Flory, James

Publications

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selected publications

The Large Language Model GPT-4 Compared to Endocrinologist Responses on Initial Choice of Antidiabetic Medication under Conditions of Clinical Uncertainty. Diabetes care. 2024 Academic Article GET IT
Individualized clinical decisions within standard-of-care pragmatic clinical trials: Implications for consent. Clinical trials (London, England). 2024 Academic Article GET IT
Taking clinical decisions seriously in standard-of-care pragmatic clinical trials. Clinical trials (London, England). 2024 Academic Article GET IT
Role of primary care in opioid prescribing for older head and neck cancer survivors. Cancer. 2024 Academic Article GET IT
Application of a data continuity prediction algorithm to an electronic health record-based pharmacoepidemiology study. Journal of evaluation in clinical practice. 2024 Academic Article GET IT
Validation of an international classification of disease, tenth revision, clinical modification (ICD-10-CM) algorithm in identifying severe hypoglycaemia events for real-world studies. Diabetes, obesity & metabolism. 2024 Academic Article GET IT
Sodium-glucose cotransporter-2 inhibitors for hypergycemia in phosphoinositide 3-kinase pathway inhibition. Breast cancer research and treatment. 2023 Academic Article GET IT
Decision architecture randomisation: extremely efficient clinical trials that preserve clinician and patient choice?. BMJ evidence-based medicine. 2023 Academic Article GET IT
Group sequential testing under instrumented difference-in-differences approach. Statistics in medicine. 2023 Academic Article GET IT
Exocrine Pancreatic Insufficiency Induced by Immune Checkpoint Inhibitors. The oncologist. 2023 Academic Article GET IT
Sodium-glucose cotransporter 2 inhibitor-induced postoperative euglycaemic diabetic ketoacidosis after pancreatectomy. The British journal of surgery. 2023 Academic Article GET IT
Preoperative glucose in surgical oncology patient is not associated with postoperative outcomes after adjustment for frailty. Journal of surgical oncology. 2023 Academic Article GET IT
Instrumented difference-in-differences. Biometrics. 2022 Academic Article GET IT
Climate Change and Ambient Temperature Extremes: Association With Serious Hypoglycemia, Diabetic Ketoacidosis, and Sudden Cardiac Arrest/Ventricular Arrhythmia in People With Type 2 Diabetes. Diabetes care. 2022 Letter GET IT
Times cited: 9
Prescriber Uncertainty as Opportunity to Improve Care of Type 2 Diabetes with Chronic Kidney Disease: Mixed Methods Study. Journal of general internal medicine. 2022 Academic Article GET IT
Rejoinder to "Instrumented difference-in-differences". Biometrics. 2022 Academic Article GET IT
Times cited: 1
Impact of the Affordable Care Act's Physician Payments Sunshine Act on branded statin prescribing. Health services research. 2022 Academic Article GET IT
Comparative Safety of Sodium-Glucose Cotransporter 2 Inhibitors Versus Dipeptidyl Peptidase 4 Inhibitors and Sulfonylureas on the Risk of Diabetic Ketoacidosis. Diabetes care. 2022 Academic Article GET IT
Baseline haemoglobin A1c and the risk of COVID-19 hospitalization among patients with diabetes in the INSIGHT Clinical Research Network. Diabetic medicine : a journal of the British Diabetic Association. 2022 Academic Article GET IT
Characterization, management, and risk factors of hyperglycemia during PI3K or AKT inhibitor treatment. Cancer medicine. 2022 Academic Article GET IT
Impact of a Provider Tele-mentoring Learning Model on the Care of Medicaid-enrolled Patients With Diabetes. Medical care. 2022 Academic Article GET IT
Chronic Medication Nonadherence and Potentially Preventable Healthcare Utilization and Spending Among Medicare Patients. Journal of general internal medicine. 2022 Academic Article GET IT
Impact of New York State's Health Home program on access to care among patients with diabetes. BMJ open diabetes research & care. 2021 Academic Article GET IT
Angiotensin-Converting Enzyme Inhibitors Used Concomitantly with Insulin Secretagogues and the Risk of Serious Hypoglycemia. Clinical pharmacology and therapeutics. 2021 Academic Article GET IT
