Shen, Haifa

Publications

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selected publications

Retraction of the Research Article: "Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide" by Z. Hu, S. Nizzero, S. Goel, L. E. Hinkle, X. Wu, C. Li, M. Ferrari and H. Shen. Science advances. 2020 Academic Article GET IT
Sequential deconstruction of composite drug transport in metastatic breast cancer. Science advances. 2020 Academic Article GET IT
Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide. Science advances. 2020 Academic Article GET IT
Times cited: 2
Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles. Acta biomaterialia. 2019 Academic Article GET IT
Times cited: 4
Sensitizing non-small cell lung cancer to BCL-xL-targeted apoptosis. Cell death & disease. 2018 Academic Article GET IT
Times cited: 7
Chemotherapy Sensitizes Therapy-Resistant Cells to Mild Hyperthermia by Suppressing Heat Shock Protein 27 Expression in Triple-Negative Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 11
SMAD4 Gene Mutation Renders Pancreatic Cancer Resistance to Radiotherapy through Promotion of Autophagy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 24
Distribution of Glutathione-Stabilized Gold Nanoparticles in Feline Fibrosarcomas and Their Role as a Drug Delivery System for Doxorubicin-Preclinical Studies in a Murine Model. International journal of molecular sciences. 2018 Academic Article GET IT
Times cited: 5
DNA Thioaptamer with Homing Specificity to Lymphoma Bone Marrow Involvement. Molecular pharmaceutics. 2018 Academic Article GET IT
Times cited: 8
Engineering functional inorganic-organic hybrid systems: advances in siRNA therapeutics. Chemical Society reviews. 2018 Review GET IT
Times cited: 41
Cyclic cRGDfk peptide and Chlorin e6 functionalized silk fibroin nanoparticles for targeted drug delivery and photodynamic therapy. Biomaterials. 2018 Academic Article GET IT
Times cited: 44
A Novel DNA Aptamer for Dual Targeting of Polymorphonuclear Myeloid-derived Suppressor Cells and Tumor Cells. Theranostics. 2018 Academic Article GET IT
Times cited: 24
A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery. Scientific reports. 2017 Academic Article GET IT
Times cited: 51
Bone-targeting nanoparticle to co-deliver decitabine and arsenic trioxide for effective therapy of myelodysplastic syndrome with low systemic toxicity. Journal of controlled release : official journal of the Controlled Release Society. 2017 Academic Article GET IT
Times cited: 16
Enhancing cancer immunotherapy through nanotechnology-mediated tumor infiltration and activation of immune cells. Seminars in immunology. 2017 Review GET IT
Times cited: 16
Contribution of Kupffer cells to liposome accumulation in the liver. Colloids and surfaces. B, Biointerfaces. 2017 Academic Article GET IT
Times cited: 35
A Liposome Encapsulated Ruthenium Polypyridine Complex as a Theranostic Platform for Triple-Negative Breast Cancer. Nano letters. 2017 Academic Article GET IT
Times cited: 58
Multi-step encapsulation of chemotherapy and gene silencing agents in functionalized mesoporous silica nanoparticles. Nanoscale. 2017 Academic Article GET IT
Times cited: 36
Targeting Autocrine CCL5-CCR5 Axis Reprograms Immunosuppressive Myeloid Cells and Reinvigorates Antitumor Immunity. Cancer research. 2017 Academic Article GET IT
Times cited: 42
Lipopolyplex potentiates anti-tumor immunity of mRNA-based vaccination. Biomaterials. 2017 Academic Article GET IT
Times cited: 39
Post-nano strategies for drug delivery: Multistage porous silicon microvectors. Journal of materials chemistry. B. 2016 Review GET IT
Times cited: 32
Strategies for improving drug delivery: nanocarriers and microenvironmental priming. Expert opinion on drug delivery. 2016 Review GET IT
Times cited: 18
Enzyme-responsive multistage vector for drug delivery to tumor tissue. Pharmacological research. 2016 Academic Article GET IT
Times cited: 35
A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells. Pharmacological research. 2016 Academic Article GET IT
Times cited: 6
Theory and Experimental Validation of a Spatio-temporal Model of Chemotherapy Transport to Enhance Tumor Cell Kill. PLoS computational biology. 2016 Academic Article GET IT
Times cited: 34
An injectable nanoparticle generator enhances delivery of cancer therapeutics. Nature biotechnology. 2016 Academic Article GET IT
Times cited: 174
E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis. Scientific reports. 2016 Academic Article GET IT
Times cited: 68
A Micro/Nano Composite for Combination Treatment of Melanoma Lung Metastasis. Advanced healthcare materials. 2016 Academic Article GET IT
Times cited: 32
Effective Concentration of a Multikinase Inhibitor within Bone Marrow Correlates with In Vitro Cell Killing in Therapy-Resistant Chronic Myeloid Leukemia. Molecular cancer therapeutics. 2016 Academic Article GET IT
Times cited: 3
Hesperetin Liposomes for Cancer Therapy. Current drug delivery. 2016 Academic Article GET IT
