Pakula, Hubert

Publications

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selected publications

Targeting cancer metabolism: Therapeutic potential of the fatty acid synthase (FASN) inhibitors. Critical reviews in oncology/hematology. 2025 Review GET IT
Deciphering the Tumor Microenvironment in Prostate Cancer: A Focus on the Stromal Component. Cancers. 2024 Review GET IT
Times cited: 4
Blocking lipid synthesis induces DNA damage in prostate cancer and increases cell death caused by PARP inhibition. Science signaling. 2024 Academic Article GET IT
Times cited: 11
Interplay of IGF1R and estrogen signaling regulates hematopoietic stem and progenitor cells. 2024 GET IT
Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity. Cancer research. 2024 Academic Article GET IT
Times cited: 10
Distinct mesenchymal cell states mediate prostate cancer progression. Nature communications. 2024 Academic Article GET IT
Times cited: 21
Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer. Science translational medicine. 2023 Academic Article GET IT
Times cited: 30
Distinct mesenchymal cell states mediate prostate cancer progression. 2023 GET IT
"Stromal cells in prostate cancer pathobiology: friends or foes?". British journal of cancer. 2022 Review GET IT
Times cited: 31
Circulating Cell-Free DNA in Renal Cell Carcinoma: The New Era of Precision Medicine. Cancers. 2022 Review GET IT
Times cited: 15
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. Nature communications. 2021 Academic Article GET IT
Times cited: 60
Genetic ablation of FASN attenuates the invasive potential of prostate cancer driven by Pten loss. The Journal of pathology. 2020 Academic Article GET IT
Times cited: 18
CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer. Cell reports. 2019 Academic Article GET IT
Times cited: 49
Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell reports. 2018 Academic Article GET IT
Times cited: 70
LONG-NONCODING RNAs in gastroesophageal cancers. Non-coding RNA research. 2018 Review GET IT
Times cited: 34
Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis. Molecular cell. 2018 Academic Article GET IT
Times cited: 82
Protocols for Studies on TMPRSS2/ERG in Prostate Cancer. Methods in molecular biology (Clifton, N.J.). 2018 Academic Article GET IT
Times cited: 1
A Tale of Two Signals: AR and WNT in Development and Tumorigenesis of Prostate and Mammary Gland. Cancers. 2017 Review GET IT
Times cited: 47
Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence. Cell reports. 2015 Academic Article GET IT
Times cited: 21
MDM2 promotes cell motility and invasiveness through a RING-finger independent mechanism. FEBS letters. 2010 Academic Article GET IT
Times cited: 21

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Research

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Funding awarded

missing activity Co-Investigator 2024 - 2027
Investigating cell-intrinsic and extrinsic interactions in prostate cancer at the single cell level ("Core A: Pathobiology") awarded by National Cancer Institute Co-Investigator 2022 - 2027

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Background

education and training

Ph.D., Humboldt University, Faculty of Medicine (Germany) 2015
M.Sc., Poznan University of Medical Sciences (Poland) 2007

Contact

full name

Hubert Pakula

primary email

hup4002@med.cornell.edu

VIVO Weill Cornell Medical College

Hubert Pakula Assistant Professor of Research in Pathology and Laboratory Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email