Bromberg, Jacqueline Francoise

selected publications

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020 Academic Article GET IT
Times cited: 778
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis. Nature cell biology. 2019 Academic Article GET IT
Times cited: 280
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of extracellular vesicles. 2018 Academic Article GET IT
Times cited: 7463
Association of PI3K Pathway Mutations with Early Positron-Emission Tomography/CT Imaging Response after Radioembolization for Breast Cancer Liver Metastases: Results of a Single-Center Retrospective Pilot Study. Journal of vascular and interventional radiology : JVIR. 2018 Academic Article GET IT
Times cited: 12
Phase II Study of Paclitaxel and Dasatinib in Metastatic Breast Cancer. Clinical breast cancer. 2018 Academic Article GET IT
Times cited: 39
Abscopal Effect after Radioembolization for Metastatic Breast Cancer in the Setting of Immunotherapy. Journal of vascular and interventional radiology : JVIR. 2018 Article GET IT
Times cited: 8
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation. Nature cell biology. 2018 Academic Article GET IT
Times cited: 1193
In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of ¹⁸F-(2S,4R)-4-Fluoroglutamine. Radiology. 2018 Academic Article GET IT
Times cited: 84
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming. Genes & development. 2017 Academic Article GET IT
Times cited: 41
p-STAT3 in luminal breast cancer: Integrated RNA-protein pooled analysis and results from the BIG 2-98 phase III trial. International journal of oncology. 2017 Academic Article GET IT
Times cited: 15
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 538
A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 31
Pre-metastatic niches: organ-specific homes for metastases. Nature reviews. Cancer. 2017 Information Resource GET IT
Times cited: 624
Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles. Cancer research. 2017 Academic Article GET IT
Times cited: 118
Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 23
Hepatocellular adenoma among adult survivors of childhood and young adult cancer. Pediatric blood & cancer. 2016 Academic Article GET IT
Times cited: 7
JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors. Science signaling. 2016 Academic Article GET IT
Times cited: 57
Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer. Nature communications. 2016 Academic Article GET IT
Times cited: 144
Tumour exosome integrins determine organotropic metastasis. Nature. 2015 Academic Article GET IT
Times cited: 3763
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver. Nature cell biology. 2015 Academic Article GET IT
Times cited: 2065
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation. Nature communications. 2015 Academic Article GET IT
Times cited: 88
JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response. Cancer discovery. 2015 Academic Article GET IT
Times cited: 244
The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study. Journal of the National Cancer Institute. 2014 Academic Article GET IT
Times cited: 115
Linking signaling pathways to transcriptional programs in breast cancer. Genome research. 2014 Academic Article GET IT
Times cited: 49
RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch. Oncogene. 2014 Academic Article GET IT
Times cited: 35
Role of MAPK in oncolytic herpes viral therapy in triple-negative breast cancer. Cancer gene therapy. 2014 Academic Article GET IT
Times cited: 19
Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 72
Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell research. 2014 Article GET IT
Times cited: 1319
IL-6 regulates adipose deposition and homeostasis in lymphedema. American journal of physiology. Heart and circulatory physiology. 2014 Academic Article GET IT
Times cited: 77
The IL-6 feed-forward loop: a driver of tumorigenesis. Seminars in immunology. 2014 Information Resource GET IT
Times cited: 56
Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier. Cancer research. 2013 Academic Article GET IT
Times cited: 29
The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis. Neoplasia (New York, N.Y.). 2013 Academic Article GET IT
Th2 differentiation is necessary for soft tissue fibrosis and lymphatic dysfunction resulting from lymphedema. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 Academic Article GET IT
Times cited: 175
AZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell lines. PloS one. 2012 Academic Article GET IT
Times cited: 19
STAT3 negatively regulates thyroid tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 114
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature medicine. 2012 Academic Article GET IT
Times cited: 3008
Targeting the interleukin-6/Jak/stat pathway in human malignancies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2012 Information Resource GET IT
Times cited: 443
