Abou-Alfa, Ghassan

Publications

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selected publications

Phase II trial of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma after disease progression on sorafenib. Cancer medicine. 2020 Academic Article GET IT
Times cited: 11
Ivosidenib for advanced IDH1-mutant cholangiocarcinoma - Authors' reply. The Lancet. Oncology. 2020 Article GET IT
Molecular profiling and analysis of genetic aberrations aimed at identifying potential therapeutic targets in fibrolamellar carcinoma of the liver. Cancer. 2020 Academic Article GET IT
Phase Ib Study of Enzalutamide with or Without Sorafenib in Patients with Advanced Hepatocellular Carcinoma. The oncologist. 2020 Academic Article GET IT
Times cited: 12
A Multicenter Randomized Three-Arm Phase II Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) with Leuprolide + Letrozole, and (3) Everolimus + EDT in Patients with Unresectable Fibrolamellar Carcinoma. The oncologist. 2020 Academic Article GET IT
Times cited: 20
Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 138
Comparative Efficacy of Cabozantinib and Regorafenib for Advanced Hepatocellular Carcinoma. Advances in therapy. 2020 Academic Article GET IT
Times cited: 37
Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study. The Lancet. Oncology. 2020 Academic Article GET IT
Times cited: 209
Germline alterations in patients with biliary tract cancers: A spectrum of significant and previously underappreciated findings. Cancer. 2020 Academic Article GET IT
Times cited: 33
Assessment of Treatment With Sorafenib Plus Doxorubicin vs Sorafenib Alone in Patients With Advanced Hepatocellular Carcinoma: Phase 3 CALGB 80802 Randomized Clinical Trial. JAMA oncology. 2019 Academic Article GET IT
Times cited: 81
Gallbladder cancer, a forgotten global cancer problem. Chinese clinical oncology. 2019 Editorial Article GET IT
Biliary tract cancer prognostic and predictive genomics. Chinese clinical oncology. 2019 Academic Article GET IT
Times cited: 15
Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: a phase 1 study. The lancet. Gastroenterology & hepatology. 2019 Academic Article GET IT
Times cited: 165
A Phase Ib/II Study of Ramucirumab in Combination with Emibetuzumab in Patients with Advanced Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 10
Ramucirumab and the controversial role of α-fetoprotein in hepatocellular carcinoma. The Lancet. Oncology. 2019 Article GET IT
Times cited: 4
Systemic Therapy for Advanced Hepatocellular Carcinoma in an Evolving Landscape. Current treatment options in oncology. 2019 Information Resource GET IT
Times cited: 21
Binimetinib plus Gemcitabine and Cisplatin Phase I/II Trial in Patients with Advanced Biliary Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 25
Regional differences in gallbladder cancer pathogenesis: Insights from a multi-institutional comparison of tumor mutations. Cancer. 2018 Academic Article GET IT
Times cited: 39
A Phase Ib, Open-Label Study of Dalantercept, an Activin Receptor-Like Kinase 1 Ligand Trap, plus Sorafenib in Advanced Hepatocellular Carcinoma. The oncologist. 2018 Academic Article GET IT
Times cited: 13
Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms. Journal of the National Cancer Institute. 2018 Academic Article GET IT
Times cited: 180
Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma. The New England journal of medicine. 2018 Academic Article GET IT
Times cited: 1691
A phase 1 study of ADI-PEG 20 and modified FOLFOX6 in patients with advanced hepatocellular carcinoma and other gastrointestinal malignancies. Cancer chemotherapy and pharmacology. 2018 Academic Article GET IT
Times cited: 34
Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology. 2018 Academic Article GET IT
Times cited: 86
Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 377
Biomarker-Driven and Molecular Targeted Therapies for Hepatobiliary Cancers. Seminars in oncology. 2018 Information Resource GET IT
Times cited: 6
Brain Metastases in Pancreatic Ductal Adenocarcinoma: Assessment of Molecular Genotype-Phenotype Features-An Entity With an Increasing Incidence?. Clinical colorectal cancer. 2018 Academic Article GET IT
Times cited: 13
Frequency, Morbidity, and Mortality of Bone Metastases in Advanced Hepatocellular Carcinoma. Journal of the National Comprehensive Cancer Network : JNCCN. 2018 Academic Article GET IT
Times cited: 16
Phase II Study of BGJ398 in Patients With FGFR-Altered Advanced Cholangiocarcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2017 Academic Article GET IT
Times cited: 543
