Spitz, Irving Manfred

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Three Giants in the Cradle of Reproductive Medicine; Reproduction Theories of the Seventeenth Century as Discerned by Pregnancy Portraiture in the Oeuvre of Jan Vermeer. Rambam Maimonides medical journal. 2016 Academic Article GET IT
Free alpha-subunit is the most sensitive marker of gonadotropin recovery after treatment of central precocious puberty with the histrelin implant. The Journal of clinical endocrinology and metabolism. 2010 Academic Article GET IT
Times cited: 11
Mifepristone: where do we come from and where are we going? Clinical development over a quarter of a century. Contraception. 2010 Information Resource GET IT
Times cited: 45
Relationships between FSH, inhibin B, anti-Mullerian hormone, and testosterone during long-term treatment with the GnRH-agonist histrelin in patients with prostate cancer. European journal of endocrinology. 2009 Academic Article GET IT
Times cited: 16
Clinical utility of progesterone receptor modulators and their effect on the endometrium. Current opinion in obstetrics & gynecology. 2009 Information Resource GET IT
Times cited: 104
Is sildenafil citrate associated with an amelioration of the symptomatology of androgen decline in the aging male?. The Journal of urology. 2007 Academic Article GET IT
Times cited: 12
Long-term administration of mifepristone (RU486): clinical tolerance during extended treatment of meningioma. Cancer investigation. 2006 Academic Article GET IT
Times cited: 127
Progesterone receptor antagonists. Current opinion in investigational drugs (London, England : 2000). 2006 Information Resource GET IT
Times cited: 27
Management of patients receiving long-term treatment with mifepristone. Fertility and sterility. 2005 Academic Article GET IT
Times cited: 48
The histrelin implant: a novel treatment for central precocious puberty. Pediatrics. 2005 Academic Article GET IT
Times cited: 48
Dynamic assays of inhibin B, anti-Mullerian hormone and estradiol following FSH stimulation and ovarian ultrasonography as predictors of IVF outcome. Human reproduction (Oxford, England). 2005 Academic Article GET IT
Times cited: 216
Vaginal ring delivering estradiol and progesterone: a possible alternative to relieve climacteric symptoms. The Israel Medical Association journal : IMAJ. 2005 Academic Article GET IT
Times cited: 4
Serum anti-Mullerian hormone levels during controlled ovarian hyperstimulation in women with polycystic ovaries with and without hyperandrogenism. Human reproduction (Oxford, England). 2005 Academic Article GET IT
Times cited: 137
Selective progesterone receptor modulators and progesterone antagonists: mechanisms of action and clinical applications. Human reproduction update. 2005 Information Resource GET IT
Times cited: 259
Mifepristone does not induce cervical softening in non-pregnant women. Human reproduction (Oxford, England). 2004 Academic Article GET IT
Times cited: 13
Progesterone antagonists and progesterone receptor modulators. Expert opinion on investigational drugs. 2003 Information Resource GET IT
Times cited: 20
Estradiol/progesterone-releasing vaginal rings for hormone replacement therapy in postmenopausal women. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 2003 Academic Article GET IT
Times cited: 15
Effects of levonorgestrel-releasing intra-uterine system on the expression of vascular endothelial growth factor and adrenomedullin in the endometrium in adenomyosis. Human reproduction (Oxford, England). 2003 Academic Article GET IT
Times cited: 30
Proven and potential clinical applications of mifpristone (RU486). Reviews in endocrine & metabolic disorders. 2002 Information Resource GET IT
Times cited: 2
Serum inhibin B levels measured early during FSH administration for IVF may be of value in predicting the number of oocytes to be retrieved in normal and low responders. Human reproduction (Oxford, England). 2002 Academic Article GET IT
Times cited: 25
Follistatin and activin A serum concentrations in obese and non-obese patients with polycystic ovary syndrome. Human reproduction (Oxford, England). 2001 Academic Article GET IT