Stat3 mediates expression of autotaxin in breast cancer. PloS one. 2011 Academic Article GET IT
Times cited: 67
Antitumorigenic potential of STAT3 alternative splicing modulation. Proceedings of the National Academy of Sciences of the United States of America. 2011 Academic Article GET IT
Times cited: 140
Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer. Clinical breast cancer. 2011 Academic Article GET IT
Times cited: 116
A phase I study of dasatinib and weekly paclitaxel for metastatic breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology. 2011 Academic Article GET IT
Times cited: 51
Environment, inflammation, and cancer. Current opinion in genetics & development. 2010 Information Resource GET IT
Times cited: 52
Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation. Breast cancer research : BCR. 2010 Academic Article GET IT
Times cited: 70
Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis. Blood. 2010 Academic Article GET IT
Times cited: 69
A phase II trial of erlotinib in combination with bevacizumab in patients with metastatic breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008 Academic Article GET IT
Times cited: 110
Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008 Academic Article GET IT
Times cited: 54
Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Academic Article GET IT
Times cited: 140
Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas. The Journal of clinical investigation. 2007 Academic Article GET IT
Times cited: 586
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6. Molecular and cellular biology. 2007 Academic Article GET IT
Times cited: 138
Increased dose density is feasible: a pilot study of adjuvant epirubicin and cyclophosphamide followed by paclitaxel, at 10- or 11-day intervals with filgrastim support in women with breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007 Academic Article GET IT
Times cited: 9
Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer. Breast cancer research : BCR. 2007 Academic Article GET IT
Times cited: 209
Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells. Cancer research. 2006 Academic Article GET IT
Times cited: 127
Touched and moved by STAT3. Science's STKE : signal transduction knowledge environment. 2006 Information Resource GET IT
Times cited: 68
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer research. 2006 Academic Article GET IT
Times cited: 195
Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 226
The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3. Proceedings of the National Academy of Sciences of the United States of America. 2003 Academic Article GET IT
Times cited: 153
IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. Molecular biology of the cell. 2003 Academic Article GET IT
Times cited: 137
Human immunodeficiency virus type 1 Nef mediates activation of STAT3 in immature dendritic cells. AIDS research and human retroviruses. 2002 Academic Article GET IT
Times cited: 23
IL-6 rescues the hyporesponsiveness of c-Rel deficient B cells independent of Bcl-xL, Mcl-1, and Bcl-2. Cellular immunology. 2002 Academic Article GET IT
Times cited: 27
Stat proteins and oncogenesis. The Journal of clinical investigation. 2002 Information Resource GET IT
Times cited: 785
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene. 2002 Academic Article GET IT
Times cited: 948
Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1. Proceedings of the National Academy of Sciences of the United States of America. 2001 Academic Article GET IT
Times cited: 233
Activation of STAT proteins and growth control. BioEssays : news and reviews in molecular, cellular and developmental biology. 2001 Information Resource GET IT
Times cited: 238
The role of STATs in transcriptional control and their impact on cellular function. Oncogene. 2000 Information Resource GET IT
Times cited: 1000
Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development. Breast cancer research : BCR. 2000 Information Resource GET IT
Times cited: 104
Stat3 as an oncogene. Cell. 1999 Academic Article GET IT
Times cited: 2383
A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation. Molecular and cellular biology. 1999 Academic Article GET IT
Times cited: 109
Epidermal growth factor-induced growth inhibition requires Stat1 activation. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1998 Academic Article GET IT
Times cited: 103
Stat3 activation is required for cellular transformation by v-src. Molecular and cellular biology. 1998 Academic Article GET IT
Times cited: 577
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 452
Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4. Nature. 1992 Academic Article GET IT
Times cited: 164

VIVO Weill Cornell Medical College

Jacqueline Francoise Bromberg Associate Professor of Medicine

Publications

selected publications

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Publications

selected publications

Contact

full name