2019 Academic Article GET IT
Times cited: 192
Higher abundance of enterovirus A species in the gut of children with islet autoimmunity. Scientific reports. 2019 Academic Article GET IT
Times cited: 44
Genomic variability of within-host hepatitis C variants in acute infection. Journal of viral hepatitis. 2019 Academic Article GET IT
Times cited: 6
Single-Cell Transcriptome Analysis of T Cells. Methods in molecular biology (Clifton, N.J.). 2019 Academic Article GET IT
Times cited: 2
Dynamic interactions between RNA viruses and human hosts unravelled by a decade of next generation sequencing. Biochimica et biophysica acta. General subjects. 2018 Review GET IT
Times cited: 3
Understanding the Determinants of BnAb Induction in Acute HCV Infection. Viruses. 2018 Academic Article GET IT
Times cited: 16
Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes. Nature communications. 2018 Academic Article GET IT
Times cited: 88
B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle. Bioinformatics (Oxford, England). 2018 Academic Article GET IT
Times cited: 75
Amplification and next generation sequencing of near full-length human enteroviruses for identification and characterisation from clinical samples. Scientific reports. 2018 Academic Article GET IT
Times cited: 27
Clonally diverse CD38⁺HLA-DR⁺CD8⁺ T cells persist during fatal H7N9 disease. Nature communications. 2018 Academic Article GET IT
Times cited: 101
Longitudinal injecting risk behaviours among people with a history of injecting drug use in an Australian prison setting: The HITS-p study. The International journal on drug policy. 2018 Academic Article GET IT
Times cited: 58
Impact of sequencing depth and read length on single cell RNA sequencing data of T cells. Scientific reports. 2017 Academic Article GET IT
Times cited: 55
A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment. Immunity. 2017 Academic Article GET IT
Times cited: 203
Influence of Transmitted Virus on the Host's Immune Response: A Case Study. 2017 GET IT
Times cited: 1
Ongoing incident hepatitis C virus infection among people with a history of injecting drug use in an Australian prison setting, 2005-2014: The HITS-p study. Journal of viral hepatitis. 2017 Academic Article GET IT
Times cited: 70
Dynamic evolution of hepatitis C virus resistance-associated substitutions in the absence of antiviral treatment. Scientific reports. 2017 Academic Article GET IT
Times cited: 15
Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2017 Academic Article GET IT
Times cited: 10
Understanding the complex evolution of rapidly mutating viruses with deep sequencing: Beyond the analysis of viral diversity. Virus research. 2016 Review GET IT
Times cited: 18
Accumulation of Deleterious Passenger Mutations Is Associated with the Progression of Hepatocellular Carcinoma. PloS one. 2016 Academic Article GET IT
Times cited: 14
Historical Trends in the Hepatitis C Virus Epidemics in North America and Australia. The Journal of infectious diseases. 2016 Academic Article GET IT
Times cited: 15
Single-Molecule Sequencing Reveals Complex Genome Variation of Hepatitis B Virus during 15 Years of Chronic Infection following Liver Transplantation. Journal of virology. 2016 Academic Article GET IT
Times cited: 39
Incident Hepatitis C Virus Genotype Distribution and Multiple Infection in Australian Prisons. Journal of clinical microbiology. 2016 Academic Article GET IT
Times cited: 16
HCV RNA traffic and association with NS5A in living cells. Virology. 2016 Academic Article GET IT
Times cited: 9
A method for near full-length amplification and sequencing for six hepatitis C virus genotypes. BMC genomics. 2016 Academic Article GET IT
Times cited: 56
Linking the T cell receptor to the single cell transcriptome in antigen-specific human T cells. Immunology and cell biology. 2016 Academic Article GET IT
Times cited: 100
Natural killer cells in highly exposed hepatitis C-seronegative injecting drug users. Journal of viral hepatitis. 2016 Academic Article GET IT
Times cited: 4

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Background

education and training

B.S., Federico II University (Italy) 96
Ph.D., Humboldt University (Germany) 2006
M.Sc., University of Bologna (Italy) 2000

Contact

full name

Fabio Luciani

primary email

fal4003@med.cornell.edu

VIVO Weill Cornell Medical College

Fabio Luciani Visiting Assistant Professor of Systems and Computational Biomedicine

Publications

selected publications

Background

education and training

Contact

full name

primary email