de Graaff, Jurgen

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selected publications

Perspectives of children, parents and health care providers on outcomes following anesthesia for surgery:: An international mixed methods stakeholder engagement study from the Pediatric Perioperative Outcomes Group. Anesthesiology. 2026 Academic Article GET IT
HERNIIA-II trial (Hernia Endoscopic oR opeN repair In chIldren Analysis): a protocol of a multicentre randomised controlled trial to study the (cost-)effectiveness of laparoscopic hernia repair compared to open hernia repair in children 0-16 years. BMJ open. 2025 Academic Article GET IT
Intra-operative physiologic interventions associated with postoperative neurological complications in neonates and infants: A secondary analysis of the NECTARINE cohort. European journal of anaesthesiology. 2025 Academic Article GET IT
Intraoperative Hypotension in Children: How to Define Too Low?. Paediatric anaesthesia. 2025 Editorial Article GET IT
Mortality and Surgery-Related Complications in Very Low and Extreme Low Birth Weight Infants Treated for Esophageal Atresia: A Multi-Center Cohort Study. Journal of pediatric surgery. 2025 Academic Article GET IT
Times cited: 1
Core outcome sets for pediatric perioperative research: An international stakeholder engagement exercise and consensus report from the Pediatric Perioperative Outcomes Group. Anesthesiology. 2025 Academic Article GET IT
Quantitative electroencephalogram and machine learning to predict expired sevoflurane concentration in infants. Journal of clinical monitoring and computing. 2025 Academic Article GET IT
Short-term Outcomes in Infants after General Anesthesia with Low-dose Sevoflurane/Dexmedetomidine/Remifentanil versus Standard-dose Sevoflurane (the TREX Trial). Anesthesiology. 2024 Academic Article GET IT
Times cited: 5
Neurodevelopmental Outcomes after Multiple General Anesthetic Exposures before 5 Years of Age: A Cohort Study. Anesthesiology. 2024 Academic Article GET IT
Times cited: 12
International multi-institutional external validation of preoperative risk scores for 30-day in-hospital mortality in paediatric patients. British journal of anaesthesia. 2024 Academic Article GET IT
Times cited: 1
Brain health: A concern for anaesthesiologists and intensivists. European journal of anaesthesiology and intensive care. 2024 Review GET IT
Times cited: 4
Pediatric anesthesia in Europe: Variations within uniformity. Paediatric anaesthesia. 2024 Review GET IT
Times cited: 7
Automatic Max-Likelihood Envelope Detection Algorithm for Quantitative High-Frame-Rate Ultrasound for Neonatal Brain Monitoring. Ultrasound in medicine & biology. 2023 Academic Article GET IT
A comparison of ultrafast and conventional spectral Doppler ultrasound to measure cerebral blood flow velocity during inguinal hernia repair in infants. Journal of clinical anesthesia. 2023 Academic Article GET IT
Times cited: 4
Perioperative anaesthetic management and short-term outcome of neonatal repair of oesophageal atresia with or without tracheo-oesophageal fistula in Europe: A sub-analysis of the neonate and children audit of anaesthesia practice in Europe (NECTARINE) prospective multicenter observational study. European journal of anaesthesiology. 2023 Academic Article GET IT
Times cited: 6
The eXpectations of Parents regarding Anesthesiology Study (XPAS) from a parental perspective: a two-phase observational cross-sectional cohort study. Paediatric anaesthesia. 2023 Academic Article GET IT
Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery. Journal of cardiovascular translational research. 2023 Academic Article GET IT
Times cited: 4
Epidemiology and outcomes of inguinal surgery with or without regional anaesthesia in neonates and small infants: A subanalysis of the NECTARINE database. European journal of anaesthesiology. 2023 Letter GET IT
Times cited: 3
Incidence and between-center heterogeneity of anesthesia-related complications in pediatric populations documented in administrative data: A retrospective study. Paediatric anaesthesia. 2023 Academic Article GET IT
Ephedrine to treat intraoperative hypotension in infants: what is the target?. British journal of anaesthesia. 2023 Editorial Article GET IT
Times cited: 2
Age-dependent changes in arterial blood pressure in neonates during the first week of life: reference values and development of a model. British journal of anaesthesia. 2023 Academic Article GET IT
Times cited: 15