Times cited: 67
Effective long-term androgen suppression in men with prostate cancer using a hydrogel implant with the GnRH agonist histrelin. Urology. 2001 Academic Article GET IT
Times cited: 27
Effects of the levonorgestrel-releasing intrauterine system on proliferation and apoptosis in the endometrium. Human reproduction (Oxford, England). 2001 Academic Article GET IT
Times cited: 85
Tandem CAG repeats of the androgen receptor gene and prostate cancer risk in black and white men. Endocrine. 2001 Academic Article GET IT
Times cited: 38
Medical termination of pregnancy. The New England journal of medicine. 2000 Information Resource GET IT
Times cited: 114
An implant releasing the gonadotropin hormone-releasing hormone agonist histrelin maintains medical castration for up to 30 months in metastatic prostate cancer. The Journal of urology. 2000 Academic Article GET IT
Times cited: 31
Use of various ultrasonographic criteria to evaluate the efficacy of mifepristone and misoprostol for medical abortion. American journal of obstetrics and gynecology. 1999 Academic Article GET IT
Times cited: 16
Long-acting gonadotropin-releasing hormone implant to maintain medical castration for two years in men with prostate cancer. The New England journal of medicine. 1999 Article GET IT
Times cited: 11
Early pregnancy termination with mifepristone and misoprostol in the United States. The New England journal of medicine. 1998 Academic Article GET IT
Times cited: 352
Alterations in the pituitary-thyroid and pituitary-adrenal axes--consequences of long-term mifepristone treatment. Metabolism: clinical and experimental. 1997 Academic Article GET IT
Times cited: 32
Medical abortion. Current therapy in endocrinology and metabolism. 1997 Information Resource GET IT
Times cited: 5
Mifepristone: clinical pharmacology. Clinical obstetrics and gynecology. 1996 Information Resource GET IT
Times cited: 22
Antiprogestins: mechanism of action and contraceptive potential. Annual review of pharmacology and toxicology. 1996 Information Resource GET IT
Times cited: 71
Effect of administration of a gonadotropin-releasing hormone (GnRH) antagonist (Nal-Glu) during the periovulatory period: the luteinizing hormone surge requires secretion of GnRH. The Journal of clinical endocrinology and metabolism. 1994 Academic Article GET IT
Times cited: 61
The combination of gonadotrophin-releasing hormone (GnRH) antagonist and pulsatile GnRH normalizes luteinizing hormone secretion in polycystic ovarian disease but fails to induce follicular maturation. Human reproduction (Oxford, England). 1993 Academic Article GET IT
Times cited: 16
Mifepristone (RU 486)--a modulator of progestin and glucocorticoid action. The New England journal of medicine. 1993 Information Resource GET IT
Times cited: 189
Response to intermittent RU486 in women. Fertility and sterility. 1993 Academic Article GET IT
Times cited: 44
The divergent effect of RU 486 on adrenal function in the dog is related to differences in its pharmacokinetics. Acta endocrinologica. 1993 Academic Article GET IT
Times cited: 10
Spontaneous luteinizing hormone surges can be reliably prevented by the timely administration of a gonadotrophin releasing hormone antagonist (Nal-Glu) during the late follicular phase. Human reproduction (Oxford, England). 1992 Academic Article GET IT
Times cited: 39
Suppression of corpus luteum function by the gonadotropin-releasing hormone antagonist Nal-Glu: effect of the dose and timing of human chorionic gonadotropin administration. Fertility and sterility. 1991 Academic Article GET IT
Times cited: 49
Treatment of unresectable meningiomas with the antiprogesterone agent mifepristone. Journal of neurosurgery. 1991 Academic Article GET IT
Times cited: 282
Antiprogestin treatment decreases midluteal luteinizing hormone pulse amplitude and primarily exerts a pituitary inhibition. American journal of obstetrics and gynecology. 1990 Academic Article GET IT
Times cited: 10
Gonadotropin-releasing hormone (GnRH) agonists and GnRH antagonists do not alter endogenous GnRH secretion in short-term castrated rams. Endocrinology. 1990 Academic Article GET IT
