selected publications
- The neutrophil to lymphocyte ratio associates with markers of Alzheimer's disease pathology in cognitively unimpaired elderly people. Immunity & ageing : I & A. 2024 Academic Article GET IT
- Evidence of Pericyte Damage in a Cognitively Normal Cohort: Association With CSF and PET Biomarkers of Alzheimer's Disease. Alzheimer disease and associated disorders. 2024 Academic Article GET IT
- DeepFDR: A Deep Learning-based False Discovery Rate Control Method for Neuroimaging Data. Proceedings of machine learning research. 2024 Academic Article GET IT
- Reduction in Constitutively Activated Auditory Brainstem Microglia in Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024 Academic Article GET IT
- Brain Fluid Clearance After Traumatic Brain Injury Measured Using Dynamic Positron Emission Tomography. Neurotrauma reports. 2024 Academic Article GET IT
- [1-11C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjects. Fluids and barriers of the CNS. 2024 Academic Article GET IT
- Remote Associations Between Tau and Cortical Amyloid-β Are Stage-Dependent. Journal of Alzheimer's disease : JAD. 2024 Academic Article GET IT
- Quantitative transport mapping of multi-delay arterial spin labeling MRI detects early blood perfusion alteration in Alzheimer's disease. 2024 GET IT
- Diffusion Tensor Imaging Along Perivascular Spaces (DTI-ALPS) to Assess Effects of Age, Sex, and Head Size on Interstitial Fluid Dynamics in Healthy Subjects. Journal of Alzheimer's disease reports. 2024 Academic Article GET IT
- Impaired sleep is associated with tau deposition on 18F-flortaucipir PET and accelerated cognitive decline, accounting for medications that affect sleep. Journal of the neurological sciences. 2024 Academic Article GET IT
- Parenchymal CSF fraction is a measure of brain glymphatic clearance and positively associated with amyloid beta deposition on PET. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Academic Article GET IT
- Cerebral Amyloid Angiopathy and Risk of Isolated Nontraumatic Subdural Hemorrhage. JAMA neurology. 2024 Academic Article GET IT
- Multimodal Assessment of Brain Fluid Clearance is Associated with Amyloid-Beta Deposition in Humans. Journal of neuroradiology = Journal de neuroradiologie. 2023 Academic Article GET IT
- Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Review GET IT
- Thriving In and Out of the Reading Room: A Faculty Development Workshop. Academic radiology. 2023 Academic Article GET IT
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Association of brain tissue cerebrospinal fluid fraction with age in healthy cognitively normal adults.
Frontiers in aging neuroscience.
2023
Academic Article
GET IT
Times cited: 5 - Peripheral immune cell imbalance is associated with cortical beta-amyloid deposition and longitudinal cognitive decline. Scientific reports. 2023 Academic Article GET IT
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Brain fog in long COVID limits function and health status, independently of hospital severity and preexisting conditions.
Frontiers in neurology.
2023
Academic Article
GET IT
Times cited: 7 - Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome. Journal of magnetic resonance imaging : JMRI. 2023 Review GET IT
- Glymphatic clearance estimated using diffusion tensor imaging along perivascular spaces is reduced after traumatic brain injury and correlates with plasma neurofilament light, a biomarker of injury severity. Brain communications. 2023 Academic Article GET IT
- A conformal TOF-DOI Prism-PET prototype scanner For high resolution quantitative neuroimaging. Medical physics. 2023 Academic Article GET IT
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Tau PET following acute TBI: Off-target binding to blood products, tauopathy, or both?.
Frontiers in neuroimaging.
