selected publications
- JAK2V617F impairs lymphoid differentiation in myeloproliferative neoplasms. Leukemia. 2024 Academic Article GET IT
- Transplant Outcomes in Myelofibrosis: Impact of Donor Type [Cord Blood Grafts Supported by CD34+ selected Cells (Haplo-Cord) vs Matched Donors]. Transplantation and cellular therapy. 2024 Academic Article GET IT
- Are thrombosis, progression, and survival in ET predictable?. Blood cancer journal. 2024 Letter GET IT
- Mapping genotypes to chromatin accessibility profiles in single cells. Nature. 2024 Academic Article GET IT
- MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023 Academic Article GET IT
- Splenomegaly (SPML) in polycythemia vera (PV): its clinical significance and its relation to symptoms, post-polycythemic myelofibrosis (PPMF) and survival. Leukemia. 2022 Academic Article GET IT
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Expression of ENaC subunits in epithelia.
The Journal of general physiology.
2022
Academic Article
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Times cited: 4 - PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry. Cancer discovery. 2022 Academic Article GET IT
- Excess mortality in younger patients with myeloproliferative neoplasms. Leukemia & lymphoma. 2022 Letter GET IT
- Defining disease modification in myelofibrosis in the era of targeted therapy. Cancer. 2022 Review GET IT
- Normal life expectancy for polycythemia vera (PV) patients is possible. Leukemia. 2021 Academic Article GET IT
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Reversal of emphysema by restoration of pulmonary endothelial cells.
The Journal of experimental medicine.
2021
Academic Article
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Times cited: 40 -
Androgen receptor variant shows heterogeneous expression in prostate cancer according to differentiation stage.
Communications biology.
2021
Academic Article
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Times cited: 5 -
Interferon-alpha for treating polycythemia vera yields improved myelofibrosis-free and overall survival.
Leukemia.
2021
Academic Article
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Times cited: 66 -
Hepcidin Is Essential for Alveolar Macrophage Function and Is Disrupted by Smoke in a Murine Chronic Obstructive Pulmonary Disease Model.
Journal of immunology (Baltimore, Md. : 1950).
2020
Academic Article
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Times cited: 13 -
Megakaryocyte TGFβ1 partitions erythropoiesis into immature progenitor/stem cells and maturing precursors.
Blood.
2020
Academic Article
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Times cited: 9 -
Ruxolitinib can cause weight gain by blocking leptin signaling in the brain via JAK2/STAT3.
Blood.
2020
Article
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Times cited: 5 -
Incremental Utility of Right Ventricular Dysfunction in Patients With Myeloproliferative Neoplasm-Associated Pulmonary Hypertension.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.
2019
Academic Article
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Times cited: 13 -
Disease progression in myeloproliferative neoplasms: comparing patients in accelerated phase with those in chronic phase with increased blasts (<10%) or with other types of disease progression.
Haematologica.
2019
Article
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Times cited: 8 -
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature.
2019
Academic Article
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Times cited: 174 -
Adoptive Immunotherapy with Cord Blood for the Treatment of Refractory Acute Myelogenous Leukemia: Feasibility, Safety, and Preliminary Outcomes.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2018
Academic Article
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Times cited: 2 -
Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia.
Haematologica.
2018
Academic Article
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Times cited: 32 -
CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine.
Leukemia & lymphoma.
2017
Academic Article
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Times cited: 11 -
Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
Nature.
2017
Academic Article
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Times cited: 165 -
Sox17 drives functional engraftment of endothelium converted from non-vascular cells.
Nature communications.
2017
Academic Article
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Times cited: 18 -
Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem Cells.
Cancer cell.
2016
Academic Article
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Times cited: 104 -
Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
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Times cited: 51 -
Transplantation of Endothelial Cells to Mitigate Acute and Chronic Radiation Injury to Vital Organs.
Radiation research.
2016
Review
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Times cited: 19 -
KRAS AND THE REALITY OF PERSONALIZED MEDICINE IN NON-SMALL CELL LUNG CANCER.
Molecular medicine (Cambridge, Mass.).
2016
Academic Article
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Times cited: 14 -
Allogeneic Transplantation for Patients With Advanced Myelofibrosis: Splenomegaly and High Serum LDH are Adverse Risk Factors for Successful Engraftment.
Clinical lymphoma, myeloma & leukemia.
2016
Academic Article
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Times cited: 10 -
Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression.
Molecular & cellular oncology.
2015
Information Resource
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Times cited: 4 -
An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency.
The Journal of biological chemistry.
2014
Academic Article
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Times cited: 26 -
Activation of the vascular niche supports leukemic progression and resistance to chemotherapy.
Experimental hematology.
2014
Academic Article
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Times cited: 47 -
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature.
2014
Academic Article
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Times cited: 186 -
Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance.
Cancer cell.
2014
Academic Article
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Times cited: 192 -
The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.
Genes & development.
2014
Academic Article
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Times cited: 40 -
A phase I study of CPX-351 in combination with busulfan and fludarabine conditioning and allogeneic stem cell transplantation in adult patients with refractory acute leukemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2013
Academic Article
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Times cited: 12 -
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
The Journal of experimental medicine.
2013
Academic Article
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Times cited: 75 -
Decitabine in patients with newly diagnosed and relapsed acute myeloid leukemia.
Leukemia & lymphoma.
2013
Academic Article
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Times cited: 139 -
RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.
Journal of cell science.
2012
Academic Article
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Times cited: 52 -
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.
Nature medicine.
2012
Academic Article
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Times cited: 175 -
Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells.
Blood.
2012
Academic Article
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Times cited: 84 -
Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 27 -
Are low-intensity induction strategies better for older patients with acute myeloid leukemia?.
Leukemia research.
2012
Academic Article
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Times cited: 8 -
Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas.
Cancer discovery.
2011
Academic Article
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Times cited: 107 -
Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.
Blood.
2011
Academic Article
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Times cited: 118 -
DNA methylation of the first exon is tightly linked to transcriptional silencing.
PloS one.
2011
Academic Article
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Times cited: 481 -
Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid.
The Journal of biological chemistry.
2010
Academic Article
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Times cited: 81 -
Tumor promoting properties of the ETS protein MEF in ovarian cancer.
Oncogene.
2007
Academic Article
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Times cited: 27 - Advances in the molecular genetics of acute leukemia. Current oncology reports. 2005 Information Resource GET IT
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Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells.
Genes, chromosomes & cancer.
2004
Academic Article
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Times cited: 34 -
Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.
Proceedings of the National Academy of Sciences of the United States of America.
2004
Academic Article
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Times cited: 208 -
The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).
The Journal of biological chemistry.
2003
Academic Article
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Times cited: 82 -
Structural and functional characterization of platelet receptor-mediated factor VIII binding.
The Journal of biological chemistry.
2000
Academic Article
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Times cited: 48 -
The mechanism by which heparin promotes the inhibition of coagulation factor XIa by protease nexin-2.
The Journal of biological chemistry.
1997
Academic Article
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Times cited: 20 -
Progress curve analysis of the kinetics with which blood coagulation factor XIa is inhibited by protease nexin-2.
Biochemistry.
1997
Academic Article
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Times cited: 40 -
A binding site expressed on the surface of activated human platelets is shared by factor X and prothrombin.
Biochemistry.
1996
Academic Article
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Times cited: 59 -
Factor X bound to the surface of activated human platelets is preferentially activated by platelet-bound factor IXa.
Biochemistry.
1996
Academic Article
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Times cited: 35