Times cited: 28
Changes in gonadotropin and alpha-subunit secretion after a single administration of gonadotropin-releasing hormone antagonist in adult males. Fertility and sterility. 1990 Academic Article GET IT
Times cited: 18
The differential effects of the indazole-carboxylic acid derivative, tolnidamine, on Sertoli cell protein secretion. Journal of andrology. 1989 Academic Article GET IT
Times cited: 8
Variable effects of RU 486 on endometrial maintenance in the luteal phase extended by exogenous hCG. Clinical endocrinology. 1989 Academic Article GET IT
Times cited: 10
Progesterone antagonists on the horizon. Clinical obstetrics and gynecology. 1989 Information Resource GET IT
Times cited: 1
Response to the antiprogestagen RU 486 (mifepristone) during early pregnancy and the menstrual cycle in women. Journal of reproduction and fertility. Supplement. 1989 Information Resource GET IT
Times cited: 7
Effects of the antiprogestin RU486 on progesterone-dependent uterine development and bioassay of progestational activity in estrogen-primed immature female dogs. Acta endocrinologica. 1988 Academic Article GET IT
Times cited: 6
Effects of the antiglucocorticoid RU 486 on adrenal function in dogs. The Journal of clinical endocrinology and metabolism. 1988 Academic Article GET IT
Times cited: 12
Effects of the antiprogesterone RU 486 in normal women. I. Single-dose administration in the midluteal phase. American journal of obstetrics and gynecology. 1987 Academic Article GET IT
Times cited: 54
Effects of the antiprogesterone RU 486 in normal women. II. Administration in the late follicular phase. American journal of obstetrics and gynecology. 1987 Academic Article GET IT
Times cited: 98
Late luteal phase administration of RU486 for three successive cycles does not disrupt bleeding patterns or ovulation. The Journal of clinical endocrinology and metabolism. 1987 Academic Article GET IT
Times cited: 31
High-molecular-weight serum thyrotropin revisited. The New England journal of medicine. 1987 Article GET IT
Times cited: 4
Termination of early gestation with the anti-progestin steroid RU 486: medium versus low dose. Contraception. 1987 Academic Article GET IT
Times cited: 40
Plasma concentrations and receptor binding of RU 486 and its metabolites in humans. Journal of steroid biochemistry. 1987 Academic Article GET IT
Times cited: 102
The progesterone antagonist RU 486. A potential new contraceptive agent. The New England journal of medicine. 1987 Academic Article GET IT
Times cited: 72
Pharmacokinetics and metabolism of RU 486. Journal of steroid biochemistry. 1987 Academic Article GET IT
Times cited: 87
Pregnancy termination with a high and medium dosage regimen of RU 486. Contraception. 1986 Academic Article GET IT
Times cited: 41
Antiprogestins: prospects for a once-a-month pill. Family planning perspectives. 1985 Academic Article GET IT
The effects of the indazole carboxylic acid derivative, tolnidamine, on testicular function: I. Early changes in androgen binding protein secretion in the rat. Journal of andrology. 1985 Academic Article GET IT
Times cited: 9
Growth and sexual development before and after sex steroid therapy in patients with thalassemia major. Archives of internal medicine. 1984 Academic Article GET IT
Times cited: 12
Hormonal profile after insulin-induced hypoglycemia in chronic calcific pancreatitis. Pancreatic, pituitary and adrenal responses. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1984 Academic Article GET IT
Times cited: 2
TSH secretion in thalassemia. Journal of endocrinological investigation. 1984 Academic Article GET IT
Times cited: 5
Effect of non aromatizable androgens on LHRH and TRH responses in primary testicular failure. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1984 Academic Article GET IT
The interrelationships between prolactin and thyrotrophin secretion following dopaminergic blockage in patients with mild hyperprolactinaemia without any demonstrable pituitary tumour. Clinical endocrinology. 1983 Academic Article GET IT
Times cited: 2