A phase 1/1B trial of ADI-PEG 20 plus nab-paclitaxel and gemcitabine in patients with advanced pancreatic adenocarcinoma. Cancer. 2017 Academic Article GET IT
Times cited: 33
Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 80
Phase II Study of First-Line Trebananib Plus Sorafenib in Patients with Advanced Hepatocellular Carcinoma. The oncologist. 2017 Academic Article GET IT
Times cited: 17
An elderly man with remote history of metastatic melanoma now with localized pancreas cancer and new liver masses. 2017 GET IT
Pharmacokinetics and safety of vismodegib in patients with advanced solid malignancies and hepatic impairment. Cancer chemotherapy and pharmacology. 2017 Academic Article GET IT
Times cited: 23
Cabozantinib: targeted therapy back to the future?. Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Editorial Article GET IT
Times cited: 1
Phase Ib study of codrituzumab in combination with sorafenib in patients with non-curable advanced hepatocellular carcinoma (HCC). Cancer chemotherapy and pharmacology. 2017 Academic Article GET IT
Times cited: 22
Hepatocellular carcinoma in patients with HIV. Current opinion in HIV and AIDS. 2017 Information Resource GET IT
Times cited: 12
Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference. Journal of gastrointestinal oncology. 2016 Academic Article GET IT
Times cited: 16
Hepatocellular adenoma among adult survivors of childhood and young adult cancer. Pediatric blood & cancer. 2016 Academic Article GET IT
Times cited: 7
Reply to A. Braillon, M. Boulin et al, and J.-H. Zhong et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Letter GET IT
Biliary carcinomas: pathology and the role of DNA mismatch repair deficiency. Chinese clinical oncology. 2016 Information Resource GET IT
Times cited: 69
Combined intrahepatic cholangiocarcinoma and hepatocellular carcinoma. Chinese clinical oncology. 2016 Information Resource GET IT
Times cited: 18
Advanced Hepatocellular Cancer: the Current State of Future Research. Current treatment options in oncology. 2016 Information Resource GET IT
Times cited: 37
A Review and Update of Treatment Options and Controversies in the Management of Hepatocellular Carcinoma. Annals of surgery. 2016 Information Resource GET IT
Times cited: 139
Randomized phase II placebo controlled study of codrituzumab in previously treated patients with advanced hepatocellular carcinoma. Journal of hepatology. 2016 Academic Article GET IT
Times cited: 58
Randomized Trial of Hepatic Artery Embolization for Hepatocellular Carcinoma Using Doxorubicin-Eluting Microspheres Compared With Embolization With Microspheres Alone. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 299
Immunotherapy in hepatocellular carcinoma: Primed to make a difference?. Cancer. 2015 Information Resource GET IT
Times cited: 90
"This is not me": patient, family, cultural and clinician considerations in cases of severe cancer-related debility. Journal of gastrointestinal oncology. 2015 Academic Article GET IT
Liver resection for metastatic colorectal leiomyosarcoma: a single center experience. Journal of gastrointestinal oncology. 2015 Academic Article GET IT
Times cited: 15
Liver-directed conversion therapy in metastatic colon cancer. Journal of gastrointestinal oncology. 2015 Academic Article GET IT
Times cited: 2
Locoregional Therapy for Hepatocellular Carcinoma with and without Extrahepatic Spread. Journal of vascular and interventional radiology : JVIR. 2015 Academic Article GET IT
Times cited: 5
Hospitalists on an inpatient tertiary care oncology teaching service. Journal of oncology practice. 2015 Academic Article GET IT
Times cited: 8
Hepatocellular carcinoma tumor board: making sense of the technologies. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. 2015 Information Resource GET IT
Times cited: 1
Pharmacogenomic modeling of circulating tumor and invasive cells for prediction of chemotherapy response and resistance in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 51
A single-arm, nonrandomized phase II trial of neoadjuvant gemcitabine and oxaliplatin in patients with resectable pancreas adenocarcinoma. Annals of surgery. 2014 Academic Article GET IT
Times cited: 126
CT and MRI of primary and metastatic fibrolamellar carcinoma: a case series of 37 patients. The British journal of radiology. 2014 Academic Article GET IT
Times cited: 20
Treating advanced hepatocellular carcinoma: How to get out of first gear. Cancer. 2014 Information Resource GET IT
Times cited: 26
Challenges in combining antiangiogenic therapy with transarterial chemoembolization for hepatocellular carcinoma. Gastrointestinal cancer research : GCR. 2014 Academic Article GET IT
