selected publications Gold nanorod-assisted theranostic solution for nonvisible residual disease in bladder cancer. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT Topographic modification of the extracellular matrix precedes the onset of bladder cancer. Matrix biology plus. 2024 Academic Article GET IT Distinct mesenchymal cell states mediate prostate cancer progression. Nature communications. 2024 Academic Article GET IT Stool Microbiome Signature Associated with Response to Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Cancer. European urology. 2024 Academic Article GET IT Progressive alteration of murine bladder elasticity in actinic cystitis detected by Brillouin microscopy. Scientific reports. 2024 Academic Article GET IT Whole exome data prioritization unveils the hidden weight of Mendelian causes of male infertility. A report from the first Italian cohort. PloS one. 2023 Academic Article GET IT Predicting Limited Survival Following Inguinal Lymph Node Dissection in Penile Cancer: Should we revisit the goals of care?. Urology. 2023 Academic Article GET IT Micro-mechanical fingerprints of the rat bladder change in actinic cystitis and tumor presence. Communications biology. 2023 Academic Article GET IT Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castration-resistant prostate cancer. Journal of translational medicine. 2023 Academic Article GET IT Concomitant vs Staged Therapeutic Inguinal Lymphadenectomy in Clinically Node Positive Penile Squamous Cell Carcinoma: Does It Make a Difference?. The Journal of urology. 2023 Academic Article GET IT "Stromal cells in prostate cancer pathobiology: friends or foes?". British journal of cancer. 2022 Review GET IT Circulating Cell-Free DNA in Renal Cell Carcinoma: The New Era of Precision Medicine. Cancers. 2022 Review GET IT Early diagnosis of bladder cancer by photoacoustic imaging of tumor-targeted gold nanorods. Photoacoustics. 2022 Academic Article GET IT Efficacy and toxicity of antibody-drug conjugates in the treatment of metastatic urothelial cancer: A scoping review. Urologic oncology. 2022 Review GET IT The Pros and Cons of "Machination of Medicine" in Genitourinary Oncology Practice. Bladder cancer (Amsterdam, Netherlands). 2022 Editorial Article GET IT A global approach to improving penile cancer care. Nature reviews. Urology. 2021 Review GET IT Bladder-sparing combination treatments for muscle-invasive bladder cancer: A plea for standardized assessment and definition of clinical trials endpoints. Urologic oncology. 2021 Review GET IT Risk factors and survival outcomes for upstaging after inguinal lymph node dissection for cN1 penile squamous cell carcinoma. Urologic oncology. 2021 Academic Article GET IT Risk of health status worsening in primary infertile men: A prospective 10-year follow-up study. Andrology. 2021 Academic Article GET IT Times cited: 3 Aging, inflammation and DNA damage in the somatic testicular niche with idiopathic germ cell aplasia. Nature communications. 2021 Academic Article GET IT Times cited: 36 Testicular volume in infertile versus fertile white-European men: a case-control investigation in the real-life setting. Asian journal of andrology. 2021 Academic Article GET IT Times cited: 28 Causal contributors to tissue stiffness and clinical relevance in urology. Communications biology. 2021 Review GET IT Times cited: 38 Reply by Authors. The Journal of urology. 2021 Comment GET IT Clinical Outcomes of Patients With Metastatic Urothelial Carcinoma After Progression to Immune Checkpoint Inhibitors: A Retrospective Analysis by the Meet-Uro Group (Meet-URO 1 Study). Clinical Medicine Insights. Oncology. 2021 Academic Article GET IT A feasibility study of preoperative pembrolizumab before radical nephroureterectomy in patients with high-risk, upper tract urothelial carcinoma: PURE-02. Urologic oncology. 2021 Academic Article GET IT Times cited: 2 High-risk Surgically Resected Renal Cell Carcinoma: Is There a Role for Adjuvant VEGF-TKI Inhibitors?. Current problems in cancer. 2021 Review GET IT Is There a Detrimental Effect of Antibiotic Therapy in Patients with Muscle-invasive Bladder Cancer Treated with Neoadjuvant Pembrolizumab?. European urology. 2021 Academic Article GET IT Times cited: 4 Patterns of Recurrence following Inguinal Lymph Node Dissection for Penile Cancer: Optimizing Surveillance Strategies. The Journal of urology. 2021 Academic Article GET IT Times cited: 1 Intermediate- and high-risk nonmuscle invasive bladder cancer: Where do we stand?. Urologic oncology. 2021 Review GET IT Times cited: 1 Predicting the Pathologic Complete Response After Neoadjuvant Pembrolizumab in Muscle-Invasive Bladder Cancer. Journal of the National Cancer Institute. 2021 Academic Article GET IT Times cited: 31 Perioperative and oncologic outcomes of open radical nephrectomy and inferior vena cava thrombectomy with liver mobilization and Pringle maneuver for Mayo III level tumor thrombus: single institution experience. Minerva urology and nephrology. 2020 Academic Article GET IT Times cited: 1 Association Between Human Papillomavirus Infection and Outcome of Perioperative Nodal Radiotherapy for Penile Carcinoma. European urology oncology. 