J David Warren   Adjunct Associate Professor of Research in Biochemistry

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J David Warren, Ph.D., is an experienced researcher in the field of bioorganic and medicinal chemistry, who has placed several compounds into advanced preclinical development. His accomplishments include the development of methodology that allows for the total chemical synthesis of fully glycosylated proteins; the synthesis and application of new photostable fluorophores; the development of novel therapeutics for the treatment of Niemann-Pick type C (NPC) disease; the discovery of nucleoside analogs active against adenosine kinase; the discovery of selective inhibitors of HCN1 for the treatment of neuropathic pain; the discovery of novel PET tracers for imaging the chemokine receptor CXCR4; the identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancer; the discovery and development of inhibitors selective for mycobacterial versus human proteasomes; and the CURE-PRO platform, an innovative new approach to targeted protein degradation.

David is an Adjunct Associate Professor of Research in Biochemistry and former Director of the Milstein Chemistry Core Facility at Weill Cornell Medicine in New York City. He received his Ph.D. from Colorado State University, where he was awarded a graduate fellowship from Boehringer Ingelheim, and carried out postdoctoral studies under the tutelage of Dr. Samuel J. Danishefsky at the Memorial Sloan-Kettering Cancer Center as an NIH-supported fellow. He currently sits on the Scientific Advisory Board of Akelos, Inc., and is a scientific advisor for several small biopharmaceutical companies. He holds 10 issued US and international patents and has published over 48 peer-reviewed publications and book chapters.

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Contact

full name

  • J David Warren

primary email

  • jdw2003@med.cornell.edu

additional emails

  • david.warren@mac.com

Identity

eRA Commons ID

  •  davidwarren

External Relationships

externalRelationships

  • Relationships and collaborations with for-profit and not-for-profit organizations are of vital importance to our faculty because these exchanges of scientific information foster innovation. As experts in their fields, WCM physicians and scientists are sought after by many organizations to consult and educate. WCM and its faculty make this information available to the public, thus creating a transparent environment.

    Ownership refers to any financial stake an individual owns in any company (e.g., stock options, equity interest)Ownership:
    Akelos, Inc.
    Proprietary Interest refers to ownership of intellectual property rights (e.g., trademarks, patents, royalty income)Proprietary Interest:
    Akelos, Inc.