The dissociation of the exaggerated prolactin and thyrotropin responses in seminiferous tubule failure following the administration of a double-pulse of thyrotropin-releasing hormone. Journal of endocrinological investigation. 1983 Academic Article GET IT
The thyrotropin (TSH) profile in isolated gonadotropin deficiency: a model to evaluate the effect of sex steroids on TSH secretion. The Journal of clinical endocrinology and metabolism. 1983 Academic Article GET IT
Times cited: 22
The role of thyrotrophin releasing hormone in the diagnosis of isolated gonadotrophin deficiency. Journal of steroid biochemistry. 1983 Academic Article GET IT
Times cited: 1
Gonadotropin-prolactin interrelationship in the Hre/+ rat: a longitudinal study. Biology of reproduction. 1983 Academic Article GET IT
Times cited: 1
The prolactin response to thyrotropin-releasing hormone differentiates isolated gonadotropin deficiency from delayed puberty. The New England journal of medicine. 1983 Academic Article GET IT
Times cited: 47
Dopaminergic regulation of prolactin secretion in the hyperprolactinemic syndrome. Gynecologic and obstetric investigation. 1983 Academic Article GET IT
Times cited: 1
The decreased basal and stimulated prolactin levels in isolated gonadotrophin deficiency: a consequence of the low oestrogen state. Clinical endocrinology. 1982 Academic Article GET IT
Times cited: 19
Betazole-induced GIP secretion is not mediated by gastric HCl. Metabolism: clinical and experimental. 1982 Academic Article GET IT
Times cited: 14
Increased prolactin response to thyrotropin-releasing hormone in primary ovarian failure. Obstetrics and gynecology. 1982 Academic Article GET IT
Times cited: 3
Prolactin responsiveness to TRH and metoclopramide in thalassaemia. Clinical endocrinology. 1982 Academic Article GET IT
Times cited: 7
Clomiphene citrate does not modify the exaggerated thyrotrophin response to thyrotrophin-releasing hormone occurring in primary testicular failure. Clinical endocrinology. 1982 Academic Article GET IT
Times cited: 2
The effect of methionine enkephalin on prolactin and luteinizing hormone levels in intact and castrated rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1982 Academic Article GET IT
Times cited: 3
Dissociation between sleep-related and TRH-induced prolactin secretion in seminiferous tubule failure. Metabolism: clinical and experimental. 1982 Academic Article GET IT
Times cited: 1
Gonadotrophin, testosterone and prolactin interrelationships in cadmium-treated rats. The Journal of endocrinology. 1982 Academic Article GET IT
Times cited: 44
Effects of testosterone, dihydrotestosterone, and estradiol on the impaired prolactin response to metoclopramide in the castrated rat. Biology of reproduction. 1981 Academic Article GET IT
Times cited: 5
Prolactin response to metoclopramide in the castrated male rat. Biology of reproduction. 1981 Academic Article GET IT
Times cited: 1
Gonadal function in lepromatous leprosy. Leprosy review. 1981 Academic Article GET IT
Times cited: 13
The TSH response to TRH is exaggerated in primary testicular failure and normal in the male castrate. Acta endocrinologica. 1981 Academic Article GET IT
Times cited: 17
Prolactin response to metoclopramide and chlorpromazine in primary testicular failure and isolated gonadotrophin deficiency. Clinical endocrinology. 1981 Academic Article GET IT
Times cited: 7
Clomiphene attenuates the exaggerated prolactin response to thyrotropin-releasing hormone and metoclopramide occurring in primary testicular failure. The Journal of clinical endocrinology and metabolism. 1981 Academic Article GET IT
Times cited: 11
The prolactin response to thyrotrophin-releasing hormone is intact in the human male castrate. Acta endocrinologica. 1981 Academic Article GET IT
Times cited: 4
Serum prolactin levels in spermatic, renal, and cubital veins during spermatic vein ligation. International journal of fertility. 1981 Academic Article GET IT
The exaggerated prolactin response to thyrotropin-releasing hormone and metoclopramide in 1,2-dibromo-3-chloropropane-induced azoospermia. The Journal of clinical endocrinology and metabolism. 1981 Academic Article GET IT
Times cited: 10
