selected publications
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Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.
Proceedings of the National Academy of Sciences of the United States of America.
2024
Academic Article
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Times cited: 3 - LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase. 2023 GET IT
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LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
Cancer discovery.
2023
Academic Article
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Times cited: 25 -
Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.
Cell reports.
2022
Academic Article
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Times cited: 26 - GCN2 kinase activation by ATP-competitive kinase inhibitors. Nature chemical biology. 2021 Academic Article GET IT
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Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.
eLife.
2018
Academic Article
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Times cited: 82 -
Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.
Proceedings of the National Academy of Sciences of the United States of America.
2018
Academic Article
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Times cited: 65 -
Second site mutation in the virus envelope expands the host range of a cytopathic variant of Moloney murine leukemia virus.
Virology.
2012
Academic Article
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Times cited: 6 -
Removal of either N-glycan site from the envelope receptor binding domain of Moloney and Friend but not AKV mouse ecotropic gammaretroviruses alters receptor usage.
Virology.
2009
Academic Article
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Times cited: 7