selected publications
- Overnutrition in the early postnatal period influences lifetime metabolic risk: Evidence for impact on pancreatic β-cell mass and function. Journal of diabetes investigation. 2024 Review GET IT
- Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting β cell differentiation. The Journal of clinical investigation. 2023 Academic Article GET IT
- The feasibility, acceptability, and usability of telehealth visits. Frontiers in medicine. 2023 Academic Article GET IT
- High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets. Scientific reports. 2022 Academic Article GET IT
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Weight Loss Outcomes With Telemedicine During COVID-19.
Frontiers in endocrinology.
2022
Academic Article
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Times cited: 11 - Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance. Nature communications. 2022 Academic Article GET IT
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Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
2021
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Times cited: 12 - Ergocalciferol in New-onset Type 1 Diabetes: A Randomized Controlled Trial. Journal of the Endocrine Society. 2021 Academic Article GET IT
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Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Cell metabolism.
2021
Academic Article
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Times cited: 141 - Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse β-Cells. Frontiers in endocrinology. 2021 Academic Article GET IT
- Preadmission predictors of severe COVID-19 in patients with diabetes mellitus. Journal of diabetes and its complications. 2021 Academic Article GET IT
- In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR. Nature metabolism. 2021 Academic Article GET IT
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The Independent Risk of Obesity and Diabetes and Their Interaction in COVID-19: A Retrospective Cohort Study.
Obesity (Silver Spring, Md.).
2021
Academic Article
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Times cited: 20 - Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance. 2021 GET IT
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Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.
The Journal of biological chemistry.
2020
Academic Article
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Times cited: 32 -
Continuous glucose monitoring reduces pubertal hyperglycemia of type 1 diabetes.
Journal of pediatric endocrinology & metabolism : JPEM.
2020
Academic Article
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Times cited: 2 -
Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.
Science signaling.
2019
Academic Article
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Times cited: 40 -
Atf6α impacts cell number by influencing survival, death and proliferation.
Molecular metabolism.
2019
Information Resource
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Times cited: 26 -
Adipose tissue-derived free fatty acids initiate myeloid cell accumulation in mouse liver in states of lipid oversupply.
American journal of physiology. Endocrinology and metabolism.
2018
Academic Article
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Times cited: 14 -
ANRIL: A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease.
Frontiers in endocrinology.
2018
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Times cited: 144 - Pancreatic Islet Embedding for Paraffin Sections. Journal of visualized experiments : JoVE. 2018 Academic Article GET IT
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Children with type 1 diabetes who experienced a honeymoon phase had significantly lower LDL cholesterol 5 years after diagnosis.
PloS one.
2018
Academic Article
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Times cited: 20 -
CDKN2A/B T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets.
Diabetes.
2018
Academic Article
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Times cited: 48 -
Partial clinical remission in type 1 diabetes: a comparison of the accuracy of total daily dose of insulin of <0.3 units/kg/day to the gold standard insulin-dose adjusted hemoglobin A1c of ≤9 for the detection of partial clinical remission.
Journal of pediatric endocrinology & metabolism : JPEM.
2017
Academic Article
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Times cited: 14 -
A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes.
PloS one.
2017
Academic Article
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Times cited: 43 -
Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.
The Journal of biological chemistry.
2016
Academic Article
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Times cited: 15 -
Islet biology, the CDKN2A/B locus and type 2 diabetes risk.
Diabetologia.
2016
Information Resource
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Times cited: 76 -
In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.
Molecular therapy : the journal of the American Society of Gene Therapy.
2016
Academic Article
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Times cited: 100 -
PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.
Diabetes.
2016
Academic Article
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Times cited: 39 -
Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
Diabetes.
2016
Academic Article
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Times cited: 79 -
Insulin demand regulates β cell number via the unfolded protein response.
The Journal of clinical investigation.
2015
Academic Article
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Times cited: 160 -
Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
2015
Academic Article
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Times cited: 10 -
Evaluation, Medical Therapy, and Course of Adult Persistent Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass Surgery: A Case Series.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
2015
Academic Article
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Times cited: 15 -
β-catenin links hepatic metabolic zonation with lipid metabolism and diet-induced obesity in mice.
The American journal of pathology.
2014
Academic Article
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Times cited: 50 -
Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?.
Current diabetes reports.
2014
Information Resource
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Times cited: 102 -
Glucagon regulates hepatic kisspeptin to impair insulin secretion.
Cell metabolism.
2014
Academic Article
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Times cited: 177 -
Human β-cell regeneration: progress, hurdles, and controversy.
Current opinion in endocrinology, diabetes, and obesity.
2014
Information Resource
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Times cited: 12 -
The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.
PloS one.
2014
Academic Article
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Times cited: 37 -
Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice.
PloS one.
2013
Academic Article
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Times cited: 14 -
Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression.
American journal of physiology. Endocrinology and metabolism.
2013
Academic Article
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Times cited: 102 -
Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia.
European journal of applied physiology.
2012
Academic Article
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Times cited: 32 -
ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.
Diabetes.
2012
Academic Article
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Times cited: 97 -
Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.
Diabetes.
2012
Academic Article
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Times cited: 91 -
Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18.
Diabetes.
2012
Academic Article
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Times cited: 60 -
Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice.
Obesity (Silver Spring, Md.).
2012
Academic Article
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Times cited: 41 -
Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.
Diabetes.
2011
Academic Article
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Times cited: 38 -
Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.
Diabetes.
2010
Academic Article
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Times cited: 95 -
Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.
Diabetologia.
2010
Academic Article
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Times cited: 102 -
Hyperinsulinemia predicts survival in a hyperglycemic mouse model of critical illness.
Critical care medicine.
2009
Academic Article
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Times cited: 6 -
Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice.
The Journal of physiology.
2007
Academic Article
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Times cited: 104 -
Glucose infusion in mice: a new model to induce beta-cell replication.
Diabetes.
2007
Academic Article
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Times cited: 223 -
Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity.
American journal of respiratory and critical care medicine.
2007
Academic Article
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Times cited: 303 -
Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle.
The Journal of cell biology.
2005
Academic Article
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Times cited: 49 -
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.
The Journal of cell biology.
2003
Academic Article
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Times cited: 223 -
Stem cells in the skin: waste not, Wnt not.
Genes & development.
2003
Information Resource
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Times cited: 273 -
Molecular genetic and endocrine mechanisms of hair growth.
Hormone research.
2003
Information Resource
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Times cited: 45 -
Functional characterization of soluble and membrane-bound forms of vaccinia virus complement control protein (VCP).
Molecular immunology.
1999
Academic Article
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Times cited: 36 -
Utility of adenoviral-mediated Fas ligand gene transfer to modulate islet allograft survival.
Transplantation.
1998
Academic Article
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Times cited: 36 -
Helium-ion-induced human cataractogenesis.
Advances in space research : the official journal of the Committee on Space Research (COSPAR).
1994
Academic Article
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Times cited: 6