Acid-induced gastric inhibitory polypeptide secretion in man. The Journal of clinical endocrinology and metabolism. 1980 Academic Article GET IT
Times cited: 12
Exaggerated prolactin response to thyrotropin-releasing hormone and metoclopramide in primary testicular failure. Fertility and sterility. 1980 Academic Article GET IT
Times cited: 16
The hypothalamic-pituitary axis in diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1980 Academic Article GET IT
Times cited: 13
Diminished prolactin reserve in acromegaly. Metabolism: clinical and experimental. 1980 Academic Article GET IT
Times cited: 10
Hypothalamic-pituitary function in the Bardet-Biedl syndrome. Israel journal of medical sciences. 1980 Academic Article GET IT
Times cited: 10
[Dissociation of responses of prolactin and TSH to repeated pulses of thyrotropin releasing hormone]. Harefuah. 1980 Academic Article GET IT
Dissociation of pituitary glycoprotein response to releasing hormones in chronic renal failure. Acta endocrinologica. 1980 Academic Article GET IT
Times cited: 17
Dissociation of prolactin response to thyrotropin-releasing hormone and metoclopramide in chronic renal failure. The Journal of clinical endocrinology and metabolism. 1979 Academic Article GET IT
Times cited: 14
Failure of metoclopramide to influence LH, FSH and TSH secretion or their responses to releasing hormones. Acta endocrinologica. 1979 Academic Article GET IT
Times cited: 11
Hypothalamic-pituitary function in Cushing's disease. Journal of endocrinological investigation. 1979 Academic Article GET IT
Times cited: 3
Prolactin nonresponsiveness to arginine in diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1979 Academic Article GET IT
Times cited: 4
Impaired prolactin response to thyrotropin-releasing hormone in isolated gonadotropin deficiency and exaggerated response in primary testicular failure. The Journal of clinical endocrinology and metabolism. 1979 Academic Article GET IT
Times cited: 39
Atropine suppression of basal and metoclopramide-induced human pancreatic polypeptide secretion in man. Metabolism: clinical and experimental. 1979 Academic Article GET IT
Times cited: 12
The prolactin response to repeated intravenous stimuli. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1979 Academic Article GET IT
Hyperprolactinaemia and hypogonadism in men: response to exogenous gonadotrophins. Clinical endocrinology. 1979 Academic Article GET IT
Times cited: 19
Failure of bromocriptine to suppress prolactin in majeptil-induced hyperprolactinemia. Acta Europaea fertilitatis. 1978 Academic Article GET IT
Times cited: 1
Gonadotrophin, thyrotrophin and prolactin reserve in beta thalassaemia. Clinical endocrinology. 1978 Academic Article GET IT
Times cited: 38
[Increased blood parathormone (PTH) level in a case of hyperprolactinemia]. La Nouvelle presse medicale. 1977 Article GET IT
Times cited: 2
Dissociation of prolactin responsiveness to TRH and chlorpromazine in women with isolated gonadotropin deficiency. The Journal of clinical endocrinology and metabolism. 1977 Academic Article GET IT
Times cited: 23
Hormonal response to exogenous luteinizing hormone-releasing hormone and thyrotropin-releasing hormone in pregnancy and puerperium. Israel journal of medical sciences. 1977 Academic Article GET IT
Times cited: 3
Isolated hypogonadotropic hypogonadism: induction of ovulation with exogenous gonadotropins. Fertility and sterility. 1977 Academic Article GET IT
Times cited: 5
Isolated gonadotropin deficiency and related disorders. Israel journal of medical sciences. 1975 Information Resource GET IT
Times cited: 10
Elevtion of serum testosterone in ovarian hyperstimulation syndrome. The Journal of clinical endocrinology and metabolism. 1975 Academic Article GET IT
Times cited: 13
Isolated deficiency of follicle-stimulating hormone: Further studies. The Journal of clinical endocrinology and metabolism. 1975 Academic Article GET IT
Times cited: 8
Alpha subunit of glycoprotein hormone: presence in peripheral serum after LHRH. European journal of clinical investigation. 1975 Academic Article GET IT
Times cited: 12
Isolated gonadotropin deficiency. A heterogenous syndrome. The New England journal of medicine. 1974 Academic Article GET IT