2020 Academic Article GET IT Times cited: 3 Incidence and Clinical Impact of Inflammatory Fluorodeoxyglucose Positron Emission Tomography Uptake After Neoadjuvant Pembrolizumab in Patients with Organ-confined Bladder Cancer Undergoing Radical Cystectomy. European urology focus. 2020 Academic Article GET IT Times cited: 2 Normal sperm parameters per se do not reliably account for fertility: A case-control study in the real-life setting. Andrologia. 2020 Academic Article GET IT Times cited: 5 [18F]Fluoro-Deoxy-Glucose positron emission tomography to evaluate lymph node involvement in patients with muscle-invasive bladder cancer receiving neoadjuvant pembrolizumab. Urologic oncology. 2020 Academic Article GET IT Times cited: 3 Targetable gene fusions and aberrations in genitourinary oncology. Nature reviews. Urology. 2020 Review GET IT Times cited: 13 Does the administration of preoperative pembrolizumab lead to sustained remission post-cystectomy? First survival outcomes from the PURE-01 study☆. Annals of oncology : official journal of the European Society for Medical Oncology. 2020 Academic Article GET IT Times cited: 17 Contemporary Treatment Patterns and Outcomes for Patients with Penile Squamous Cell Carcinoma: Identifying Management Gaps to Promote Multi-institutional Collaboration. European urology oncology. 2020 Letter GET IT Times cited: 2 Re: Siamak Daneshmand, Azadeh Nazemi. Neoadjuvant Chemotherapy in Variant Histology Bladder Cancer: Current Evidence. Eur Urol Focus 2020;6:639-41. European urology focus. 2020 Letter GET IT Infertile Men Have Higher Prostate-specific Antigen Values than Fertile Individuals of Comparable Age. European urology. 2020 Academic Article GET IT Times cited: 3 A risk calculator predicting recurrence in lymph node metastatic penile cancer. BJU international. 2020 Academic Article GET IT Times cited: 7 The new era of precision urobiome: RE: "Characterization of urinary microbiome in patients with bladder cancer: Results from a single-institution, feasibility study" by Chipollini et al. Urologic oncology. 2020 Letter GET IT The Value of Multiparametric Magnetic Resonance Imaging Sequences to Assist in the Decision Making of Muscle-invasive Bladder Cancer. European urology oncology. 2020 Academic Article GET IT Times cited: 6 Can Patients with Muscle-invasive Bladder Cancer and Fibroblast Growth Factor Receptor-3 Alterations Still Be Considered for Neoadjuvant Pembrolizumab? A Comprehensive Assessment from the Updated Results of the PURE-01 Study. European urology oncology. 2020 Academic Article GET IT Times cited: 4 Sex-specific Alterations in the Urinary and Tissue Microbiome in Therapy-naïve Urothelial Bladder Cancer Patients. European urology oncology. 2020 Academic Article GET IT Times cited: 11 Semen infections in men with primary infertility in the real-life setting. Fertility and sterility. 2020 Academic Article GET IT Times cited: 10 Optimising the selection of candidates for neoadjuvant chemotherapy amongst patients with node-positive penile squamous cell carcinoma. BJU international. 2020 Academic Article GET IT Times cited: 7 Impact of Molecular Subtyping and Immune Infiltration on Pathological Response and Outcome Following Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer. European urology. 2020 Academic Article GET IT Times cited: 51 Neoadjuvant chemotherapy for lymph node-positive penile cancer: current evidence and knowledge. Current opinion in urology. 2020 Review GET IT Times cited: 1 Unfavorable Cancer-specific Survival After Neoadjuvant Chemotherapy and Radical Cystectomy in Patients With Bladder Cancer and Squamous Cell Variant: A Multi-institutional Study. Clinical genitourinary cancer. 2020 Academic Article GET IT Times cited: 18 Multiparametric Magnetic Resonance Imaging as a Noninvasive Assessment of Tumor Response to Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer: Preliminary Findings from the PURE-01 Study. European urology. 2019 Academic Article GET IT Times cited: 38 Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies. European urology. 2019 Academic Article GET IT Times cited: 107 Editorial Comment. The Journal of urology. 2019 Comment GET IT Heavy cigarette smoking and alcohol consumption are associated with impaired sperm parameters in primary infertile men. Asian journal of andrology. 2019 Academic Article GET IT Times cited: 67 Incremental Utility of Adjuvant Chemotherapy in Muscle-invasive Bladder Cancer: Quantifying the Relapse Risk Associated with Therapeutic Effect. European urology. 2019 Academic Article GET IT Times cited: 13 Regenerative and engineered options for urethroplasty. Nature reviews. Urology. 2019 Review GET IT Times cited: 14 Diagnosis of urothelial carcinoma in situ using blue light cystoscopy and the utility of immunohistochemistry in blue light-positive lesions diagnosed as atypical. Human pathology. 2019 Academic Article GET IT Times cited: 7 Impaired testicular signaling of vitamin A and vitamin K contributes to the aberrant composition of the extracellular matrix in idiopathic germ cell aplasia. Fertility and sterility. 