From the liver to the foot: a case of systemic embolism and acrometastasis in hepatocellular carcinoma. Gastrointestinal cancer research : GCR. 2014 Academic Article GET IT
Lymph node ratio is an independent prognostic factor after resection of periampullary malignancies: data from a tertiary referral center in the middle East. American journal of clinical oncology. 2014 Academic Article GET IT
Times cited: 13
A woman with metastatic pancreatic neuroendocrine tumor. Gastrointestinal cancer research : GCR. 2014 Academic Article GET IT
The role of tyrosine kinase inhibitors in hepatocellular carcinoma. Clinical advances in hematology & oncology : H&O. 2014 Academic Article GET IT
Times cited: 9
A phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma. Journal of hepatology. 2013 Academic Article GET IT
Times cited: 83
c-MET and HGF mRNA expression in hepatocellular carcinoma: correlation with clinicopathological features and survival. Anticancer research. 2013 Academic Article GET IT
Times cited: 13
A phase II study of gemcitabine and cisplatin plus sorafenib in patients with advanced biliary adenocarcinomas. British journal of cancer. 2013 Academic Article GET IT
Times cited: 107
Postoperative outcomes following pancreaticoduodenectomy: how should age affect clinical practice?. World journal of surgical oncology. 2013 Academic Article GET IT
Times cited: 20
A 40-year-old woman with locally advanced rectal cancer and a solitary liver metastasis. Gastrointestinal cancer research : GCR. 2013 Academic Article GET IT
Optimal chemotherapy dosing in a bilateral lower extremities amputee with metastatic pancreatic adenocarcinoma. 2013 GET IT
A randomized controlled trial of a cardiopulmonary resuscitation video in advance care planning for progressive pancreas and hepatobiliary cancer patients. Journal of palliative medicine. 2013 Academic Article GET IT
Times cited: 75
Management of a patient diagnosed with pancreatic cancer and myelodysplastic syndrome. Gastrointestinal cancer research : GCR. 2013 Academic Article GET IT
Skin necrosis induced by generic enoxaparin. American journal of hematology. 2013 Article GET IT
A young woman with liver cancer. Gastrointestinal cancer research : GCR. 2013 Academic Article GET IT
Clinicopathologic characteristics and survival outcomes of patients with fibrolamellar carcinoma: data from the fibrolamellar carcinoma consortium. Gastrointestinal cancer research : GCR. 2013 Academic Article GET IT
Targeted agents and systemic therapy in hepatocellular carcinoma. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 2013 Review GET IT
Times cited: 21
ACR Appropriateness Criteria radiologic management of hepatic malignancy. Journal of the American College of Radiology : JACR. 2012 Academic Article GET IT
Times cited: 3
A Nonrandomized, Phase II Study of Sequential Irinotecan and Flavopiridol in Patients With Advanced Hepatocellular Carcinoma. Gastrointestinal cancer research : GCR. 2012 Academic Article GET IT
Management of a locally advanced rectal cancer in a patient who declined surgery. Gastrointestinal cancer research : GCR. 2012 Academic Article GET IT
Neoadjuvant Therapy in Clinical Stage II Pancreatic Adenocarcinoma. Gastrointestinal cancer research : GCR. 2012 Academic Article GET IT
Communication and palliative care in a 64-year-old man with pancreatic adenocarcinoma. Gastrointestinal cancer research : GCR. 2012 Academic Article GET IT
A man with Klinefelter's syndrome and new abdominal distension: a discussion of evaluation and management. 2012 GET IT
Times cited: 1
A 72-year-old man with duodenal adenocarcinoma. Gastrointestinal cancer research : GCR. 2012 Academic Article GET IT
Lymph-node ratio is an independent prognostic factor in patients with stage III colorectal cancer: a retrospective study from the Middle East. World journal of surgical oncology. 2012 Academic Article GET IT
Times cited: 19
A case of advanced gastric cancer. 2012 GET IT
Gastrointestinal cancer educatinal case series: a 65 year-old female with locally advanced gastric cancer and a supraclavicular lymph node. 2012 GET IT
A 71-year-old man with a large cystic pancreatic mass. 2012 GET IT
A woman with remotely treated pancreas cancer and new abdominal pain: a discussion of evaluation and management. 2011 GET IT
MicroRNA, hypoxic stress and hepatocellular carcinoma: future directions. Journal of gastroenterology and hepatology. 2011 Editorial Article GET IT
Times cited: 1
TACE and sorafenib: a good marriage?. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Editorial Article GET IT
Times cited: 48
Gastrointestinal cancer educational case series: management of metastatic adenocarcinoma of unknown primary origin in a Ph+ ALL survivor. 2011 GET IT