Perioperative Mortality in Pediatric Patients: A Systematic Review of Risk Assessment Tools for Use in the Preoperative Setting. Anesthesiology. 2022 Academic Article GET IT
Times cited: 13
Needle-free pharmacological sedation techniques in paediatric patients for imaging procedures: a systematic review and meta-analysis. British journal of anaesthesia. 2022 Review GET IT
Times cited: 24
Neonates undergoing pyloric stenosis repair are at increased risk of difficult airway management: secondary analysis of the NEonate and Children audiT of Anaesthesia pRactice IN Europe. British journal of anaesthesia. 2022 Academic Article GET IT
Times cited: 5
Isoelectric Electroencephalography in Infants and Toddlers during Anesthesia for Surgery: An International Observational Study. Anesthesiology. 2022 Academic Article GET IT
Times cited: 30
Neonatal Pain, Opioid, and Anesthetic Exposure; What Remains in the Human Brain After the Wheels of Time?. Frontiers in pediatrics. 2022 Academic Article GET IT
Times cited: 2
Serious Adverse Events after a Single Shot of Intrathecal Morphine: A Case Series and Systematic Review. Pain research & management. 2022 Academic Article GET IT
Times cited: 22
Cognitive Outcomes in Children With Conditions Affecting the Small Intestine: A Systematic Review and Meta-analysis. Journal of pediatric gastroenterology and nutrition. 2022 Review GET IT
Times cited: 9
Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe: A prospective European multicentre observational study. European journal of anaesthesiology. 2022 Academic Article GET IT
Times cited: 26
Cerebral Oxygenation and Activity During Surgical Repair of Neonates With Congenital Diaphragmatic Hernia: A Center Comparison Analysis. Frontiers in pediatrics. 2021 Academic Article GET IT
Times cited: 3
Neurocardiovascular coupling in congenital diaphragmatic hernia patients undergoing different types of surgical treatment. European journal of anaesthesiology. 2021 Academic Article GET IT
Times cited: 2
Identifying studies on medication error in anaesthesiology. Comment on Br J Anaesth 2021; 127: 458-69. British journal of anaesthesia. 2021 Letter GET IT
Long-term neurodevelopment in children born with esophageal atresia: a systematic review. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 2021 Academic Article GET IT
Times cited: 17
Predicting hypotension during pediatric anesthesia: Can we move beyond a definition that is in the eye of the beholder?. Paediatric anaesthesia. 2021 Editorial Article GET IT
Times cited: 1
Contralateral surgical exploration during inguinal hernia repair in infants (HERNIIA trial): study protocol for a multi-centre, randomised controlled trial. Trials. 2021 Academic Article GET IT
Times cited: 4
Primary repair of esophageal atresia is followed by multiple diagnostic and surgical procedures. Journal of pediatric surgery. 2021 Academic Article GET IT
Times cited: 6
Associations of perioperative characteristics with motor function in preschool children born with esophageal atresia. Paediatric anaesthesia. 2021 Academic Article GET IT
Times cited: 7
Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE). British journal of anaesthesia. 2021 Academic Article GET IT
Times cited: 140
Feasibility of Doppler Ultrasound for Cortical Cerebral Blood Flow Velocity Monitoring During Major Non-cardiac Surgery of Newborns. Frontiers in pediatrics. 2021 Academic Article GET IT
Times cited: 5
Anesthesiological approach to the floppy child. Minerva anestesiologica. 2021 Review GET IT
Times cited: 3
Best practice & research clinical anesthesiology: Safety and quality in perioperative anesthesia care. Update on safety in pediatric anesthesia. Best practice & research. Clinical anaesthesiology. 2020 Review GET IT
Times cited: 24
Off-label use of dexmedetomidine in paediatric anaesthesiology: an international survey of 791 (paediatric) anaesthesiologists. European journal of clinical pharmacology. 2020 Academic Article GET IT
Times cited: 26
Mitochondrial Oxygen Monitoring During Surgical Repair of Congenital Diaphragmatic Hernia or Esophageal Atresia: A Feasibility Study. Frontiers in pediatrics. 2020 Academic Article GET IT
Times cited: 5
Artifacts annotations in anesthesia blood pressure data by man and machine. Journal of clinical monitoring and computing. 2020 Academic Article GET IT
Times cited: 10
Towards integrative neuromonitoring of the surgical newborn: A systematic review. European journal of anaesthesiology. 2020 Academic Article GET IT
Times cited: 12