2019 Academic Article GET IT Times cited: 9 High-risk human papillomavirus in semen is associated with poor sperm progressive motility and a high sperm DNA fragmentation index in infertile men. Human reproduction (Oxford, England). 2019 Academic Article GET IT Times cited: 28 Impact of intravesical therapy for non-muscle invasive bladder cancer on the accuracy of urine cytology. World journal of urology. 2019 Academic Article GET IT Times cited: 6 The duration of infertility affects semen parameters in primary infertile men: results of a single-centre, cross-sectional study. BJU international. 2018 Academic Article GET IT Times cited: 4 Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate. Molecular cancer research : MCR. 2018 Academic Article GET IT Times cited: 46 Undiagnosed prediabetes is highly prevalent in primary infertile men - results from a cross-sectional study. BJU international. 2018 Academic Article GET IT Times cited: 11 Clinical Profile of Young Patients with Erectile Dysfunction: Preliminary Findings of a Real-life Cross-sectional Study. European urology focus. 2018 Academic Article GET IT Times cited: 7 Multiple PDE5Is use as a marker of decreased overall men's health: A real-life study. PloS one. 2018 Academic Article GET IT High Blood Pressure Is a Highly Prevalent but Unrecognised Condition in Primary Infertile Men: Results of a Cross-sectional Study. European urology focus. 2018 Academic Article GET IT Times cited: 15 Unrecognized Prediabetes Is Highly Prevalent in Men With Erectile Dysfunction-Results From a Cross-Sectional Study. The journal of sexual medicine. 2018 Academic Article GET IT Times cited: 7 The role of neutrophil-to-lymphocyte ratio in men with erectile dysfunction-preliminary findings of a real-life cross-sectional study. Andrology. 2018 Academic Article GET IT Times cited: 10 Age at First Presentation for Erectile Dysfunction: Analysis of Changes over a 12-yr Period. European urology focus. 2018 Academic Article GET IT Times cited: 11 Surgical Factors Associated With Male and Female Sexual Dysfunction After Radical Cystectomy: What Do We Know and How Can We Improve Outcomes?. Sexual medicine reviews. 2018 Review GET IT Times cited: 13 Anti-Mullerian Hormone-to-Testosterone Ratio is Predictive of Positive Sperm Retrieval in Men with Idiopathic Non-Obstructive Azoospermia. Scientific reports. 2017 Academic Article GET IT Times cited: 44 Does Calculated Free Testosterone Overcome Total Testosterone in Protecting From Sexual Symptom Impairment? Findings of a Cross-Sectional Study. The journal of sexual medicine. 2017 Academic Article GET IT Times cited: 6 Long-term penile morphometric alterations in patients treated with robot-assisted versus open radical prostatectomy. Andrology. 2017 Academic Article GET IT Times cited: 5 Clinically Meaningful Improvements in LUTS/BPH Severity in Men Treated with Silodosin Plus Hexanic Extract of Serenoa Repens or Silodosin Alone. Scientific reports. 2017 Academic Article GET IT Times cited: 16 Oncological Outcomes of Sequential Intravesical Gemcitabine and Docetaxel in Patients with Non-Muscle Invasive Bladder Cancer. Bladder cancer (Amsterdam, Netherlands). 2017 Academic Article GET IT Times cited: 65 Depressive Symptoms and Low Sexual Desire after Radical Prostatectomy: Early and Long-Term Outcomes in a Real-Life Setting. The Journal of urology. 2017 Academic Article GET IT Times cited: 17 Analysis of Hospital Readmissions After Prosthetic Urologic Surgery in the United States: Nationally Representative Estimates of Causes, Costs, and Predictive Factors. The journal of sexual medicine. 2017 Academic Article GET IT Times cited: 2 Primary, secondary and compensated hypogonadism: a novel risk stratification for infertile men. Andrology. 2017 Academic Article GET IT Times cited: 23 Sexual functioning mirrors overall men's health status, even irrespective of cardiovascular risk factors. Andrology. 2017 Academic Article GET IT Times cited: 15 When to Perform Karyotype Analysis in Infertile Men? Validation of the European Association of Urology Guidelines with the Proposal of a New Predictive Model. European urology. 2016 Academic Article GET IT Times cited: 28
Funding awarded Loss of Stromal Androgen Receptor (AR) Signaling Contributes to Progression in Prostate Cancer Principal Investigator 2023 - 2024 missing activity Principal Investigator 2022 - 2024
outreach and community service activities Postdoctoral Association (PDA), Weill Cornell Medicine Member, Science Outreach Committee 2022 - 2023
education and training Ph.D., San Raffaele University (Italy) 21 M.D., San Raffaele University School of Medicine(Italy) 2017
awards and honors Resident Corner Award, conferred by European Urology, the official journal of the European Association of Urology (EAU), 2022 Conquer Cancer Annual Meeting Merit Award, conferred by ASCO (American Society of Clinical Oncology) Foundation, 2021 Cancer Immunotherapy Winter School Travel Award, conferred by Society for Immunotherapy of Cancer (SITC), 2021 Simona Morone Prize, conferred by Fondazione Ricerca Molinette Onlus, Associazione “Guarda oltre ciò che vedi”, 2020