Comparative Safety of Dipeptidyl Peptidase-4 Inhibitors and Sudden Cardiac Arrest and Ventricular Arrhythmia: Population-Based Cohort Studies. Clinical pharmacology and therapeutics. 2021 Academic Article GET IT
Clinical subphenotypes in COVID-19: derivation, validation, prediction, temporal patterns, and interaction with social determinants of health. NPJ digital medicine. 2021 Academic Article GET IT
Times cited: 16
Spotlight commentary: A role for real-world evidence to inform the clinical care of patients with diabetes mellitus. British journal of clinical pharmacology. 2021 Academic Article GET IT
Compared to commercially insured patients, Medicare advantage patients adopt newer diabetes drugs more slowly and adhere to them less. Endocrinology, diabetes & metabolism. 2021 Academic Article GET IT
Rates of Metformin Use in Stage 3b Chronic Kidney Disease Rose After FDA Label Change. Journal of general internal medicine. 2021 Academic Article GET IT
Functional clustering methods for longitudinal data with application to electronic health records. Statistical methods in medical research. 2020 Academic Article GET IT
Response to Comment on Flory et al. Reports of Lactic Acidosis Attributed to Metformin, 2015-2018. Diabetes Care 2020;43:244-246. Diabetes care. 2020 Article GET IT
Times cited: 2
Trial of restarting and tolerating metformin (TreatMet). Diabetes, obesity & metabolism. 2020 Academic Article GET IT
Times cited: 1
Risk of sudden cardiac arrest and ventricular arrhythmia with sulfonylureas: An experience with conceptual replication in two independent populations. Scientific reports. 2020 Academic Article GET IT
Times cited: 11
"Not Alone Anymore": The Experiences of Adults With Diabetes in New York's Medicaid Health Home Program. Medical care. 2020 Academic Article GET IT
Characterization of on-target adverse events caused by TRK inhibitor therapy. Annals of oncology : official journal of the European Society for Medical Oncology. 2020 Academic Article GET IT
Times cited: 47
Effect of Cost and Formulation on Persistence and Adherence to Initial Metformin Therapy for Type 2 Diabetes. Diabetes care. 2020 Article GET IT
The risk of sudden cardiac arrest and ventricular arrhythmia with rosiglitazone versus pioglitazone: real-world evidence on thiazolidinedione safety. Cardiovascular diabetology. 2020 Academic Article GET IT
Times cited: 15
Twelve-year trends in pharmacologic treatment of type 2 diabetes among patients with heart failure in the United States. Diabetes, obesity & metabolism. 2020 Academic Article GET IT
Times cited: 2
Hospitalization as an Opportunity to Optimize Glycemic Control in Oncology Patients. Current diabetes reports. 2019 Information Resource GET IT
Times cited: 1
Reports of Lactic Acidosis Attributed to Metformin, 2015-2018. Diabetes care. 2019 Academic Article GET IT
Times cited: 22
Metformin for Type 2 Diabetes-Reply. JAMA. 2019 Article GET IT
Overcoming barriers to the use of metformin: patient and provider perspectives. Patient preference and adherence. 2019 Academic Article GET IT
Times cited: 9
Metformin in 2019. JAMA. 2019 Information Resource GET IT
Times cited: 311
Feature Selection in Predictive Modeling: A Systematic Study on Drug Response Heterogeneity for Type II Diabetic Patients. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. 2019 Academic Article GET IT
Ethical Acceptability of Postrandomization Consent in Pragmatic Clinical Trials. JAMA network open. 2018 Academic Article GET IT
Times cited: 3
Review of Metformin Use for Type 2 Diabetes Prevention. American journal of preventive medicine. 2018 Information Resource GET IT
Times cited: 52
Identifying prevalence and risk factors for metformin non-persistence: a retrospective cohort study using an electronic health record. BMJ open. 2018 Academic Article GET IT
Times cited: 17
Diagnosis-based cohort augmentation using laboratory results data: The case of chronic kidney disease. Pharmacoepidemiology and drug safety. 2018 Academic Article GET IT
Times cited: 1
From Sour Grapes to Low-Hanging Fruit: A Case Study Demonstrating a Practical Strategy for Natural Language Processing Portability. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. 2018 Academic Article GET IT
Comparative Safety of Sulfonylureas and the Risk of Sudden Cardiac Arrest and Ventricular Arrhythmia. Diabetes care. 2018 Academic Article GET IT
