selected publications
- ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer. Oncotarget. 2019 Academic Article GET IT
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Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.
Nature medicine.
2017
Academic Article
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Times cited: 290 -
A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.
Molecular systems biology.
2017
Academic Article
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Times cited: 35 -
Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine.
Cancer discovery.
2013
Academic Article
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Times cited: 40 -
A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.
Cell stem cell.
2013
Academic Article
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Times cited: 323 -
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
Experimental cell research.
2013
Academic Article
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Times cited: 40 -
Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
Journal of cellular physiology.
2013
Academic Article
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Times cited: 41 -
Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
Cancer research.
2009
Academic Article
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Times cited: 68 -
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
Human mutation.
2008
Academic Article
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Times cited: 92 -
Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.
Developmental dynamics : an official publication of the American Association of Anatomists.
2008
Academic Article
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Times cited: 61