Kirou, Kyriakos

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Sustained depression of B cell counts in lupus nephritis after treatment with rituximab and/or belimumab is associated with fewer disease flares. Lupus. 2024 Academic Article GET IT
Standing on Shoulders: Interferon Research From Viral Interference to Lupus Pathogenesis and Treatment. Arthritis & rheumatology (Hoboken, N.J.). 2024 Review GET IT
Low Peripheral B-Cell Counts in Patients With Systemic Rheumatic Diseases Due to Treatment With Belimumab and/or Rituximab Are Associated With Low Antibody Responses to Primary COVID-19 Vaccination. HSS journal : the musculoskeletal journal of Hospital for Special Surgery. 2022 Academic Article GET IT
Type I interferon and neutrophil transcripts in lupus nephritis renal biopsies: Clinical and histopathological associations. Rheumatology (Oxford, England). 2022 Academic Article GET IT
Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses. The Journal of experimental medicine. 2022 Academic Article GET IT
Times cited: 26
Belimumab or anifrolumab for systemic lupus erythematosus? A risk-benefit assessment. Frontiers in immunology. 2022 Review GET IT
Times cited: 19
Venous Thromboembolic Events in African American Lupus Patients in Association With Antiphospholipid Antibodies Compared to White Patients. Arthritis care & research. 2022 Academic Article GET IT
A case of inflammatory cerebral amyloid angiopathy after ischemic stroke - a potential risk factor related to blood-brain barrier disruption. Clinical imaging. 2021 Review GET IT
Times cited: 4
Evaluation of a Patient-Reported Frailty Tool in Women with Systemic Lupus Erythematosus. The Journal of rheumatology. 2021 Academic Article GET IT
Risk factors for multi-joint disease in patients with glucocorticoid-induced osteonecrosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2021 Academic Article GET IT
Expression of APOBEC family members as regulators of endogenous retroelements and malignant transformation in systemic autoimmunity. Clinical immunology (Orlando, Fla.). 2020 Academic Article GET IT
Times cited: 3
Phase II Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis. Arthritis & rheumatology (Hoboken, N.J.). 2020 Academic Article GET IT
Times cited: 131
Responsiveness of the Patient-Reported Outcomes Measurement Information System Global Health Short Form in Outpatients With Systemic Lupus Erythematosus. Arthritis care & research. 2020 Academic Article GET IT
Times cited: 7
Type I Interferons in Autoimmune Disease. Annual review of pathology. 2018 Review GET IT
Times cited: 101
Feasibility of Patient-Reported Outcomes Measurement Information System (PROMIS®) computerized adaptive tests in systemic lupus erythematosus outpatients. Lupus. 2018 Academic Article GET IT
Times cited: 7
Feasibility, Validity, and Reliability of the 10-item Patient Reported Outcomes Measurement Information System Global Health Short Form in Outpatients with Systemic Lupus Erythematosus. The Journal of rheumatology. 2018 Academic Article GET IT
Times cited: 42
Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8. Science translational medicine. 2018 Academic Article GET IT
Times cited: 81
Defective regulation of L1 endogenous retroelements in primary Sjogren's syndrome and systemic lupus erythematosus: Role of methylating enzymes. Journal of autoimmunity. 2017 Academic Article GET IT
Times cited: 67
Validity and Reliability of Patient Reported Outcomes Measurement Information System Computerized Adaptive Tests in Systemic Lupus Erythematosus. The Journal of rheumatology. 2017 Academic Article GET IT
Times cited: 22
Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE. Annals of the rheumatic diseases. 2016 Academic Article GET IT
Times cited: 71
Expression of Long Interspersed Nuclear Element 1 Retroelements and Induction of Type I Interferon in Patients With Systemic Autoimmune Disease. Arthritis & rheumatology (Hoboken, N.J.). 2016 Academic Article GET IT
Times cited: 148
Novel molecular signatures in mononuclear cell populations from patients with systemic lupus erythematosus. Clinical immunology (Orlando, Fla.). 2016 Academic Article GET IT
Times cited: 11
Minimal Change Disease as a Secondary and Reversible Event of a Renal Transplant Case with Systemic Lupus Erythematosus. Case reports in nephrology. 2015 Academic Article GET IT
Interferon-α and angiogenic dysregulation in pregnant lupus patients who develop preeclampsia. Arthritis & rheumatology (Hoboken, N.J.). 2015 Academic Article GET IT
Times cited: 62
Identification of Candidate Predictors of Lupus Flare. Transactions of the American Clinical and Climatological Association. 2015 Review GET IT
Times cited: 2
Targeting of type I interferon in systemic autoimmune diseases. Translational research : the journal of laboratory and clinical medicine. 2014 Information Resource GET IT
Times cited: 93
Cell-bound complement activation products in systemic lupus erythematosus: comparison with anti-double-stranded DNA and standard complement measurements. Lupus science & medicine. 2014 Academic Article GET IT
Times cited: 68
Measuring interferon alpha and other cytokines in SLE. Methods in molecular biology (Clifton, N.J.). 2014 Academic Article GET IT
Times cited: 4
A surge in anti-dsDNA titer predicts a severe lupus flare within six months. Lupus. 2013 Academic Article GET IT
Times cited: 25
Increased serum type I interferon activity in organ-specific autoimmune disorders: clinical, imaging, and serological associations. Frontiers in immunology. 2013 Academic Article GET IT
Times cited: 17