Times cited: 16
Radio-photothermal therapy mediated by a single compartment nanoplatform depletes tumor initiating cells and reduces lung metastasis in the orthotopic 4T1 breast tumor model. Nanoscale. 2015 Academic Article GET IT
Times cited: 51
Multistage vector delivery of sulindac and silymarin for prevention of colon cancer. Colloids and surfaces. B, Biointerfaces. 2015 Academic Article GET IT
Times cited: 28
Principles of nanoparticle design for overcoming biological barriers to drug delivery. Nature biotechnology. 2015 Review GET IT
Times cited: 2390
Retinal synaptic regeneration via microfluidic guiding channels. Scientific reports. 2015 Academic Article GET IT
Times cited: 11
Multistage vector (MSV) therapeutics. Journal of controlled release : official journal of the Controlled Release Society. 2015 Academic Article GET IT
Times cited: 43
Porous silicon microparticle potentiates anti-tumor immunity by enhancing cross-presentation and inducing type I interferon response. Cell reports. 2015 Academic Article GET IT
Times cited: 49
Circulating peptidome to indicate the tumor-resident proteolysis. Scientific reports. 2015 Academic Article GET IT
Times cited: 8
Mild hyperthermia enhances transport of liposomal gemcitabine and improves in vivo therapeutic response. Advanced healthcare materials. 2015 Academic Article GET IT
Times cited: 39
Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia. Blood. 2015 Academic Article GET IT
Times cited: 18
Porous silicon microparticles for delivery of siRNA therapeutics. Journal of visualized experiments : JoVE. 2015 Academic Article GET IT
Times cited: 31
Recent Advances in Discovering the Role of CCL5 in Metastatic Breast Cancer. Mini reviews in medicinal chemistry. 2015 Review GET IT
Times cited: 32
Safety of Nanoparticles in Medicine. Current drug targets. 2015 Review GET IT
Times cited: 149
Safety of nanoparticles in medicine. Current Drug Targets. 2015 Article
Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy. Journal of controlled release : official journal of the Controlled Release Society. 2014 Academic Article GET IT
Times cited: 82
Sublingual injection of microparticles containing glycolipid ligands for NKT cells and subunit vaccines induces antibody responses in oral cavity. Carbohydrate research. 2014 Academic Article GET IT
Times cited: 2
Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer. Physical biology. 2014 Academic Article GET IT
Times cited: 24
Human equilibrative nucleoside transporter-1 knockdown tunes cellular mechanics through epithelial-mesenchymal transition in pancreatic cancer cells. PloS one. 2014 Academic Article GET IT
Times cited: 11
The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia. Haematologica. 2014 Academic Article GET IT
Times cited: 17
Geometrical confinement of Gd(DOTA) molecules within mesoporous silicon nanoconstructs for MR imaging of cancer. Cancer letters. 2014 Review GET IT
Times cited: 25
Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 57
Bone marrow endothelium-targeted therapeutics for metastatic breast cancer. Journal of controlled release : official journal of the Controlled Release Society. 2014 Academic Article GET IT
Times cited: 41
Multifunctional gold nanorods for siRNA gene silencing and photothermal therapy. Advanced healthcare materials. 2014 Academic Article GET IT
Times cited: 76
Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells. Journal of microencapsulation. 2014 Academic Article GET IT
Times cited: 48
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. Nature. 2014 Academic Article GET IT
Times cited: 412
Transport properties of pancreatic cancer describe gemcitabine delivery and response. The Journal of clinical investigation. 2014 Academic Article GET IT
Times cited: 113
The nano-plasma interface: Implications of the protein corona. Colloids and surfaces. B, Biointerfaces. 2014 Academic Article GET IT
Times cited: 108
Transient mild hyperthermia induces E-selectin mediated localization of mesoporous silicon vectors in solid tumors. PloS one. 2014 Academic Article GET IT
Times cited: 10
Cyclodextrin and polyethylenimine functionalized mesoporous silica nanoparticles for delivery of siRNA cancer therapeutics. Theranostics. 2014 Academic Article GET IT
Times cited: 127
Polyarginine induces an antitumor immune response through binding to toll-like receptor 4. Small (Weinheim an der Bergstrasse, Germany). 2013 Academic Article GET IT
Times cited: 15
An IKKα-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity. Cell reports. 2013 Academic Article GET IT
Times cited: 14
Tumor vascular permeabilization using localized mild hyperthermia to improve macromolecule transport. Nanomedicine : nanotechnology, biology, and medicine. 2013 Academic Article GET IT
Times cited: 36
Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane. FEBS letters. 2013 Academic Article GET IT
Times cited: 6
Shrinkage of pegylated and non-pegylated liposomes in serum. Colloids and surfaces. B, Biointerfaces. 2013 Academic Article GET IT
