Lange, Dale J.

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Heuristic scoring method utilizing FDG-PET statistical parametric mapping in the evaluation of suspected Alzheimer disease and frontotemporal lobar degeneration. American journal of nuclear medicine and molecular imaging. 2021 Academic Article GET IT
Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. JAMA neurology. 2021 Academic Article GET IT
Times cited: 87
A specific biomarker for amyotrophic lateral sclerosis: Quantitative susceptibility mapping. Clinical imaging. 2021 Academic Article GET IT
Times cited: 1
Clinical care and therapeutic trials in PLS. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2020 Academic Article GET IT
Times cited: 6
Preface: promoting research in PLS: current knowledge and future challenges. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2020 Editorial Article GET IT
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia. Cell reports. 2019 Academic Article GET IT
Times cited: 165
The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension. Acta neuropathologica. 2019 Academic Article GET IT
Times cited: 16
Diffusion tensor imaging and quantitative susceptibility mapping as diagnostic tools for motor neuron disorders. Clinical imaging. 2018 Academic Article GET IT
Times cited: 9
Pyrimethamine significantly lowers cerebrospinal fluid Cu/Zn superoxide dismutase in amyotrophic lateral sclerosis patients with SOD1 mutations. Annals of neurology. 2017 Academic Article GET IT
Times cited: 30
Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2016 Academic Article GET IT
Times cited: 15
Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients. PloS one. 2016 Academic Article GET IT
Times cited: 20
Quantitative susceptibility mapping of the motor cortex in amyotrophic lateral sclerosis and primary lateral sclerosis. AJR. American journal of roentgenology. 2015 Academic Article GET IT
Times cited: 63
Safety, pharmacokinetic, and functional effects of the nogo-a monoclonal antibody in amyotrophic lateral sclerosis: a randomized, first-in-human clinical trial. PloS one. 2014 Academic Article GET IT
Times cited: 43
Motor cortex glutathione deficit in ALS measured in vivo with the J-editing technique. Neuroscience letters. 2014 Academic Article GET IT
Times cited: 72
Can white matter changes occur in disorders of peripheral nerve hyperexcitability?. Multiple sclerosis and related disorders. 2013 Academic Article GET IT
Diagnostic biopsy of the pronator teres and a motor branch of the median nerve: indications and technique. The Journal of hand surgery. 2012 Academic Article GET IT
Times cited: 9
Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease. PloS one. 2012 Academic Article GET IT
Times cited: 102
Pyrimethamine decreases levels of SOD1 in leukocytes and cerebrospinal fluid of ALS patients: a phase I pilot study. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2012 Academic Article GET IT
Times cited: 26
Differential gene expression in patients with amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 2011 Academic Article GET IT
Times cited: 20
Do A-waves help predict intravenous immunoglobulin response in multifocal motor neuropathy without block?. Muscle & nerve. 2011 Academic Article GET IT
Times cited: 1
A randomized study of alglucosidase alfa in late-onset Pompe's disease. The New England journal of medicine. 2010 Academic Article GET IT
Times cited: 511
ALSFRS and appel ALS scores: discordance with disease progression. Muscle & nerve. 2008 Academic Article GET IT
Times cited: 25
Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis. International journal of medical sciences. 2008 Academic Article GET IT
Times cited: 50
Measures of dyspnea in patients with amyotrophic lateral sclerosis. Muscle & nerve. 2007 Academic Article GET IT
Times cited: 9
High-frequency chest wall oscillation in ALS: an exploratory randomized, controlled trial. Neurology. 2006 Academic Article GET IT
Times cited: 53
A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis. BMC neuroscience. 2006 Academic Article GET IT
Times cited: 244
Identification of potential CSF biomarkers in ALS. Neurology. 2006 Academic Article GET IT
Times cited: 175
Inclusion body myositis mimicking motor neuron disease. Archives of neurology. 2001 Academic Article GET IT
Times cited: 68
Reduction of paclitaxel-induced peripheral neuropathy with glutamine. Clinical cancer research : an official journal of the American Association for Cancer Research. 2001 Academic Article GET IT
Times cited: 133
Motor neuron diseases: comparison of single-voxel proton MR spectroscopy of the motor cortex with MR imaging of the brain. Radiology. 1999 Academic Article GET IT
Times cited: 88
Selegiline is ineffective in a collaborative double-blind, placebo-controlled trial for treatment of amyotrophic lateral sclerosis. Archives of neurology. 1998 Academic Article GET IT
Times cited: 61
The role of quantitative electromyography in inclusion body myositis. Journal of neurology, neurosurgery, and psychiatry. 1997 Academic Article GET IT
Assessment: dermatomal somatosensory evoked potentials. Report of the American Academy of Neurology's Therapeutics and Technology Assessments Subcommittee. Neurology. 1997 Academic Article GET IT
Times cited: 13
Complications of intravenous immune globulin treatment in neurologic disease. Neurology. 1997 Letter GET IT
Diagnostic biopsy of the motor nerve to the gracilis muscle. Technical note. Journal of neurosurgery. 1997 Academic Article GET IT
Times cited: 7
Erroneous diagnosis corrected after 28 years. Not spinal muscular atrophy with ophthalmoplegia but minicore myopathy. 1996 GET IT
Times cited: 10