Times cited: 1
Hepatocellular carcinoma following renal transplantation. Gastrointestinal cancer research : GCR. 2011 Academic Article GET IT
Doxorubicin and sorafenib for treatment of advanced hepatocellular cancer. Gastroenterology. 2011 Article GET IT
Times cited: 6
Targeting mutated K-ras in pancreatic adenocarcinoma using an adjuvant vaccine. American journal of clinical oncology. 2011 Academic Article GET IT
Times cited: 66
PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma. Cancer chemotherapy and pharmacology. 2011 Academic Article GET IT
Times cited: 19
Safety and Efficacy of Sorafenib in Patients with Hepatocellular Carcinoma (HCC) and Child-Pugh A versus B Cirrhosis. Gastrointestinal cancer research : GCR. 2011 Academic Article GET IT
A Cancer and Leukemia Group B phase II study of sunitinib malate in patients with previously treated metastatic pancreatic adenocarcinoma (CALGB 80603). The oncologist. 2010 Academic Article GET IT
Times cited: 64
Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial. JAMA. 2010 Academic Article GET IT
Times cited: 349
Clinical roundtable monograph. Integrating recent data in managing adverse events in the treatment of hepatocellular carcinoma. Clinical advances in hematology & oncology : H&O. 2010 Academic Article GET IT
Times cited: 2
Hepatocellular carcinoma in two patients with cardiac cirrhosis. 2010 GET IT
Times cited: 60
Nonoperative therapies for combined modality treatment of hepatocellular cancer: expert consensus statement. HPB : the official journal of the International Hepato Pancreato Biliary Association. 2010 Conference Paper GET IT
Times cited: 67
Advanced hepatocellular carcinoma: which staging systems best predict prognosis?. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010 Academic Article GET IT
Times cited: 280
Pancreatic islet cell carcinoma presenting with concurrent Cushing's and Zollinger-Ellison syndromes: case series and literature review. European journal of gastroenterology & hepatology. 2010 Review GET IT
Times cited: 6
Indications for neoadjuvant, adjuvant, and palliative chemotherapy in the treatment of biliary tract cancers. Surgical oncology clinics of North America. 2009 Review GET IT
Times cited: 3
Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009 Academic Article GET IT
Gallbladder cancer (GBC): 10-year experience at Memorial Sloan-Kettering Cancer Centre (MSKCC). Journal of surgical oncology. 2008 Academic Article GET IT
Times cited: 227
Intrahepatic cholangiocarcinoma: rising frequency, improved survival, and determinants of outcome after resection. Annals of surgery. 2008 Academic Article GET IT
Times cited: 540
New agents in hepatocellular carcinoma. Clinical advances in hematology & oncology : H&O. 2008 Academic Article GET IT
Times cited: 1
The impact of new data in the treatment of advanced hepatocellular carcinoma. Current oncology reports. 2008 Information Resource GET IT
Times cited: 28
Expanding the treatment options for hepatocellular carcinoma: combining transarterial chemoembolization with radiofrequency ablation. JAMA. 2008 Editorial Article GET IT
Times cited: 12
Identifying vulnerable older adults with cancer: integrating geriatric assessment into oncology practice. Journal of the American Geriatrics Society. 2007 Academic Article GET IT
Times cited: 119
Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Academic Article GET IT
Times cited: 246
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Academic Article GET IT
Times cited: 1063
Outcome of patients with fibrolamellar hepatocellular carcinoma. Cancer. 2006 Academic Article GET IT
Times cited: 150
A Phase II study of intravenous exatecan administered daily for 5 days, every 3 weeks to patients with biliary tract cancers. American journal of clinical oncology. 2005 Academic Article GET IT
Times cited: 10
Therapeutic implications of the new biology. Cancer journal (Sudbury, Mass.). 2000 Information Resource GET IT
Times cited: 10
Characteristics and displaceability of neurotensin binding sites in the rat cerebral cortex and corpus striatum. General pharmacology. 1989 Academic Article GET IT
Times cited: 1

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Background

education and training

M.D., American University of Beirut Faculty of Medicine (Lebanon) 1992
B.S., American University of Beirut (Lebanon) 1988

Contact

full name

Ghassan Abou-Alfa

VIVO Weill Cornell Medical College

Ghassan Abou-Alfa Professor of Medicine

Publications

selected publications

Background

education and training

Contact

full name

Phone

Publications

selected publications

Background

education and training

Contact

full name