Saavedra, Lucas

Publications

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selected publications

Unlocking the regenerative properties of extraembryonic membrane-derived biomaterials in tissue engineering. Acta biomaterialia. 2025 Review GET IT
Acellular porcine placental membranes as a novel biomaterial for tissue repair applications. Frontiers in bioengineering and biotechnology. 2025 Academic Article GET IT
Fenofibrate treatment during lactation prevents liver and adipose tissue associated metabolic dysfunction in a rat model of childhood obesity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2025 Academic Article GET IT
Methylglyoxal Reshapes Hepatic and Adipose Tissue Metabolism and Increases Viability of Lymphocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2025 Academic Article GET IT
Maternal AGE Precursors During Lactation Alters Offspring Glycemic Homeostasis Early in Life. Biology. 2025 Academic Article GET IT
High-fat diet during lactation, as opposed to during adolescence or gestation, programs cardiometabolic and autonomic dysfunctions in adult offspring. Brain research. 2024 Academic Article GET IT
Times cited: 1
Hypertension induced by peri-pubertal protein restriction depends on renin-angiotensin system dysfunction in adult male rats. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2024 Academic Article GET IT
Epigenetic programming for obesity and noncommunicable disease: From womb to tomb. Reviews in endocrine & metabolic disorders. 2023 Review GET IT
Times cited: 8
Puberty as a DOHaD programming window: high-fat diet induces long-term hepatic dysfunction in male rats. Journal of developmental origins of health and disease. 2023 Academic Article GET IT
Times cited: 3
Postnatal Overfeeding in Rodents Induces a Neurodevelopment Delay and Anxious-like Behaviour Accompanied by Sex- and Brain-Region-Specific Synaptic and Metabolic Changes. Nutrients. 2023 Academic Article GET IT
Times cited: 6
Exposure to Obesogenic Environments during Perinatal Development Modulates Offspring Energy Balance Pathways in Adipose Tissue and Liver of Rodent Models. Nutrients. 2023 Academic Article GET IT
Times cited: 8
Protein-caloric restriction induced HPA axis activation and altered the milk composition imprint metabolism of weaned rat offspring. Nutrition (Burbank, Los Angeles County, Calif.). 2022 Academic Article GET IT
Times cited: 8
Protein Restriction in the Peri-Pubertal Period Induces Autonomic Dysfunction and Cardiac and Vascular Structural Changes in Adult Rats. Frontiers in physiology. 2022 Academic Article GET IT
Times cited: 10
Early postnatal exposure of rat pups to methylglyoxal induces oxidative stress, inflammation and dysmetabolism at adulthood. Journal of developmental origins of health and disease. 2022 Academic Article GET IT
Times cited: 2
Neonatal metformin short exposure inhibits male reproductive dysfunction caused by a high-fat diet in adult rats. Toxicology and applied pharmacology. 2021 Academic Article GET IT
Times cited: 3
Metformin Improves Autonomic Nervous System Imbalance and Metabolic Dysfunction in Monosodium L-Glutamate-Treated Rats. Frontiers in endocrinology. 2021 Academic Article GET IT
Times cited: 12
COVID-19 During Development: A Matter of Concern. Frontiers in cell and developmental biology. 2021 Academic Article GET IT
Times cited: 4
Early AGEing and metabolic diseases: is perinatal exposure to glycotoxins programming for adult-life metabolic syndrome?. Nutrition reviews. 2021 Review GET IT
Times cited: 6
Potential attenuation of early-life overfeeding-induced metabolic dysfunction by chronic maternal acetylcholinesterase inhibitor exposure. Toxicology. 2019 Academic Article GET IT
Times cited: 4
Moderate exercise training since adolescence reduces Walker 256 tumour growth in adult rats. The Journal of physiology. 2019 Academic Article GET IT
Times cited: 4
Environmental monitoring and the developmental origins of health and disease. Journal of developmental origins of health and disease. 2019 Review GET IT
Times cited: 51
Strength training reverses ovariectomy-induced bone loss and improve metabolic parameters in female Wistar rats. Life sciences. 2018 Academic Article GET IT
Times cited: 20
Malnutrition during late pregnancy exacerbates high-fat-diet-induced metabolic dysfunction associated with lower sympathetic nerve tonus in adult rat offspring. Nutritional neuroscience. 2018 Academic Article GET IT
Times cited: 14
Maternal low-protein diet during lactation combined with early overfeeding impair male offspring's long-term glucose homeostasis. Endocrine. 2018 Academic Article GET IT
Times cited: 7
Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats. Frontiers in physiology. 2018 Academic Article GET IT
Times cited: 20
A High Fat Diet during Adolescence in Male Rats Negatively Programs Reproductive and Metabolic Function Which Is Partially Ameliorated by Exercise. Frontiers in physiology. 2017 Academic Article GET IT
Times cited: 39
Methylglyoxal treatment in lactating mothers leads to type 2 diabetes phenotype in male rat offspring at adulthood. European journal of nutrition. 2016 Academic Article GET IT
Times cited: 22

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Research

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Funding awarded

Targeting glucocorticoid circadian rhythmicity for β-cell regeneration: neuroendocrine and intracellular pathways. awarded by American Diabetes Association, Inc. Principal Investigator 2026 - 2028

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Background

education and training

Ph.D., University of Coimbra (Portugal) 23
M.S., University of Coimbra (Portugal) 2019
B.S., UniCesumar (Brazil) 2017

Contact

full name

Lucas Saavedra

primary email

lps4001@med.cornell.edu

VIVO Weill Cornell Medical College

Lucas Saavedra Postdoctoral Associate in Biochemistry and Biophysics

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email