Times cited: 25
Rejoinder. Clinical trials (London, England). 2018 Article GET IT
Ethics and practice of Trials within Cohorts: An emerging pragmatic trial design. Clinical trials (London, England). 2017 Academic Article GET IT
Times cited: 40
Comparative risk of serious hypoglycemia with oral antidiabetic monotherapy: A retrospective cohort study. Pharmacoepidemiology and drug safety. 2017 Academic Article GET IT
Times cited: 45
Instrumental Variable Methods for Continuous Outcomes That Accommodate Nonignorable Missing Baseline Values. American journal of epidemiology. 2017 Academic Article GET IT
Times cited: 2
Agreement and validity of electronic health record prescribing data relative to pharmacy claims data: A validation study from a US electronic health record database. Pharmacoepidemiology and drug safety. 2017 Academic Article GET IT
Times cited: 11
Pro- and Antiarrhythmic Actions of Sulfonylureas: Mechanistic and Clinical Evidence. Trends in endocrinology and metabolism: TEM. 2017 Information Resource GET IT
Times cited: 36
Comparative adherence to diabetes drugs: An analysis of electronic health records and claims data. Diabetes, obesity & metabolism. 2017 Academic Article GET IT
Times cited: 9
A tutorial on the use of instrumental variables in pharmacoepidemiology. Pharmacoepidemiology and drug safety. 2017 Information Resource GET IT
Times cited: 33
Missing laboratory results data in electronic health databases: implications for monitoring diabetes risk. Journal of comparative effectiveness research. 2016 Academic Article GET IT
Times cited: 7
Novel Anti-glycemic Drugs and Reduction of Cardiovascular Risk in Diabetes: Expectations Realized, Promises Unmet. Current atherosclerosis reports. 2016 Information Resource GET IT
Times cited: 6
Citizen Petition to the US Food and Drug Administration to Change Prescribing Guidelines: The Metformin Experience. Circulation. 2016 Academic Article GET IT
Times cited: 29
Diabetes Management in Cancer Patients. Oncology (Williston Park, N.Y.). 2016 Academic Article GET IT
Methods for using clinical laboratory test results as baseline confounders in multi-site observational database studies when missing data are expected. Pharmacoepidemiology and drug safety. 2016 Academic Article GET IT
Times cited: 6
Selection Bias When Using Instrumental Variable Methods to Compare Two Treatments But More Than Two Treatments Are Available. The international journal of biostatistics. 2016 Academic Article GET IT
Times cited: 8
Comparative risk of severe hypoglycemia among concomitant users of thiazolidinedione antidiabetic agents and antihyperlipidemics. Diabetes research and clinical practice. 2016 Academic Article GET IT
Times cited: 5
A Sensitivity Analysis to Assess Bias Due to Selecting Subjects Based on Treatment Received. Epidemiology (Cambridge, Mass.). 2016 Article GET IT
Times cited: 4
Severe hypoglycemia in users of sulfonylurea antidiabetic agents and antihyperlipidemics. Clinical pharmacology and therapeutics. 2016 Academic Article GET IT
Times cited: 22
Stage 2 hypertension: predictors of failure to achieve blood pressure control and the impact of adding one additional antihypertensive class. Pharmacoepidemiology and drug safety. 2015 Academic Article GET IT
Times cited: 5
Methadone Use and the Risk of Hypoglycemia for Inpatients With Cancer Pain. Journal of pain and symptom management. 2015 Academic Article GET IT
Times cited: 24
Proton pump inhibitors do not impair the effectiveness of metformin in patients with diabetes. British journal of clinical pharmacology. 2015 Academic Article GET IT
Times cited: 11
What Is the Right Way to Respect Patient Perspectives?. The American journal of bioethics : AJOB. 2015 Article GET IT
Observational and clinical trial findings on the comparative effectiveness of diabetes drugs showed agreement. Journal of clinical epidemiology. 2014 Academic Article GET IT
Times cited: 5
Basal Insulin Use in the Non-Critical Care Setting: Is Fasting Hypoglycemia Inevitable or Preventable?. Journal of diabetes science and technology. 2014 Article GET IT
Comparative effectiveness of oral diabetes drug combinations in reducing glycosylated hemoglobin. Journal of comparative effectiveness research. 2014 Academic Article GET IT
