selected publications
- Addition to "Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation". 2024 GET IT
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Carbonic Anhydrase Inhibitor Modulation of Intraocular Pressure Is Independent of Soluble Adenylyl Cyclase.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
2023
Academic Article
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Times cited: 2 -
Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation.
Journal of chemical information and modeling.
2023
Academic Article
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Times cited: 4 - Corrigendum: Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential. 2023 GET IT
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On-demand male contraception via acute inhibition of soluble adenylyl cyclase.
Nature communications.
2023
Academic Article
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Times cited: 49 -
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.
Journal of medicinal chemistry.
2022
Academic Article
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Times cited: 11 -
Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential.
Frontiers in physiology.
2022
Academic Article
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Times cited: 6 -
Strategies to safely target widely expressed soluble adenylyl cyclase for contraception.
Frontiers in pharmacology.
2022
Academic Article
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Times cited: 14 -
Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization.
Molecular human reproduction.
2021
Academic Article
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Times cited: 37 -
Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).
ACS medicinal chemistry letters.
2021
Academic Article
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Times cited: 18 -
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
Cell chemical biology.
2016
Academic Article
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Times cited: 25 -
Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations.
Journal of medicinal chemistry.
2016
Academic Article
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Times cited: 20