A retrospective cohort study of adverse event assessment during anesthesia-related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers. Paediatric anaesthesia. 2020 Academic Article GET IT
Times cited: 2
A systematic review of outcomes reported inpediatric perioperative research: A report from the Pediatric Perioperative Outcomes Group. Paediatric anaesthesia. 2020 Academic Article GET IT
Times cited: 33
Artifact Processing Methods Influence on Intraoperative Hypotension Quantification and Outcome Effect Estimates. Anesthesiology. 2020 Academic Article GET IT
Times cited: 13
Effect of hyperextension of the neck (rose position) on cerebral blood oxygenation in patients who underwent cleft palate reconstructive surgery: prospective cohort study using near-infrared spectroscopy. Clinical oral investigations. 2020 Academic Article GET IT
Times cited: 6
Patient and anesthesia characteristics of children with low pre-incision blood pressure: A retrospective observational study. Acta anaesthesiologica Scandinavica. 2019 Academic Article GET IT
Times cited: 2
The effect of intrathecal bupivacaine/morphine on quality of recovery in robot-assisted radical prostatectomy: a randomised controlled trial. Anaesthesia. 2019 Academic Article GET IT
Times cited: 48
Perioperative management of esophageal atresia/tracheo-esophageal fistula: An analysis of data of 101 consecutive patients. Paediatric anaesthesia. 2019 Academic Article GET IT
Times cited: 23
Statistical Analysis Plan for "An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery". Paediatric anaesthesia. 2019 Academic Article GET IT
Times cited: 7
Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. Lancet (London, England). 2019 Academic Article GET IT
Times cited: 586
A systematic review and narrative synthesis on the histological and neurobehavioral long-term effects of dexmedetomidine. Paediatric anaesthesia. 2019 Review GET IT
Times cited: 19
An open label pilot study of a dexmedetomidine-remifentanil-caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study. Paediatric anaesthesia. 2019 Academic Article GET IT
Times cited: 41
What we can learn from Big Data about factors influencing perioperative outcome. Current opinion in anaesthesiology. 2018 Review GET IT
Times cited: 13
Enrollment challenges in multicenter, international studies: The example of the GAS trial. Paediatric anaesthesia. 2018 Academic Article GET IT
Times cited: 6
Anesthesia and the developing brain: A way forward for laboratory and clinical research. Paediatric anaesthesia. 2018 Review GET IT
Times cited: 94
Navigating Between Scylla and Charybdis; Sevoflurane for Difficult Sedation at the PICU. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2018 Editorial Article GET IT
Times cited: 4
Intraoperative blood pressure levels in young and anaesthetised children: are we getting any closer to the truth?. Current opinion in anaesthesiology. 2018 Review GET IT
Times cited: 23
Pediatric perioperative outcomes group: Defining core outcomes for pediatric anesthesia and perioperative medicine. Paediatric anaesthesia. 2018 Editorial Article GET IT
Times cited: 21
The incidence of postoperative respiratory complications: A retrospective analysis of cuffed vs uncuffed tracheal tubes in children 0-7 years of age. Paediatric anaesthesia. 2018 Academic Article GET IT
Times cited: 31
Incidence of Artifacts and Deviating Values in Research Data Obtained from an Anesthesia Information Management System in Children. Anesthesiology. 2018 Academic Article GET IT
Times cited: 26
Surgical practice and outcome in 711 neonates and infants undergoing hernia repair in a large multicenter RCT: Secondary results from the GAS Study. Journal of pediatric surgery. 2018 Academic Article GET IT
Times cited: 17
An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal Anesthesia. Anesthesiology. 2018 Academic Article GET IT
Times cited: 67
Differences in Blood Pressure in Infants After General Anesthesia Compared to Awake Regional Anesthesia (GAS Study-A Prospective Randomized Trial). Anesthesia and analgesia. 2017 Academic Article GET IT
Times cited: 88
How big data shape paediatric anaesthesia. British journal of anaesthesia. 2017 Editorial Article GET IT
Times cited: 7
A survey of the dose of inhalational agents used to maintain anaesthesia in infants. European journal of anaesthesiology. 2017 Academic Article GET IT
Times cited: 4
Current thinking regarding potential neurotoxicity of general anesthesia in infants. Current opinion in urology. 2017 Review GET IT
Times cited: 16