2022
Academic Article
GET IT
Times cited: 104 - Quadratic relationship between systolic blood pressure and white matter lesions in individuals with hypertension. Journal of hypertension. 2022 Academic Article GET IT
- Association of liver fibrosis with cognitive test performance and brain imaging parameters in the UK Biobank study. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022 Academic Article GET IT
- Higher body mass index is associated with worse hippocampal vasoreactivity to carbon dioxide. Frontiers in aging neuroscience. 2022 Academic Article GET IT
- Positron Emission Tomography reveals age-associated hypothalamic microglial activation in women. Scientific reports. 2022 Academic Article GET IT
- Association between Liver Fibrosis and Incident Dementia in the UK Biobank Study. European journal of neurology. 2022 Academic Article GET IT
- Quantifying cerebrospinal fluid dynamics: A review of human neuroimaging contributions to CSF physiology and neurodegenerative disease. Neurobiology of disease. 2022 Review GET IT
- Association between lower body temperature and increased tau pathology in cognitively normal older adults. Neurobiology of disease. 2022 Academic Article GET IT
- Statistical Parametric Mapping in Amyloid Positron Emission Tomography. Frontiers in aging neuroscience. 2022 Academic Article GET IT
- Quantitative Water Permeability Mapping of Blood-Brain-Barrier Dysfunction in Aging. Frontiers in aging neuroscience. 2022 Academic Article GET IT
- Brain oxygen extraction and neural tissue susceptibility are associated with cognitive impairment in older individuals. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2022 Academic Article GET IT
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Decreased CSF clearance and increased brain amyloid in Alzheimer's disease.
Fluids and barriers of the CNS.
2022
Academic Article
GET IT
Times cited: 44 - Association Between Systemic Amyloidosis and Intracranial Hemorrhage. Stroke. 2022 Letter GET IT
- Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA neurology. 2022 Academic Article GET IT
- Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome. Acta neuropathologica communications. 2022 Academic Article GET IT
- The Brain-Nose Interface: A Potential Cerebrospinal Fluid Clearance Site in Humans. Frontiers in physiology. 2022 Review GET IT
- Interactive Associations of Neuropsychiatry Inventory-Questionnaire Assessed Sleep Disturbance and Vascular Risk on Alzheimer's Disease Stage Progression in Clinically Normal Older Adults. Frontiers in aging neuroscience. 2021 Academic Article GET IT
- Microglial activation and tau propagate jointly across Braak stages. Nature medicine. 2021 Academic Article GET IT
- Obesity and Race May Explain Differential Burden of White Matter Hyperintensity Load. Clinical interventions in aging. 2021 Academic Article GET IT
- Heuristic scoring method utilizing FDG-PET statistical parametric mapping in the evaluation of suspected Alzheimer disease and frontotemporal lobar degeneration. American journal of nuclear medicine and molecular imaging. 2021 Academic Article GET IT
- Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus Cholinesterase Inhibition to reduce Neurologic Decline in Alzheimer's. Contemporary clinical trials. 2021 Academic Article GET IT
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Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition.
Scientific reports.
2021
Academic Article
GET IT
Times cited: 91 -
Diffusion tensor-based analysis of white matter in the healthy aging canine brain.
Neurobiology of aging.
2021
Academic Article
GET IT
Times cited: 1 -
Periodontal dysbiosis associates with reduced CSF Aβ42 in cognitively normal elderly.
Alzheimer's & dementia (Amsterdam, Netherlands).
2021
Academic Article
GET IT
Times cited: 28 - Betahydroxybutyrate Consumption in Autopsy Brain Tissue from Alzheimer's Disease Subjects. Journal of Alzheimer's disease reports. 2021 Academic Article GET IT
- Cognitive dysfunction in young subjects with periodontal disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2021 Academic Article GET IT
- Clinicopathological Staging of Dynamics of Neurodegeneration and Neuronal Loss in Alzheimer Disease. Journal of neuropathology and experimental neurology. 2021 Academic Article GET IT
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Self-reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer's disease time-dependent progression.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2020
Academic Article
GET IT
Times cited: 26 -
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy.
Alzheimer's & dementia (Amsterdam, Netherlands).
2020
Academic Article
GET IT
Times cited: 72 -
Sex-driven modifiers of Alzheimer risk: A multimodality brain imaging study.
Neurology.
2020
Academic Article
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Times cited: 89 -
Periodontal disease as a possible cause for Alzheimer's disease.
Periodontology 2000.
2020
Information Resource
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Times cited: 15 - Synthesis of [1-11C]Butanol via a facile solid phase extraction protocol. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2020 Academic Article GET IT
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Non-coding variability at the APOE locus contributes to the Alzheimer's risk.
Nature communications.
2019
Academic Article
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Times cited: 84 -
Plasma tau complements CSF tau and P-tau in the diagnosis of Alzheimer's disease.
Alzheimer's & dementia (Amsterdam, Netherlands).
2019
Academic Article
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Times cited: 99 -
A blood-based signature of cerebrospinal fluid Aβ1-42 status.
Scientific reports.
2019
Academic Article
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Times cited: 23 -
Sleep oscillation-specific associations with Alzheimer's disease CSF biomarkers: novel roles for sleep spindles and tau.
Molecular neurodegeneration.
2019
Academic Article
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Times cited: 59 -
Predicting Alzheimer's disease progression using multi-modal deep learning approach.
Scientific reports.
2019
Academic Article
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Times cited: 288 -
Precisely-Measured Hydration Status Correlates with Hippocampal Volume in Healthy Older Adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.
2019
Article
GET IT
Times cited: 3 -
Different Relationship Between Systolic Blood Pressure and Cerebral Perfusion in Subjects With and Without Hypertension.
Hypertension (Dallas, Tex. : 1979).
2019
Academic Article
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Times cited: 41 -
Two Year Outcomes, Cognitive and Behavioral Markers of Decline in Healthy, Cognitively Normal Older Persons with Global Deterioration Scale Stage 2 (Subjective Cognitive Decline with Impairment).
Journal of Alzheimer's disease : JAD.
2019
Academic Article
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Times cited: 4 -
Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging study.
PloS one.
2018
Academic Article
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Times cited: 127 -
Associations of lifestyle and vascular risk factors with Alzheimer's brain biomarker changes during middle age: a 3-year longitudinal study in the broader New York City area.
BMJ open.
2018
Academic Article
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Times cited: 31 -
Military-related risk factors for dementia.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2018
Review
GET IT
Times cited: 19 -
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.
Nature communications.
2018
Academic Article
GET IT
Times cited: 291 -
Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study.
The Lancet. Neurology.
2018
Academic Article
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Times cited: 78 -
Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity.
Aging cell.
2018
Academic Article
GET IT
Times cited: 57 -
Quantitative evaluation of tau PET tracers 18F-THK5351 and 18F-AV-1451 in Alzheimer's disease with standardized uptake value peak-alignment (SUVP) normalization.
European journal of nuclear medicine and molecular imaging.
2018
Academic Article
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Times cited: 16 -
Challenges associated with biomarker-based classification systems for Alzheimer's disease.
Alzheimer's & dementia (Amsterdam, Netherlands).
2018
Academic Article
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Times cited: 47 -
Mediterranean diet and 3-year Alzheimer brain biomarker changes in middle-aged adults.
Neurology.
2018
Academic Article
GET IT
Times cited: 128 -
Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images.
Scientific reports.
2018
Academic Article
GET IT
Times cited: 286 -
Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly. A Longitudinal Study.
American journal of respiratory and critical care medicine.
2018
Academic Article
GET IT
Times cited: 180 -
Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2018
Academic Article
GET IT
Times cited: 33 -
Lifestyle and vascular risk effects on MRI-based biomarkers of Alzheimer's disease: a cross-sectional study of middle-aged adults from the broader New York City area.
BMJ open.
2018
Academic Article
GET IT
Times cited: 64 - Reply: Cerebrospinal Fluid, Hyposmia, and Dementia in Alzheimer Disease: Insights from Dynamic PET and a Hypothesis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Article GET IT
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The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer's disease.
PloS one.
2018
Academic Article
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Times cited: 43 -
Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease.
Neurobiology of aging.
2018
Academic Article
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Times cited: 27 -
Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link.
EBioMedicine.
2018
Information Resource
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Times cited: 256 -
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.
JAMA psychiatry.
2018
Academic Article
GET IT
Times cited: 119 -
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.
2017
Information Resource
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Times cited: 200 -
Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery.
PloS one.
2017
Academic Article
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Times cited: 103 -
Sex differences in Alzheimer risk: Brain imaging of endocrine vs chronologic aging.
Neurology.
2017
Academic Article
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Times cited: 184 -
Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features.
Scientific reports.
2017
Academic Article
GET IT
Times cited: 13 - Multiregional Age-Associated Reduction of Brain Neuronal Reserve Without Association With Neurofibrillary Degeneration or β-Amyloidosis. Journal of neuropathology and experimental neurology. 2017 Academic Article GET IT
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Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2017
Academic Article
GET IT
Times cited: 159 -
Relationship between Clinical Parameters and Brain Structure in Sporadic Amyotrophic Lateral Sclerosis Patients According to Onset Type: A Voxel-Based Morphometric Study.
PloS one.
2017
Academic Article
GET IT
Times cited: 21 -
Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly.
Sleep.
2016
Academic Article
GET IT
Times cited: 139 - The Alzheimer's Imaging Consortium: Celebrating 20Â years of creativity and progress. Alzheimer's & dementia (Amsterdam, Netherlands). 2016 Editorial Article GET IT
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Structural explanation of poor prognosis of amyotrophic lateral sclerosis in the non-demented state.
European journal of neurology.
2016
Academic Article
GET IT
Times cited: 10 - Peri-Operative Inflammatory Cytokines in Plasma of the Elderly Correlate in Prospective Study with Postoperative Changes in Cognitive Test Scores. International journal of anesthesiology & research. 2016 Academic Article GET IT
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Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects.
Sleep.
2016
Academic Article
GET IT
Times cited: 42 -
Effects of vascular risk factors, statins, and antihypertensive drugs on PiB deposition in cognitively normal subjects.
Alzheimer's & dementia (Amsterdam, Netherlands).
2016
Academic Article
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Times cited: 28 -
Brain Atrophy of Secondary REM-Sleep Behavior Disorder in Neurodegenerative Disease.
Journal of Alzheimer's disease : JAD.
2016
Academic Article
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Times cited: 26 -
Periodontal disease's contribution to Alzheimer's disease progression in Down syndrome.
Alzheimer's & dementia (Amsterdam, Netherlands).
2016
Information Resource
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Times cited: 35 -
Greater specificity for cerebrospinal fluid P-tau231 over P-tau181 in the differentiation of healthy controls from Alzheimer's disease.
Journal of Alzheimer's disease : JAD.
2016
Academic Article
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Times cited: 34 -
APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls.
Oncotarget.
2015
Academic Article
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Times cited: 96 -
Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects.
Brain : a journal of neurology.
2015
Academic Article
GET IT
Times cited: 105 -
Clearance systems in the brain-implications for Alzheimer disease.
Nature reviews. Neurology.
2015
Information Resource
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Times cited: 1113 -
Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE.
Nature communications.
2015
Academic Article
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Times cited: 245 -
Comparison of the Brain Volume in Essential Tremor and Parkinson's Disease Tremor Using an Automated Segmentation Method.
European neurology.
2015
Academic Article
GET IT
Times cited: 12 -
Sleep-disordered breathing advances cognitive decline in the elderly.
Neurology.
2015
Academic Article
GET IT
Times cited: 325 -
Nutrient patterns and brain biomarkers of Alzheimer's disease in cognitively normal individuals.
The journal of nutrition, health & aging.
2015
Academic Article
GET IT
Times cited: 122 -
Relationship between hippocampal atrophy and neuropathology markers: a 7T MRI validation study of the EADC-ADNI Harmonized Hippocampal Segmentation Protocol.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2015
Academic Article
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Times cited: 63 -
Cortical laminar binding of PET amyloid and tau tracers in Alzheimer disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2015
Academic Article
GET IT
Times cited: 21 -
Periodontal disease associates with higher brain amyloid load in normal elderly.
Neurobiology of aging.
2014
Academic Article
GET IT
Times cited: 194 -
Reduced retention of Pittsburgh compound B in white matter lesions.
European journal of nuclear medicine and molecular imaging.
2014
Academic Article
GET IT
Times cited: 27 - Physical Activity, Mediterranean Diet and Biomarkers-Assessed Risk of Alzheimer's: A Multi-Modality Brain Imaging Study. Advances in molecular imaging. 2014 Academic Article GET IT
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The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2014
Academic Article
GET IT
Times cited: 157 -
Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter.
NeuroImage.
2014
Academic Article
GET IT
Times cited: 22 -
Nutrient intake and brain biomarkers of Alzheimer's disease in at-risk cognitively normal individuals: a cross-sectional neuroimaging pilot study.
BMJ open.
2014
Academic Article
GET IT
Times cited: 70 - Mediterranean Diet and Magnetic Resonance Imaging-Assessed Brain Atrophy in Cognitively Normal Individuals at Risk for Alzheimer's Disease. The journal of prevention of Alzheimer's disease. 2014 Academic Article GET IT
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Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2014
Information Resource
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Times cited: 364 -
Comparison of human septal nuclei MRI measurements using automated segmentation and a new manual protocol based on histology.
NeuroImage.
2014
Academic Article
GET IT
Times cited: 25 - The cerebrospinal fluid "Alzheimer profile": easily said, but what does it mean?. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2014 Academic Article GET IT
- FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease. Advances in molecular imaging. 2014 Academic Article GET IT
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Brain imaging of cognitively normal individuals with 2 parents affected by late-onset AD.
Neurology.
2014
Academic Article
GET IT
Times cited: 49 -
Interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals.
Neurobiology of aging.
2013
Academic Article
GET IT
Times cited: 107 -
Imaging and cerebrospinal fluid biomarkers in the search for Alzheimer's disease mechanisms.
Neuro-degenerative diseases.
2013
Academic Article
GET IT
Times cited: 12 -
Blood pressure decrease correlates with tau pathology and memory decline in hypertensive elderly.
Neurobiology of aging.
2013
Academic Article
GET IT
Times cited: 64 -
Imaging markers for Alzheimer disease: which vs how.
Neurology.
2013
Information Resource
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Times cited: 198 -
Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2013
Academic Article
GET IT
Times cited: 37 - Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease. JAMA neurology. 2013 Academic Article GET IT
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Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer's disease transgenic mice using magnetic resonance microimaging.
PloS one.
2013
Academic Article
GET IT
Times cited: 96 -
Inge Grundke-Iqbal, Ph.D. (1937–2012): the discoverer of the abnormal hyperphosphorylation of tau in Alzheimer’s disease.
Journal of molecular neuroscience : MN.
2013
Academic Article
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Times cited: 2 -
Cerebrovascular reactivity to carbon dioxide in Alzheimer's disease.
Journal of Alzheimer's disease : JAD.
2013
Information Resource
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Times cited: 103 -
Alternative normalization methods demonstrate widespread cortical hypometabolism in untreated de novo Parkinson's disease.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....
2012
Academic Article
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Times cited: 15 -
Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders.
PloS one.
2012
Academic Article
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Times cited: 51 -
Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents.
Neurobiology of aging.
2012
Academic Article
GET IT
Times cited: 52 -
Surgery and brain atrophy in cognitively normal elderly subjects and subjects diagnosed with mild cognitive impairment.
Anesthesiology.
2012
Academic Article
GET IT
Times cited: 86 -
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 46 -
Age and diagnostic performance of Alzheimer disease CSF biomarkers.
Neurology.
2012
Academic Article
GET IT
Times cited: 147 -
The concept of FDG-PET endophenotype in Alzheimer's disease.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2011
Information Resource
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Times cited: 11 -
Alzheimer's disease markers, hypertension, and gray matter damage in normal elderly.
Neurobiology of aging.
2011
Academic Article
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Times cited: 60 -
Maternal age affects brain metabolism in adult children of mothers affected by Alzheimer's disease.
Neurobiology of aging.
2011
Academic Article
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Times cited: 9 -
Midbrain atrophy in vascular Parkinsonism.
European neurology.
2011
Academic Article
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Times cited: 20 -
Resting-state glucose metabolism level is associated with the regional pattern of amyloid pathology in Alzheimer's disease.
International journal of Alzheimer's disease.
2011
Academic Article
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Times cited: 13 -
Greater risk of Alzheimer's disease in older adults with insomnia.
Journal of the American Geriatrics Society.
2011
Article
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Times cited: 149 -
Structural brain changes in normal individuals with a maternal history of Alzheimer's.
Neurobiology of aging.
2011
Academic Article
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Times cited: 50 -
Detection of amyloid plaques targeted by USPIO-Aβ1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging.
NeuroImage.
2011
Academic Article
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Times cited: 131 -
Hippocampal blood flow in normal aging measured with arterial spin labeling at 3T.
Magnetic resonance in medicine.
2011
Academic Article
GET IT
Times cited: 28 -
Link between DYRK1A overexpression and several-fold enhancement of neurofibrillary degeneration with 3-repeat tau protein in Down syndrome.
Journal of neuropathology and experimental neurology.
2011
Academic Article
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Times cited: 65 -
Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimer's disease.
Journal of Alzheimer's disease : JAD.
2011
Academic Article
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Times cited: 79 -
Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol.
Journal of Alzheimer's disease : JAD.
2011
Academic Article
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Times cited: 121 -
Oxidative stress and amyloid-beta pathology in normal individuals with a maternal history of Alzheimer's.
Biological psychiatry.
