selected publications
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Objective Response Rate Among Patients With Locally Advanced or Metastatic Sarcoma Treated With Talimogene Laherparepvec in Combination With Pembrolizumab: A Phase 2 Clinical Trial.
JAMA oncology.
2020
Academic Article
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Times cited: 131 -
Pilot Trial AMC-063: Safety and Efficacy of Bortezomib in AIDS-associated Kaposi Sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 15 -
Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
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Times cited: 414 -
A Phase II Trial of Sorafenib and Dacarbazine for Leiomyosarcoma, Synovial Sarcoma, and Malignant Peripheral Nerve Sheath Tumors.
The oncologist.
2018
Academic Article
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Times cited: 15 -
A phase Ib study of BGJ398, a pan-FGFR kinase inhibitor in combination with imatinib in patients with advanced gastrointestinal stromal tumor.
Investigational new drugs.
2018
Academic Article
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Times cited: 33 -
PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence.
Oncogene.
2018
Academic Article
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Times cited: 33 -
ATRX is a regulator of therapy induced senescence in human cells.
Nature communications.
2017
Academic Article
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Times cited: 57 -
A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours.
European journal of cancer.
2017
Academic Article
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Times cited: 46 -
Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasatinib plus Ipilimumab.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
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Times cited: 107 -
Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma.
Journal of cancer research and clinical oncology.
2016
Academic Article
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Times cited: 11 -
TP53 mutations emerge with HDM2 inhibitor SAR405838 treatment in de-differentiated liposarcoma.
Nature communications.
2016
Academic Article
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Times cited: 74 -
Liposarcoma: Multimodality Management and Future Targeted Therapies.
Surgical oncology clinics of North America.
2016
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Times cited: 106 -
Phase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Academic Article
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Times cited: 129 -
Overall Survival and Response to Systemic Therapy in Metastatic Extrauterine Leiomyosarcoma.
Sarcoma.
2016
Academic Article
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Times cited: 10 -
Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity.
Cancer science.
2016
Academic Article
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Times cited: 17 - Reply to A. Indini et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Article GET IT
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Kaposi Sarcoma of Childhood: Inborn or Acquired Immunodeficiency to Oncogenic HHV-8.
Pediatric blood & cancer.
2015
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Times cited: 42 -
A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas.
The oncologist.
2015
Academic Article
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Times cited: 23 -
Impact of surgery, radiation and systemic therapy on the outcomes of patients with dendritic cell and histiocytic sarcomas.
European journal of cancer.
2015
Academic Article
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Times cited: 80 -
Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2015
Academic Article
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Times cited: 862 -
Outcomes of Systemic Therapy for Patients with Metastatic Angiosarcoma.
Oncology.
2015
Academic Article
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Times cited: 44 -
Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications.
The American journal of surgical pathology.
2015
Academic Article
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Times cited: 187 -
Phase II Trial of Gemcitabine and Docetaxel with Bevacizumab in Soft Tissue Sarcoma.
Sarcoma.
2015
Academic Article
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Times cited: 50 -
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.
Oncotarget.
2015
Academic Article
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Times cited: 105 -
Phase I study of XL281 (BMS-908662), a potent oral RAF kinase inhibitor, in patients with advanced solid tumors.
Investigational new drugs.
2014
Academic Article
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Times cited: 17 -
Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment.
Human pathology.
2014
Academic Article
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Times cited: 242 -
Systemic treatment options for radiation-associated sarcomas.
Current treatment options in oncology.
2014
Information Resource
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Times cited: 4 -
Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.
JAMA.
2014
Academic Article
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Times cited: 361 -
Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells.
Leukemia research reports.
2014
Academic Article
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Times cited: 17 -
Myasthenia Gravis Induced by Ipilimumab in Patients With Metastatic Melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2014
Academic Article
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Times cited: 92 -
High-risk features in radiation-associated breast angiosarcomas.
British journal of cancer.
2013
Academic Article
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Times cited: 58 -
Ipilimumab for patients with advanced mucosal melanoma.
The oncologist.
2013
Academic Article
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Times cited: 134 -
Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2013
Academic Article
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Times cited: 360 -
Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.
The Lancet. Oncology.
2013
Academic Article
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Times cited: 176 -
Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors.
Annals of oncology : official journal of the European Society for Medical Oncology.
2012
Academic Article
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Times cited: 88 -
The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2012
Academic Article
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Times cited: 83 -
Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1).
British journal of cancer.
2011
Academic Article
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Times cited: 229 -
A phase I clinical trial of safingol in combination with cisplatin in advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2011
Academic Article
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Times cited: 131 -
A phase I pharmacokinetic study of pulse-dose vorinostat with flavopiridol in solid tumors.
Investigational new drugs.
2010
Academic Article
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Times cited: 33 -
A phase I clinical trial of FOLFIRI in combination with the pan-cyclin-dependent kinase (CDK) inhibitor flavopiridol.
Cancer chemotherapy and pharmacology.
2010
Academic Article
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Times cited: 25 -
Phase I study of flavopiridol with oxaliplatin and fluorouracil/leucovorin in advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 48 - Development of cell-cycle inhibitors for cancer therapy. Current oncology (Toronto, Ont.). 2009 Academic Article GET IT