Enhanced rho-associated protein kinase activation in patients with systemic lupus erythematosus. Arthritis and rheumatism. 2013 Academic Article GET IT
Times cited: 53
Two systemic lupus erythematosus patients with severe pleurisy: similar presentations, different causes. 2013 GET IT
Times cited: 2
Anti-interferon alpha treatment in SLE. Clinical immunology (Orlando, Fla.). 2013 Information Resource GET IT
Times cited: 90
Measurement of cell-bound complement activation products enhances diagnostic performance in systemic lupus erythematosus. Arthritis and rheumatism. 2012 Academic Article GET IT
Times cited: 47
Antiinflammatory strategies, not just B cell depletion, are required for optimal therapy for severe proliferative lupus nephritis: comment on the article by Rovin et al. Arthritis and rheumatism. 2012 Article GET IT
Times cited: 1
Research studies and their implications for social work practice in a multidisciplinary center for lupus care. Social work in health care. 2012 Academic Article GET IT
Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps. Arthritis and rheumatism. 2011 Academic Article GET IT
Times cited: 110
Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study. Annals of the rheumatic diseases. 2011 Academic Article GET IT
Times cited: 187
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients. Journal of immunology (Baltimore, Md. : 1950). 2011 Academic Article GET IT
Times cited: 134
A 26-year-old white man with a systemic lupus erythematosus flare and acute multiorgan ischemia: Vasculitis or thrombosis?. Arthritis care & research. 2011 Conference Paper GET IT
Times cited: 2
Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial. Annals of the rheumatic diseases. 2011 Academic Article GET IT
Times cited: 160
Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients. Arthritis and rheumatism. 2010 Academic Article GET IT
Times cited: 100
Cyclophosphamide responsive interstitial lung disease in "overlap syndrome": a clinical pathology conference held by the division of rheumatology at the hospital for special surgery. HSS journal : the musculoskeletal journal of Hospital for Special Surgery. 2010 Academic Article GET IT
A new tool for detection of type I interferon activation in systemic lupus erythematosus. Arthritis research & therapy. 2010 Editorial Article GET IT
Times cited: 5
Age- and gender-specific modulation of serum osteopontin and interferon-alpha by osteopontin genotype in systemic lupus erythematosus. Genes and immunity. 2009 Academic Article GET IT
Times cited: 95
Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 208
Interferon-induced versus chemokine transcripts as lupus biomarkers. Arthritis research & therapy. 2008 Editorial Article GET IT
Times cited: 9
Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies. Arthritis and rheumatism. 2006 Academic Article GET IT
Times cited: 230
Elevated levels of soluble CD40 ligand (sCD40L) in serum of patients with systemic autoimmune diseases. Journal of autoimmunity. 2006 Academic Article GET IT
Times cited: 103
Soluble mediators as therapeutic targets in systemic lupus erythematosus: cytokines, immunoglobulin receptors, and the complement system. Rheumatic diseases clinics of North America. 2006 Information Resource GET IT
Times cited: 14
Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. Arthritis and rheumatism. 2005 Academic Article GET IT
Times cited: 477
Cytokine-mediated regulation of activating and inhibitory Fc gamma receptors in human monocytes. Journal of leukocyte biology. 2005 Academic Article GET IT
Times cited: 56
Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus. Arthritis and rheumatism. 2004 Academic Article GET IT
Times cited: 306
Interferon-alpha in systemic lupus erythematosus. Current opinion in rheumatology. 2004 Information Resource GET IT
Times cited: 118
Measurement of cytokines in autoimmune disease. Methods in molecular medicine. 2004 Academic Article GET IT
Times cited: 11
Microarray analysis of interferon-regulated genes in SLE. Autoimmunity. 2003 Information Resource GET IT
Times cited: 215
T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells. Journal of immunology (Baltimore, Md. : 1950). 2002 Academic Article GET IT
Times cited: 38
Effect of transketolase modifications on carbon flow to the purine-nucleotide pathway in Corynebacterium ammoniagenes. Applied microbiology and biotechnology. 2001 Academic Article GET IT
Times cited: 26
Regulation of CD40 ligand expression in systemic lupus erythematosus. Current opinion in rheumatology. 2001 Information Resource GET IT
Times cited: 54
Induction of Fas ligand-mediated apoptosis by interferon-alpha. Clinical immunology (Orlando, Fla.). 2000 Academic Article GET IT
Times cited: 57
Sarcoidosis presenting with large vessel vasculitis and osteosclerosis-related bone and joint pain. 2000 GET IT
Times cited: 4
Elevated levels and functional capacity of soluble CD40 ligand in systemic lupus erythematosus sera. Arthritis and rheumatism. 1999 Academic Article GET IT
Times cited: 137
New pieces to the SLE cytokine puzzle. Clinical immunology (Orlando, Fla.). 1999 Editorial Article GET IT
Times cited: 22

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Background

education and training

D.Sc., Nagasaki University School of Medicine (Japan) 2002
M.D., Aristotle University of Thessaloniki Faculty of Medicine (Greece) 1988

Contact

full name

Kyriakos Kirou

primary email

kyk2001@med.cornell.edu
kirouk@hss.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Kyriakos Kirou Associate Professor of Clinical Medicine

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage