selected publications
- Diet and Cancer Metabolism. Cold Spring Harbor perspectives in medicine. 2024 Academic Article GET IT
- A waste product's unexpected role in wasting. Nature metabolism. 2024 Academic Article GET IT
- Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique. NPJ breast cancer. 2024 Academic Article GET IT
- Epinephrine inhibits PI3Kα via the Hippo kinases. Cell reports. 2023 Academic Article GET IT
- Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant. Molecular metabolism. 2023 Academic Article GET IT
- Biological role of fructose in the male reproductive system: Potential implications for prostate cancer. The Prostate. 2023 Review GET IT
- TIMP1 is an early biomarker for detection and prognosis of lung cancer. Clinical and translational medicine. 2023 Academic Article GET IT
- Profiling of Skeletal Muscle and Adipose Tissue Depots in Men with Advanced Prostate Cancer Receiving Different Forms of Androgen Deprivation Therapy. European urology open science. 2023 Academic Article GET IT
- Sodium-glucose cotransporter-2 inhibitors for hypergycemia in phosphoinositide 3-kinase pathway inhibition. Breast cancer research and treatment. 2023 Academic Article GET IT
- The proteasome regulates body weight and systemic nutrient metabolism during fasting. American journal of physiology. Endocrinology and metabolism. 2023 Academic Article GET IT
- STX-478, a Mutant-Selective, Allosteric PI3Ka Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Ka-Mutant Xenografts. Cancer discovery. 2023 Academic Article GET IT
- Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. Cell metabolism. 2023 Academic Article GET IT
- Cachexia: A systemic consequence of progressive, unresolved disease. Cell. 2023 Review GET IT
- An atlas of substrate specificities for the human serine/threonine kinome. Nature. 2023 Academic Article GET IT
- Selective targeting of visceral adiposity by polycation nanomedicine. Nature nanotechnology. 2022 Academic Article GET IT
- PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes. Science immunology. 2022 Academic Article GET IT
- Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer. Nature communications. 2022 Academic Article GET IT
- Systemic Ketone Replacement Does Not Improve Survival or Cancer Cachexia in Mice With Lung Cancer. Frontiers in oncology. 2022 Academic Article GET IT
- Developing dietary interventions as therapy for cancer. Nature reviews. Cancer. 2022 Review GET IT
- Characterization, management, and risk factors of hyperglycemia during PI3K or AKT inhibitor treatment. Cancer medicine. 2022 Academic Article GET IT
- Diabetes Epidemiology Among Adults in Port-au-Prince, Haiti: A Cross-Sectional Study. Frontiers in endocrinology. 2022 Academic Article GET IT
- A multidisciplinary approach to optimizing care of patients treated with alpelisib. Breast (Edinburgh, Scotland). 2021 Review GET IT
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Dietary fructose improves intestinal cell survival and nutrient absorption.
Nature.
2021
Academic Article
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Times cited: 1 - GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase. Cancer & metabolism. 2021 Academic Article GET IT
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Engineered diets to improve cancer outcomes.
Current opinion in biotechnology.
2020
Information Resource
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Times cited: 2 - The effects of neoadjuvant chemotherapy and interval debulking surgery on body composition in patients with ovarian cancer. JCSM clinical reports. 2020 Academic Article GET IT
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A machine learning and network framework to discover new indications for small molecules.
PLoS computational biology.
2020
Academic Article
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Times cited: 9 -
Insulin-PI3K signalling: an evolutionarily insulated metabolic driver of cancer.
Nature reviews. Endocrinology.
2020
Information Resource
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Times cited: 149 -
High-fructose corn syrup enhances intestinal tumor growth in mice.
Science (New York, N.Y.).
2019
Academic Article
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Times cited: 216 -
Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer.
Cancers.
2019
Academic Article
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Times cited: 42 -
Optimal Management of Adverse Events From Copanlisib in the Treatment of Patients With Non-Hodgkin Lymphomas.
Clinical lymphoma, myeloma & leukemia.
2018
Academic Article
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Times cited: 36 -
Computed tomography-derived assessments of regional muscle volume: Validating their use as predictors of whole body muscle volume in cancer patients.
The British journal of radiology.
2018
Academic Article
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Times cited: 10 -
Suppression of insulin feedback enhances the efficacy of PI3K inhibitors.
Nature.
2018
Academic Article
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Times cited: 412 -
Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Molecular cell.
2018
Academic Article
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Times cited: 61 -
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
Proceedings of the National Academy of Sciences of the United States of America.
2018
Academic Article
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Times cited: 76 -
Imaging skeletal muscle volume, density, and FDG uptake before and after induction therapy for non-small cell lung cancer.
Clinical radiology.
2018
Academic Article
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Times cited: 11 -
Regional Variation in Skeletal Muscle and Adipose Tissue FDG Uptake Using PET/CT and Their Relation to BMI.
Academic radiology.
2017
Academic Article
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Times cited: 10 -
Obesity and Cancer Mechanisms: Cancer Metabolism.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Information Resource
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Times cited: 226 -
A Study of the Feasibility of FDG-PET/CT to Systematically Detect and Quantify Differential Metabolic Effects of Chronic Tobacco Use in Organs of the Whole Body-A Prospective Pilot Study.
Academic radiology.
2016
Academic Article
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Times cited: 8 -
FDG-PET/CT assessment of differential chemotherapy effects upon skeletal muscle metabolism in patients with melanoma.
Annals of nuclear medicine.
2014
Academic Article
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Times cited: 3 -
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Science (New York, N.Y.).
2012
Academic Article
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Times cited: 959 -
Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy.
The American journal of pathology.
2011
Academic Article
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Times cited: 83 -
Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition.
PloS one.
2010
Academic Article
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Times cited: 49 -
The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity.
International journal of obesity (2005).
2009
Academic Article
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Times cited: 108 -
The treatment of night eating: the patient's perspective.
European eating disorders review : the journal of the Eating Disorders Association.
2009
Academic Article
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Times cited: 13 -
Oscillatory phosphorylation of yeast Fus3 MAP kinase controls periodic gene expression and morphogenesis.
Current biology : CB.
2008
Academic Article
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Times cited: 55