Long-term Effects of Early Exposure to Stress, Pain, Opioids and Anaesthetics on Pain Sensitivity and Neurocognition. Current pharmaceutical design. 2017 Review GET IT
Times cited: 27
Minimally Invasive Strip Craniectomy Simplifies Anesthesia Practice in Patients With Isolated Sagittal Synostosis. The Journal of craniofacial surgery. 2016 Academic Article GET IT
Times cited: 13
Reference Values for Noninvasive Blood Pressure in Children during Anesthesia: A Multicentered Retrospective Observational Cohort Study. Anesthesiology. 2016 Academic Article GET IT
Times cited: 118
Outcomes in the trial registry should match those in the protocol - Authors' reply. Lancet (London, England). 2016 Letter GET IT
The GAS trial - Authors' reply. Lancet (London, England). 2016 Letter GET IT
Times cited: 3
Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial. Lancet (London, England). 2015 Academic Article GET IT
Times cited: 796
Neonatal brain oxygenation during thoracoscopic correction of esophageal atresia. Surgical endoscopy. 2015 Academic Article GET IT
Times cited: 48
Perioperative hospital mortality at a tertiary paediatric institution. British journal of anaesthesia. 2015 Academic Article GET IT
Times cited: 46
Reporting critical incidents in a tertiary hospital: a historical cohort study of 110,310 procedures. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2015 Academic Article GET IT
Times cited: 20
Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial. Anesthesiology. 2015 Academic Article GET IT
Times cited: 186
Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair: Data from the General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes. Anesthesiology. 2015 Academic Article GET IT
Times cited: 50
Cuffed or uncuffed endotracheal tubes in pediatric anesthesia: a survey of current practice in the United Kingdom and The Netherlands. Paediatric anaesthesia. 2015 Letter GET IT
Times cited: 17
Anesthesia and the developing brain: a way forward for clinical research. Paediatric anaesthesia. 2015 Review GET IT
Times cited: 45
Anesthesia-related critical incidents in the perioperative period in children; a proposal for an anesthesia-related reporting system for critical incidents in children. Paediatric anaesthesia. 2015 Academic Article GET IT
Times cited: 66
Evaluating NIR vascular imaging to support intravenous cannulation in awake children difficult to cannulate; a randomized clinical trial. Paediatric anaesthesia. 2014 Academic Article GET IT
Times cited: 24
Postoperative pain during the first week after adenoidectomy and guillotine adenotonsillectomy in children. Paediatric anaesthesia. 2014 Academic Article GET IT
Times cited: 30
Perioperative complications in patients diagnosed with mucopolysaccharidosis and the impact of enzyme replacement therapy followed by hematopoietic stem cell transplantation at early age. Paediatric anaesthesia. 2014 Academic Article GET IT
Times cited: 25
Response to letter regarding article, "myocardial injury after noncardiac surgery and its association with short-term mortality". Circulation. 2014 Comment GET IT
Times cited: 1
Anesthetic implications of infants with mandibular hypoplasia treated with mandibular distraction osteogenesis. Paediatric anaesthesia. 2014 Letter GET IT
Times cited: 1
Near-infrared light to aid peripheral intravenous cannulation in children: a cluster randomised clinical trial of three devices. Anaesthesia. 2013 Academic Article GET IT
Times cited: 72
Incidence of intraoperative hypoxemia in children in relation to age. Anesthesia and analgesia. 2013 Academic Article GET IT
Times cited: 88
Myocardial injury after noncardiac surgery and its association with short-term mortality. Circulation. 2013 Academic Article GET IT
Times cited: 278
The effectiveness of a near-infrared vascular imaging device to support intravenous cannulation in children with dark skin color: a cluster randomized clinical trial. Anesthesia and analgesia. 2013 Academic Article GET IT
Times cited: 42
General anesthesia as a possible GABAergic modulator affects visual processing in children. Frontiers in cellular neuroscience. 2013 Academic Article GET IT
Times cited: 3
[Is anaesthesia detrimental to brain development?]. Nederlands tijdschrift voor geneeskunde. 2013 Academic Article GET IT
Times cited: 2
Near-infrared imaging in intravenous cannulation in children: a cluster randomized clinical trial. Pediatrics. 2012 Academic Article GET IT
Times cited: 39
