selected publications
- Discovery of CD28-Targeted Small Molecule Inhibitors of T Cell Co-Stimulation Using Affinity Selection-Mass Spectrometry (AS-MS) and Ex Vivo Validation. Journal of medicinal chemistry. 2025 Academic Article GET IT
- TREM2 activation by first-in-class direct small molecule agonists: DEL screening, optimization, biophysical validation, and functional characterization. European journal of medicinal chemistry. 2025 Academic Article GET IT
- Discovery of small molecule CHI3L1 inhibitors by SPR-based high-throughput screening. Bioorganic & medicinal chemistry letters. 2025 Academic Article GET IT
- Surface Plasmon Resonance (SPR)-Based Workflow for High-Throughput Discovery of CD28-Targeted Small Molecules. ACS omega. 2025 Academic Article GET IT
- Affinity Selection-Mass spectrometry coupled with biophysical validation enables proof-of-concept discovery of CHI3L1 binders. Biochemical and biophysical research communications. 2025 Academic Article GET IT
- Design and validation of the first-in-class PROTACs for targeted degradation of the immune checkpoint LAG-3. Bioorganic & medicinal chemistry letters. 2025 Academic Article GET IT
- c-KIT Small Molecule Inhibitors as a Therapeutic Strategy for Melanoma: Clinical Insights, SAR, and Future Directions. Archiv der Pharmazie. 2025 Review GET IT
- Discovery of a first-in-class SLIT2 binder disrupting the SLIT2/ROBO1 axis via DNA-encoded library (DEL) screening. RSC medicinal chemistry. 2025 Academic Article GET IT