Barchas, Jack D

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Neurotransmission-related gene expression in the frontal pole is altered in subjects with bipolar disorder and schizophrenia. Translational psychiatry. 2023 Review GET IT
Times cited: 7
Large Common Mitochondrial DNA Deletions Are Associated with a Mitochondrial SNP T14798C Near the 3' Breakpoints. Complex psychiatry. 2022 Academic Article GET IT
Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder. Translational psychiatry. 2022 Academic Article GET IT
Identification of potential blood biomarkers associated with suicide in major depressive disorder. Translational psychiatry. 2022 Academic Article GET IT
Rare coding variants in ten genes confer substantial risk for schizophrenia. Nature. 2022 Academic Article GET IT
Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA_A receptors. Translational psychiatry. 2019 Academic Article GET IT
Times cited: 10
Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders. Nucleic acids research. 2019 Academic Article GET IT
Times cited: 29
Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature genetics. 2019 Review GET IT
Times cited: 1119
Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis. PloS one. 2018 Academic Article GET IT
Times cited: 56
Connective Tissue Growth Factor Is a Novel Prodepressant. Biological psychiatry. 2018 Academic Article GET IT
Times cited: 19
Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature communications. 2018 Academic Article GET IT
Times cited: 119
Quantitative validation of immunofluorescence and lectin staining using reduced CLARITY acrylamide formulations. Brain structure & function. 2017 Academic Article GET IT
Times cited: 8
Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence. Molecular neuropsychiatry. 2017 Academic Article GET IT
Post-mortem molecular profiling of three psychiatric disorders. Genome medicine. 2017 Academic Article GET IT
Times cited: 169
Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder. 2016 GET IT
Times cited: 3
The microRNA network is altered in anterior cingulate cortex of patients with unipolar and bipolar depression. Journal of psychiatric research. 2016 Academic Article GET IT
Times cited: 74
Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders. Microarrays (Basel, Switzerland). 2016 Academic Article GET IT
Times cited: 2
Evidence for alterations of the glial syncytial function in major depressive disorder. Journal of psychiatric research. 2015 Academic Article GET IT
Times cited: 101
Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder. Translational psychiatry. 2015 Academic Article GET IT
Times cited: 86
Fibroblast growth factor 9 is a novel modulator of negative affect. Proceedings of the National Academy of Sciences of the United States of America. 2015 Academic Article GET IT
Times cited: 49
Mitochondrial mutations in subjects with psychiatric disorders. PloS one. 2015 Academic Article GET IT
Times cited: 45
Introduction for affective disorders and traumatic brain injury: Qatar clinical neuroscience conference. Annals of the New York Academy of Sciences. 2015 Article GET IT
Perspectives on depression--past, present, future(a). Annals of the New York Academy of Sciences. 2015 Review GET IT
Times cited: 5
Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder. Molecular psychiatry. 2014 Review GET IT
Times cited: 163
Altered choroid plexus gene expression in major depressive disorder. Frontiers in human neuroscience. 2014 Academic Article GET IT
Times cited: 48
G protein-linked signaling pathways in bipolar and major depressive disorders. Frontiers in genetics. 2013 Academic Article GET IT
Times cited: 70
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature genetics. 2013 Academic Article GET IT
Times cited: 1864
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nature genetics. 2011 Academic Article GET IT
Times cited: 1125
Sociophysiology 25 years ago: early perspectives of an emerging discipline now part of social neuroscience. Annals of the New York Academy of Sciences. 2011 Academic Article GET IT
Times cited: 2
Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population. Schizophrenia research. 2011 Academic Article GET IT
Times cited: 18
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proceedings of the National Academy of Sciences of the United States of America. 2009 Review GET IT
Times cited: 252
Aaron Lerner: perspectives and lessons learned from the melatonin days. The Journal of investigative dermatology. 2007 Academic Article GET IT
Times cited: 1
General psychiatry. JAMA. 1998 Article GET IT
Times cited: 1
The imperative for research on severe mental disorders. The journal of the California Alliance for the Mentally Ill. 1994 Academic Article GET IT
Times cited: 1
Tandem mass spectrometry for the trace determination of tryptolines in crude brain extracts. Analytical chemistry. 1984 Academic Article GET IT
Times cited: 40
Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proceedings of the National Academy of Sciences of the United States of America. 1983 Academic Article GET IT
Times cited: 99
Dissociation of long-term analgesia and the shuttle box escape deficit caused by inescapable shock. Journal of comparative and physiological psychology. 1982 Academic Article GET IT
Times cited: 23
Studies of beta-endorphin in psychiatric patients. Annals of the New York Academy of Sciences. 1982 Academic Article GET IT
Times cited: 8
Neural differentiation in the OTT-6050 mouse teratoma: enzymatic and immunofluorescence characterization of a tumor fraction showing melanogenesis in neuroepithelial cells. Virchows Archiv. A, Pathological anatomy and histology. 1981 Academic Article GET IT
Times cited: 17
Opiate antagonists and long-term analgesic reaction induced by inescapable shock in rats. Journal of comparative and physiological psychology. 1980 Academic Article GET IT
Times cited: 113
N5,10-methylenetetrahydrofolate reductase activity in autopsied brain parts of chronic schizophrenics and controls and in vitro tryptoline formation. Biological psychiatry. 1978 Academic Article GET IT
Times cited: 7
Serotonin involvement in pituitary-adrenal function. Annals of the New York Academy of Sciences. 1977 Academic Article GET IT
Times cited: 34
A possible role for the dorsal periventricular catecholamine bundle in stimulation produced analgesia: a behavioral and histochemical study. Brain research. 1977 Academic Article GET IT
Times cited: 14

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Background

education and training

M.D., Yale University School of Medicine 1961
B.A., Pomona College 1956

Contact

full name

Jack D Barchas

primary email

jbarchas@med.cornell.edu

VIVO Weill Cornell Medical College

Jack D Barchas Professor Emeritus of Psychiatry

Publications

selected publications

Background

education and training

Contact

full name

primary email