Preoperative testing in noncardiac surgery patients: a survey amongst European anaesthesiologists. European journal of anaesthesiology. 2012 Academic Article GET IT
Times cited: 14
The use of near-infrared light for safe and effective visualization of subsurface blood vessels to facilitate blood withdrawal in children. Medical engineering & physics. 2012 Academic Article GET IT
Times cited: 63
Artifacts in research data obtained from an anesthesia information and management system. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2012 Academic Article GET IT
Times cited: 33
Difficult arterial cannulation in children: is a near-infrared vascular imaging system the answer?. British journal of anaesthesia. 2012 Academic Article GET IT
Times cited: 25
Factors influencing blood loss and allogeneic blood transfusion practice in craniosynostosis surgery. Paediatric anaesthesia. 2011 Academic Article GET IT
Times cited: 44
Predictive factors for difficult intravenous cannulation in pediatric patients at a tertiary pediatric hospital. Paediatric anaesthesia. 2011 Academic Article GET IT
Times cited: 67
Visualizing veins with near-infrared light to facilitate blood withdrawal in children. Clinical pediatrics. 2011 Academic Article GET IT
Times cited: 36
Medication discontinuity errors in the perioperative period. Acta anaesthesiologica Scandinavica. 2010 Academic Article GET IT
Times cited: 13
Early transection of a central venous catheter in a sedated ICU patient. 2006 GET IT
Times cited: 8
The diagnostic randomized clinical trial is the best solution for management issues in critical limb ischemia. Journal of clinical epidemiology. 2004 Academic Article GET IT
Times cited: 9
Influence of peripheral arterial disease on capillary pressure in the foot. Journal of vascular surgery. 2003 Academic Article GET IT
Times cited: 19
Evaluation of toe pressure and transcutaneous oxygen measurements in management of chronic critical leg ischemia: a diagnostic randomized clinical trial. Journal of vascular surgery. 2003 Academic Article GET IT
Times cited: 73
Postural changes in capillary pressure in the hallux of healthy volunteers. Journal of applied physiology (Bethesda, Md. : 1985). 2003 Academic Article GET IT
Times cited: 16
Interobserver variation in duplex scanning of infrainguinal arterial bypass grafts. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 2003 Academic Article GET IT
Times cited: 7
The impact of peripheral and coronary artery disease on health-related quality of life. Annals of vascular surgery. 2002 Academic Article GET IT
Times cited: 37
The feasibility and reliability of capillary blood pressure measurements in the fingernail fold. Microvascular research. 2002 Academic Article GET IT
Times cited: 14
Impaired vascular function in women with pre-eclampsia observed with orthogonal polarisation spectral imaging. BJOG : an international journal of obstetrics and gynaecology. 2001 Academic Article GET IT
Times cited: 18
Comparison of OPS imaging and conventional capillary microscopy to study the human microcirculation. Journal of applied physiology (Bethesda, Md. : 1985). 2001 Academic Article GET IT
Times cited: 144
Interobserver and intraobserver reproducibility of peripheral blood and oxygen pressure measurements in the assessment of lower extremity arterial disease. Journal of vascular surgery. 2001 Academic Article GET IT
Times cited: 106
The diagnosis of deep venous thrombosis using laser Doppler skin perfusion measurements. Microvascular research. 2001 Academic Article GET IT
Times cited: 6
The usefulness of a laser Doppler in the measurement of toe blood pressures. Journal of vascular surgery. 2000 Academic Article GET IT
Times cited: 47
Optimisation of the non-invasive assessment of critical limb ischaemia requiring invasive treatment. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 2000 Academic Article GET IT
Times cited: 21
Influence of repetitive finger puncturing on skin perfusion and capillary blood analysis in patients with diabetes mellitus. Clinical chemistry. 1999 Academic Article GET IT
Times cited: 4

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Background

education and training

M.D., University of Maastricht Faculty of Health, Medicine and Life Sciences (Netherlands) 96
Ph.D., University of Amsterdam (Netherlands) 2003

Contact

full name

Jurgen C. de Graaff

primary email

jcd4001@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Jurgen C. de Graaff Associate Professor of Clinical Anesthesiology

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage