Ferreira, Jacob

Publications

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selected publications

Addition to "Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation". 2024 GET IT
Carbonic Anhydrase Inhibitor Modulation of Intraocular Pressure Is Independent of Soluble Adenylyl Cyclase. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 2023 Academic Article GET IT
Times cited: 2
Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. Journal of chemical information and modeling. 2023 Academic Article GET IT
Times cited: 4
Corrigendum: Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential. 2023 GET IT
On-demand male contraception via acute inhibition of soluble adenylyl cyclase. Nature communications. 2023 Academic Article GET IT
Times cited: 50
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates. Journal of medicinal chemistry. 2022 Academic Article GET IT
Times cited: 12
Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential. Frontiers in physiology. 2022 Academic Article GET IT
Times cited: 6
Strategies to safely target widely expressed soluble adenylyl cyclase for contraception. Frontiers in pharmacology. 2022 Academic Article GET IT
Times cited: 14
Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization. Molecular human reproduction. 2021 Academic Article GET IT
Times cited: 38
Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10). ACS medicinal chemistry letters. 2021 Academic Article GET IT
Times cited: 18
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates. Cell chemical biology. 2016 Academic Article GET IT
Times cited: 25
Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations. Journal of medicinal chemistry. 2016 Academic Article GET IT
Times cited: 20

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Background

education and training

Ph.D., Weill Cornell Graduate School of Medical Sciences 24
Pharm.D., University of Connecticut 2018
B.S., University of Connecticut 2016

Contact

full name

Jacob Ferreira

primary email

jaf4002@med.cornell.edu

VIVO Weill Cornell Medical College

Jacob Ferreira Postdoctoral Associate in Pharmacology

Publications

selected publications

Background

education and training

Contact

full name

primary email