Gerhardt, Jeannine

Publications

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selected publications

Parent-of-origin-specific DNA replication timing is confined to large imprinted regions. Cell reports. 2024 Academic Article GET IT
DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility. Nature communications. 2024 Academic Article GET IT
DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility. 2024 GET IT
Visualizing DNA replication by single-molecule analysis of replicated DNA. STAR protocols. 2023 Academic Article GET IT
The discovery of simple repeats that cause complex disorders. Nature reviews. Molecular cell biology. 2023 Academic Article GET IT
Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells. Molecular cell. 2022 Academic Article GET IT
High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster. Nature medicine. 2022 Academic Article GET IT
The genetic architecture of DNA replication timing in human pluripotent stem cells. Nature communications. 2021 Academic Article GET IT
Times cited: 20
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components. The Journal of cell biology. 2021 Academic Article GET IT
Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability. Cancers. 2020 Information Resource GET IT
Times cited: 62
Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication. The Journal of cell biology. 2020 Academic Article GET IT
Times cited: 13
Human DNA Helicase B as a Candidate for Unwinding Secondary CGG Repeat Structures at the Fragile X Mental Retardation Gene. Frontiers in molecular neuroscience. 2018 Academic Article GET IT
Times cited: 6
CGG repeat length and AGG interruptions as indicators of fragile X-associated diminished ovarian reserve. Genetics in medicine : official journal of the American College of Medical Genetics. 2017 Academic Article GET IT
Times cited: 10
Fragile X-Associated Diminished Ovarian Reserve and Primary Ovarian Insufficiency from Molecular Mechanisms to Clinical Manifestations. Frontiers in molecular neuroscience. 2017 Information Resource GET IT
Times cited: 58
Replication Through Repetitive DNA Elements and Their Role in Human Diseases. 2017 GET IT
Times cited: 17
FANCD2 Facilitates Replication through Common Fragile Sites. Molecular cell. 2016 Academic Article GET IT
Times cited: 134
Notch hyper-activation drives trans-differentiation of hESC-derived endothelium. Stem cell research. 2016 Academic Article GET IT
Times cited: 8
Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells. Cell reports. 2016 Academic Article GET IT
Times cited: 46
Epigenetic modifications in human fragile X pluripotent stem cells; Implications in fragile X syndrome modeling. Brain research. 2015 Review GET IT
Times cited: 9
Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin. Experimental cell research. 2015 Academic Article GET IT
Times cited: 17
Cis-acting DNA sequence at a replication origin promotes repeat expansion to fragile X full mutation. The Journal of cell biology. 2014 Academic Article GET IT
Times cited: 38
Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome. Science (New York, N.Y.). 2014 Academic Article GET IT
Times cited: 237
The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells. Molecular cell. 2013 Academic Article GET IT
Times cited: 83
Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cells. Journal of virology. 2008 Academic Article GET IT
Times cited: 89
An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene. Molecular and cellular biology. 2006 Academic Article GET IT
Times cited: 42
Identification of new human origins of DNA replication by an origin-trapping assay. Molecular and cellular biology. 2006 Academic Article GET IT
Times cited: 36
Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. Journal of cell science. 2003 Academic Article GET IT
Times cited: 95

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Research

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Funding awarded

Repetitive sequences causing genomic instability and cell dysfunction awarded by National Institute of General Medical Sciences Principal Investigator 2024 - 2028
Repetitive sequences causing genomic instability and cell dysfunction awarded by National Institute of General Medical Sciences Principal Investigator 2024 - 2028
Environmental factors and compounds affecting the genomic stability in haploinsufficient BRCA1 cells. awarded by National Institute of Environmental Health Sciences Principal Investigator 2023 - 2026

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Background

education and training

Ph.D., Ludwig Maximilian University of Munich (Germany) 2005
M.S., Friedrich Schiller University (Germany) 2001

Contact

full name

Jeannine Gerhardt

primary email

jeg2039@med.cornell.edu

VIVO Weill Cornell Medical College

Jeannine Gerhardt Associate Professor of Stem Cell Biology in Obstetrics and Gynecology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email