Motor neuron disease, lymphoproliferative disease, and bone marrow biopsy. Muscle & nerve. 1996 Academic Article GET IT
Times cited: 22
Recombinant human insulin-like growth factor-I in ALS: description of a double-blind, placebo-controlled study. North American ALS/IGF-I Study Group. Neurology. 1996 Academic Article GET IT
Times cited: 50
Complications of intravenous immune globulin treatment in neurologic disease. Neurology. 1996 Academic Article GET IT
Times cited: 200
Anti-MAG and anti-SGPG antibodies in neuropathy. Muscle & nerve. 1996 Academic Article GET IT
Times cited: 102
Blood superoxide dismutase, catalase and glutathione peroxidase activities in familial and sporadic amyotrophic lateral sclerosis. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. 1996 Academic Article GET IT
Times cited: 47
Post-polio muscular atrophy. An electrophysiological study of motor unit architecture. Annals of the New York Academy of Sciences. 1995 Academic Article GET IT
Times cited: 7
Training guidelines for the use of botulinum toxin for the treatment of neurologic disorders. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 1994 Guideline GET IT
Times cited: 40
Clinical and electrophysiologic correlates of elevated anti-GM1 antibody titers. Neurology. 1994 Academic Article GET IT
Times cited: 67
Assessment: melodic intonation therapy. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 1994 Academic Article GET IT
Times cited: 48
Do GM1 antibodies induce demyelination?. Muscle & nerve. 1994 Academic Article GET IT
Times cited: 21
Persistent and transient "conduction block" in motor neuron diseases. Muscle & nerve. 1993 Academic Article GET IT
Times cited: 37
Distant effects of locally injected botulinum toxin: a double-blind study of single fiber EMG changes. Muscle & nerve. 1993 Letter GET IT
Times cited: 4
Motor neuron diseases and amyotrophic lateral sclerosis: GM1 antibodies and paraproteinemia. Neurology. 1993 Academic Article GET IT
Times cited: 36
Spinal root and proximal nerve stimulation. Advances in neurology. 1993 Review GET IT
Times cited: 1
Neuropathies. Current opinion in neurology and neurosurgery. 1992 Review GET IT
Times cited: 1
Single fiber electromyography in normal subjects: reproducibility, variability, and technical considerations. Electromyography and clinical neurophysiology. 1992 Academic Article GET IT
Times cited: 11
Multifocal motor neuropathy with conduction block: is it a distinct clinical entity?. Neurology. 1992 Academic Article GET IT
Times cited: 152
Sensory nerve abnormalities in brachial plexopathy. European neurology. 1992 Academic Article GET IT
Times cited: 9
Chronic inflammatory demyelinating polyneuropathy in childhood: clinical and electrophysiological features. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 1991 Academic Article GET IT
Times cited: 23
Distant effects of locally injected botulinum toxin: a double-blind study of single fiber EMG changes. Muscle & nerve. 1991 Academic Article GET IT
Times cited: 138
Lymphoma, motor neuron diseases, and amyotrophic lateral sclerosis. Annals of neurology. 1991 Academic Article GET IT
Times cited: 117
X-linked spinal muscular atrophy (Kennedy's syndrome). A kindred with hypobetalipoproteinemia. Archives of neurology. 1990 Academic Article GET IT
Times cited: 30
Motor neuron disease and amyotrophic lateral sclerosis: relation of high CSF protein content to paraproteinemia and clinical syndromes. Neurology. 1990 Academic Article GET IT
Times cited: 115
Long-duration polyphasic motor unit potentials in myopathies: a quantitative study with pathological correlation. Muscle & nerve. 1990 Academic Article GET IT
Times cited: 60
Disorders of peripheral nerves associated with HIV infection. Clinics in podiatric medicine and surgery. 1990 Information Resource GET IT
Times cited: 4
Infectious agents and disease of peripheral nerve. Clinics in podiatric medicine and surgery. 1990 Information Resource GET IT
Neuromuscular involvement in mild, asymptomatic primary hyperparathyroidism. The American journal of medicine. 1989 Academic Article GET IT
Times cited: 96
Ring finger testing in carpal tunnel syndrome: a comparative study of diagnostic utility. Muscle & nerve. 1989 Academic Article GET IT
Times cited: 125
Postpolio muscular atrophy. Diagnostic utility of macroelectromyography. Archives of neurology. 1989 Academic Article GET IT
Times cited: 28
The neuromuscular manifestations of human immunodeficiency virus infections. Archives of neurology. 1988 Academic Article GET IT
Times cited: 81
Seronegative myasthenia gravis. Neurology. 1988 Academic Article GET IT
Times cited: 135
Distant effects of locally injected botulinum toxin: incidence and course. Advances in neurology. 1988 Academic Article GET IT
Times cited: 44
Distant effects of local injection of botulinum toxin. Muscle & nerve. 1987 Academic Article GET IT
Times cited: 135
Botulinum toxin (BOTOX) for the treatment of "spastic dysphonia" as part of a trial of toxin injections for the treatment of other cranial dystonias. The Laryngoscope. 1986 Letter GET IT
Times cited: 80
A therapeutic trial of gangliosides and thymosin in the Wobbler mouse model of motor neuron disease. Journal of the neurological sciences. 1983 Academic Article GET IT
Times cited: 24

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Background

education and training

M.D., New York Medical College 1978
B.S., Siena College 1974

Contact

full name

Dale J. Lange

primary email

langeda@med.cornell.edu

VIVO Weill Cornell Medical College

Dale J. Lange Professor of Neurology

Publications

selected publications

Background

education and training

Contact

full name

primary email