Times cited: 17
Charge variability for acute appendicitis: is the problem overstated?. Archives of internal medicine. 2012 Article GET IT
Simulation study of instrumental variable approaches with an application to a study of the antidiabetic effect of bezafibrate. Pharmacoepidemiology and drug safety. 2012 Academic Article GET IT
Times cited: 5
Observational cohort study of the safety of digoxin use in women with heart failure. BMJ open. 2012 Academic Article GET IT
Times cited: 9
High prevalence of aquagenic wrinkling of the palms in patients with cystic fibrosis and association with measurable increases in transepidermal water loss. Pediatric dermatology. 2012 Academic Article GET IT
Times cited: 27
Clinical importance of the drug interaction between statins and CYP3A4 inhibitors: a retrospective cohort study in The Health Improvement Network. Pharmacoepidemiology and drug safety. 2012 Academic Article GET IT
Times cited: 41
Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nature genetics. 2011 Academic Article GET IT
Times cited: 286
Duplication of the SLIT3 locus on 5q35.1 predisposes to major depressive disorder. PloS one. 2010 Academic Article GET IT
Times cited: 56
Strong synaptic transmission impact by copy number variations in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 172
Variants of DENND1B associated with asthma in children. The New England journal of medicine. 2009 Academic Article GET IT
Times cited: 249
Common variants at five new loci associated with early-onset inflammatory bowel disease. Nature genetics. 2009 Academic Article GET IT
Times cited: 420
17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry. The Journal of allergy and clinical immunology. 2009 Article GET IT
Times cited: 64
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature. 2009 Academic Article GET IT
Times cited: 1104
Antidiabetic action of bezafibrate in a large observational database. Diabetes care. 2009 Academic Article GET IT
Times cited: 34
Socioeconomic risk factors for bacteraemic pneumococcal pneumonia in adults. Epidemiology and infection. 2008 Academic Article GET IT
Times cited: 55
Interventions to improve research participants' understanding in informed consent for research: a systematic review. JAMA. 2004 Information Resource GET IT
Times cited: 743
Place of death: U.S. trends since 1980. Health affairs (Project Hope). 2004 Academic Article GET IT
Times cited: 169
Global health and the scientific research agenda. Philosophy & public affairs. 2004 Academic Article GET IT
Times cited: 59
Surfing the Web for innovation. Managed care interface. 1997 Academic Article GET IT
Health care commerce on the net: the revolution begins. Medical interface. 1997 Academic Article GET IT
Health care systems reach out over the Internet: Part II. Medical interface. 1997 Academic Article GET IT
Health care systems reach out over the Internet: Part I. Medical interface. 1997 Academic Article GET IT
Internet strategies being implemented by pharmaceutical companies. Medical interface. 1997 Academic Article GET IT
Secrets and tips for weaving a Web of success. Part 1. Medical interface. 1997 Academic Article GET IT
The Internet revolution: transforming health care delivery. Medical interface. 1997 Academic Article GET IT
Lasso the power of the Internet. InfoCare : information strategies for healthcare networks. 1997 Academic Article GET IT
The health care executive's involvement in cost containment. Osteopathic hospital leadership. 1985 Academic Article GET IT
A look at the future of the health care system. Radiology management. 1985 Academic Article GET IT
Wanted: CEOs and trustees with a business perspective. Trustee : the journal for hospital governing boards. 1984 Academic Article GET IT

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Background

education and training

M.D., University of Pennsylvania School of Medicine 2009
M.S.C.E., University of Pennsylvania School of Medicine 2009
B.A., Columbia University 2002

Contact

full name

James Flory

primary email

jaf9052@med.cornell.edu

VIVO Weill Cornell Medical College

James Flory Associate Professor of Population Health Sciences

Publications

selected publications

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email