Wang, Honggang

Publications

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selected publications

Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome. Nature communications. 2024 Academic Article GET IT
Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism. 2024 GET IT
Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022 Academic Article GET IT
Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors. JCI insight. 2021 Academic Article GET IT
Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations. Genetics in medicine : official journal of the American College of Medical Genetics. 2021 Academic Article GET IT
The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction. The Journal of clinical investigation. 2018 Academic Article GET IT
Times cited: 60
Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells. Cell stem cell. 2016 Academic Article GET IT
Times cited: 166
Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. Nature communications. 2014 Academic Article GET IT
Times cited: 86
Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 Academic Article GET IT
Times cited: 17
The auxiliary subunit KChIP2 is an essential regulator of homeostatic excitability. The Journal of biological chemistry. 2013 Academic Article GET IT
Times cited: 20
Rem2-targeted shRNAs reduce frequency of miniature excitatory postsynaptic currents without altering voltage-gated Ca²⁺ currents. PloS one. 2011 Academic Article GET IT
Times cited: 11
Accessory subunit KChIP2 modulates the cardiac L-type calcium current. Circulation research. 2009 Academic Article GET IT
Times cited: 70
Ca2+/CaM controls Ca2+-dependent inactivation of NMDA receptors by dimerizing the NR1 C termini. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Academic Article GET IT
Times cited: 27
Ca2+/calmodulin regulates trafficking of Ca(V)1.2 Ca2+ channels in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007 Academic Article GET IT
Times cited: 55
Presynaptic and postsynaptic roles of NO, cGK, and RhoA in long-lasting potentiation and aggregation of synaptic proteins. Neuron. 2005 Academic Article GET IT
Times cited: 169
Glycosylation affects rat Kv1.1 potassium channel gating by a combined surface potential and cooperative subunit interaction mechanism. The Journal of physiology. 2003 Academic Article GET IT
Times cited: 74
Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation. Science (New York, N.Y.). 2001 Academic Article GET IT
Times cited: 144
[Effects of L-NNA on postsynaptically evoked potential of oculomotoneurons in cats]. Sheng li xue bao : [Acta physiologica Sinica]. 1999 Academic Article GET IT
Presinusoidal vessels predominantly contract in response to norepinephrine, histamine, and KCl in rabbit liver. Journal of applied physiology (Bethesda, Md. : 1985). 1999 Academic Article GET IT
Times cited: 13
Effect of ONO-5046, a specific neutrophil elastase inhibitor, on the phorbol myristate acetate-induced injury in isolated dog lung. Experimental lung research. 1999 Academic Article GET IT
Times cited: 17
Lecithinized superoxide dismutase attenuates phorbol myristate acetate-induced injury in isolated dog lung. European journal of pharmacology. 1998 Academic Article GET IT
Times cited: 11
The role of endogenous nitric oxide in the sympathetic and hemodynamic response to platelet activating factor-induced hypotension in anesthetized dogs. Shock (Augusta, Ga.). 1998 Academic Article GET IT
Times cited: 6
Endothelin-1 selectively contracts portal vein through both ETA and ETB receptors in isolated rabbit liver. The American journal of physiology. 1997 Academic Article GET IT
Times cited: 38
Role of circulating blood components and thromboxane in anaphylactic vasoconstriction in isolated canine lungs. Journal of applied physiology (Bethesda, Md. : 1985). 1997 Academic Article GET IT
Times cited: 9
Effect of platelet-activating factor on hepatic capillary pressure in isolated dog liver. Prostaglandins, leukotrienes, and essential fatty acids. 1997 Academic Article GET IT
Times cited: 13
Thromboxane A2 analogue contracts predominantly the hepatic veins in isolated canine liver. Prostaglandins. 1996 Academic Article GET IT
Times cited: 18
Hepatic capillary pressure is estimated using triple vascular occlusion method in isolated canine liver. The American journal of physiology. 1996 Academic Article GET IT
Times cited: 11
Changes in tissue blood flow and sympathetic activities to various organs during prolonged hemorrhagic hypotension in monkeys. Journal of the autonomic nervous system. 1996 Academic Article GET IT
Times cited: 3
Differential regional sympathetic responses to somatic stimulation in anesthetized dogs. Journal of the autonomic nervous system. 1996 Academic Article GET IT
Times cited: 3
Participation of nitric oxide in the sympathetic response to anaphylactic hypotension in anesthetized dogs. Neuroscience letters. 1996 Academic Article GET IT
Times cited: 10
The effects of sevoflurane, enflurane, and isoflurane on baroreceptor-sympathetic reflex in rabbits. Anesthesia and analgesia. 1996 Academic Article GET IT
Times cited: 46
No effects of large doses of catecholamines on vascular permeability in isolated blood-perfused dog lungs. Acta physiologica Scandinavica. 1995 Academic Article GET IT
Times cited: 6
Suppression of sympathetic nervous system is involved in hypotension and bradycardia during hemofiltration in anesthetized dogs. Canadian journal of physiology and pharmacology. 1995 Academic Article GET IT
Times cited: 1
Effects of thromboxane A2 analogue on vascular resistance distribution and permeability in isolated blood-perfused dog lungs. Lung. 1995 Academic Article GET IT
Times cited: 13

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Research

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Funding awarded

Dynamic changes of the Nav1.5 interactome and contributions to heart failure awarded by National Heart, Lung, & Blood Institute Co-Investigator 2021 - 2025

Molecular and circuit defects underlying different SCN2A mutations and ASDs awarded by National Institute of Mental Health Key Personnel 2019 - 2025

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Background

education and training

Ph.D., Shinshu University (Japan) 1998
M.S., Hebei Medical University (China) 1987
B.M., Hebei Medical University (China) 1984

Contact

full name

Honggang Wang

primary email

how2006@med.cornell.edu

VIVO Weill Cornell Medical College

Honggang Wang Assistant Professor of Physiology Research in Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email