Times cited: 72
Circulating proteolytic products of carboxypeptidase N for early detection of breast cancer. Clinical chemistry. 2013 Academic Article GET IT
Times cited: 25
High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics. ACS nano. 2013 Academic Article GET IT
Times cited: 83
Polycation-functionalized nanoporous silicon particles for gene silencing on breast cancer cells. Biomaterials. 2013 Academic Article GET IT
Times cited: 41
Estrogen receptor α regulates ATM Expression through miRNAs in breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Academic Article GET IT
Times cited: 42
Mesoporous silica coating on carbon nanotubes: layer-by-layer method. Langmuir : the ACS journal of surfaces and colloids. 2013 Academic Article GET IT
Times cited: 9
Delivery of gene silencing agents for breast cancer therapy. Breast cancer research : BCR. 2013 Academic Article GET IT
Times cited: 21
Identification of an inhibitory mechanism of luteolin on the insulin-like growth factor-1 ligand-receptor interaction. Chembiochem : a European journal of chemical biology. 2013 Academic Article GET IT
Times cited: 2
Enhancing chemotherapy response with sustained EphA2 silencing using multistage vector delivery. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Academic Article GET IT
Times cited: 80
Multistage vectored siRNA targeting ataxia-telangiectasia mutated for breast cancer therapy. Small (Weinheim an der Bergstrasse, Germany). 2013 Academic Article GET IT
Times cited: 46
Serum peptidomic biomarkers for pulmonary metastatic melanoma identified by means of a nanopore-based assay. Cancer letters. 2012 Academic Article GET IT
Times cited: 15
Hesperetin: an inhibitor of the transforming growth factor-β (TGF-β) signaling pathway. European journal of medicinal chemistry. 2012 Academic Article GET IT
Times cited: 28
Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells. Cell biochemistry and function. 2012 Academic Article GET IT
Times cited: 55
Monitoring the progression of metastatic breast cancer on nanoporous silica chips. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. 2012 Academic Article GET IT
Times cited: 27
Nanovector delivery of siRNA for cancer therapy. Cancer gene therapy. 2012 Review GET IT
Times cited: 116
Cooperative, nanoparticle-enabled thermal therapy of breast cancer. Advanced healthcare materials. 2011 Academic Article GET IT
Times cited: 77
Integrated genomic analyses of ovarian carcinoma. Nature. 2011 Academic Article GET IT
Surface engineering on mesoporous silica chips for enriching low molecular weight phosphorylated proteins. Nanoscale. 2010 Academic Article GET IT
Times cited: 27
Nanochannel technology for constant delivery of chemotherapeutics: beyond metronomic administration. Pharmaceutical research. 2010 Academic Article GET IT
Times cited: 33
Common sites of retroviral integration in mouse hematopoietic tumors identified by high-throughput, single nucleotide polymorphism-based mapping and bacterial artificial chromosome hybridization. Journal of virology. 2003 Academic Article GET IT
Times cited: 12
New genes involved in cancer identified by retroviral tagging. Nature genetics. 2002 Academic Article GET IT
Times cited: 349
Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 17
Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia. The Journal of biological chemistry. 2001 Academic Article GET IT
Times cited: 56
Diffuse large-cell and "true" histiocytic lymphomas of mice. Current topics in microbiology and immunology. 2000 Conference Paper GET IT
Times cited: 1
Leukaemia disease genes: large-scale cloning and pathway predictions. Nature genetics. 1999 Academic Article GET IT
Times cited: 200
Regulation of phosphatidylglycerophosphate synthase levels in Saccharomyces cerevisiae. The Journal of biological chemistry. 1998 Academic Article GET IT
Times cited: 22
Isolation and characterization of temperature-sensitive cdsl mutants of Saccharomyces cerevisiae. FASEB Journal. 1997 Article
Regulation of phospholipid biosynthetic enzymes by the level of CDP-diacylglycerol synthase activity. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 33
Reduction of CDP-diacylglycerol synthase activity results in the excretion of inositol by Saccharomyces cerevisiae. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 20
The CDS1 gene encoding CDP-diacylglycerol synthase in Saccharomyces cerevisiae is essential for cell growth. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 107

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Background

education and training

Ph.D., University of Texas Health Sciences Center, Houston 1997
M.S., Zhejiang Medical University (China) 1988
B.M., Zhejiang Medical University (China) 1985

Contact

full name

Haifa Shen

VIVO Weill Cornell Medical College

Haifa Shen Assistant Professor of Cell and Developmental Biology

Publications

selected publications

Background

education and training

Contact

full name