Times cited: 51
Metabolic features of Johannesburg Bantu with myocardial infarction. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1973 Academic Article GET IT
Times cited: 3
Binding of human LH to particulate fraction of rat testis: disparity in LH:IRP equipotency ratios in immuno-and ligand assay. Metabolism: clinical and experimental. 1973 Academic Article GET IT
Times cited: 7
Thyroid function tests in the first year of life. Israel journal of medical sciences. 1973 Academic Article GET IT
Times cited: 1
Effects of single and multiple pulses of arginine on insulin release in man. The Journal of clinical endocrinology and metabolism. 1973 Academic Article GET IT
Times cited: 12
Development of anti-human FSH antibody in a patient with isolated FSH deficiency. The Journal of clinical endocrinology and metabolism. 1973 Academic Article GET IT
Times cited: 20
Heterogeneity of gonadotropin response to LHRH in hypogonadotropic hypogonadism. The Journal of clinical endocrinology and metabolism. 1973 Academic Article GET IT
Times cited: 69
Isolated deficiency of follicle-stimulating hormone. Clinical and laboratory features. The New England journal of medicine. 1972 Academic Article GET IT
Times cited: 61
Agnogenic and stimulus-initiated growth hormone release in man. A reappraisal and a multiple pool model of hormonal release. The Johns Hopkins medical journal. 1972 Academic Article GET IT
Times cited: 3
Biologic activity of proinsulin in an isolated fat-cell system. Israel journal of medical sciences. 1972 Academic Article GET IT
Times cited: 1
Single and multiple arginine pulses in man: effect on insulin release. Israel journal of medical sciences. 1972 Academic Article GET IT
Urine excretion of insulin and growth hormone in subjects with renal failure. Acta endocrinologica. 1971 Academic Article GET IT
Times cited: 5
Metabolic and hormonal effects of xylitol in man. Zeitschrift fur Ernahrungswissenschaft. Journal of nutritional sciences. Supplementa. 1971 Academic Article GET IT
Times cited: 2
The response of growth hormone to xylitol administration in man. The American journal of the medical sciences. 1970 Academic Article GET IT
Times cited: 1
Urine insulin in renal disease. The Journal of laboratory and clinical medicine. 1970 Academic Article GET IT
Times cited: 11
The blood sugar and serum insulin response to intravenous glucagon in chronic renal failure. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1970 Academic Article GET IT
Times cited: 2
Carbohydrate metabolism in renal disease. The Quarterly journal of medicine. 1970 Academic Article GET IT
Times cited: 48
The effect of dialysis on the carbohydrate intolerance of chronic renal failure. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1970 Academic Article GET IT
Times cited: 10
Metabolism of xylitol in healthy subjects and patients with renal disease. Metabolism: clinical and experimental. 1970 Academic Article GET IT
Times cited: 28
Serum-growth hormone and glucose intolerance in renal failure. Lancet (London, England). 1968 Academic Article GET IT
Times cited: 57
Studies on patients receiving alpha-methyldopa: observations on red cell life span. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1968 Academic Article GET IT
Role of the kidney in insulin metabolism and excretion. Diabetes. 1968 Information Resource GET IT
Times cited: 81
Auto-immune haemolytic anaemia associated with alpha-methyldopa therapy--a case report. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1967 Academic Article GET IT

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Background

education and training

M.D., University of Witwatersrand Faculty of Health Sciences (South Africa) 1971
M.B.,B.Ch., University of Witwatersrand Faculty of Health Sciences (South Africa) 1962

Contact

full name

Irving Manfred Spitz

VIVO Weill Cornell Medical College

Irving Manfred Spitz Adjunct Professor of Medicine

Publications

selected publications

Background

education and training

Contact

full name

Phone

Publications

selected publications

Background

education and training

Contact

full name