2010
Academic Article
GET IT
Times cited: 42 -
Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2010
Academic Article
GET IT
Times cited: 60 -
Does mild cognitive impairment increase the risk of developing postoperative cognitive dysfunction?.
American journal of surgery.
2010
Academic Article
GET IT
Times cited: 73 -
Evaluation of Early Dementia (Mild Cognitive Impairment).
PET clinics.
2010
Information Resource
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Times cited: 4 -
Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's.
Proceedings of the National Academy of Sciences of the United States of America.
2010
Academic Article
GET IT
Times cited: 120 -
The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes.
Acta neuropathologica.
2010
Academic Article
GET IT
Times cited: 458 -
Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative.
NeuroImage.
2010
Academic Article
GET IT
Times cited: 135 -
Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders.
Neurobiology of aging.
2010
Academic Article
GET IT
Times cited: 38 -
Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes.
Human genomics.
2010
Information Resource
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Times cited: 76 -
Pre-clinical detection of Alzheimer's disease using FDG-PET, with or without amyloid imaging.
Journal of Alzheimer's disease : JAD.
2010
Information Resource
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Times cited: 226 -
TNF-alpha and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects.
Journal of neuroimmunology.
2009
Academic Article
GET IT
Times cited: 233 -
CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.
JAMA.
2009
Academic Article
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Times cited: 829 -
An entorhinal cortex sulcal pattern is associated with Alzheimer's disease.
Human brain mapping.
2009
Academic Article
GET IT
Times cited: 13 -
FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease.
European journal of nuclear medicine and molecular imaging.
2009
Academic Article
GET IT
Times cited: 380 -
Effects of memantine on cerebrospinal fluid biomarkers of neurofibrillary pathology.
Journal of Alzheimer's disease : JAD.
2009
Academic Article
GET IT
Times cited: 7 -
Magnetic resonance imaging improves cerebrospinal fluid biomarkers in the early detection of Alzheimer's disease.
Journal of Alzheimer's disease : JAD.
2009
Academic Article
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Times cited: 55 -
Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease.
Neurology.
2008
Academic Article
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Times cited: 160 -
Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal.
Neurobiology of aging.
2008
Academic Article
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Times cited: 252 -
Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer's disease.
Biological psychiatry.
2008
Academic Article
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Times cited: 306 -
Anteroposterior hippocampal metabolic heterogeneity: three-dimensional multivoxel proton 1H MR spectroscopic imaging--initial findings.
Radiology.
2008
Academic Article
GET IT
Times cited: 21 -
Robust and conventional neuropsychological norms: diagnosis and prediction of age-related cognitive decline.
Neuropsychology.
2008
Academic Article
GET IT
Times cited: 69 - Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease. European journal of nuclear medicine and molecular imaging. 2008 Academic Article GET IT
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Alzheimer's disease and peripheral infections: the possible contribution from periodontal infections, model and hypothesis.
Journal of Alzheimer's disease : JAD.
2008
Information Resource
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Times cited: 108 -
Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2008
Academic Article
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Times cited: 583 -
Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study.
Progress in neuro-psychopharmacology & biological psychiatry.
2008
Academic Article
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Times cited: 23 -
Longitudinal CSF isoprostane and MRI atrophy in the progression to AD.
Journal of neurology.
2007
Academic Article
GET IT
Times cited: 73 -
Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism.
Proceedings of the National Academy of Sciences of the United States of America.
2007
Academic Article
GET IT
Times cited: 206 -
The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease.
Neurobiology of aging.
2007
Academic Article
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Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment.
Neurobiology of aging.
2007
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Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein E E4 carriers with subjective memory complaints.
Biological psychiatry.
2007
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Subjective memory complaints: presence, severity and future outcome in normal older subjects.
Dementia and geriatric cognitive disorders.
2007
Academic Article
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(18)F-FDG PET database of longitudinally confirmed healthy elderly individuals improves detection of mild cognitive impairment and Alzheimer's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2007
Academic Article
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Quantitation, regional vulnerability, and kinetic modeling of brain glucose metabolism in mild Alzheimer's disease.
European journal of nuclear medicine and molecular imaging.
2007
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Times cited: 38 -
Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease.
Neurology.
2007
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Prefrontal N-acetylaspartate and poststroke recovery: a longitudinal proton spectroscopy study.
AJNR. American journal of neuroradiology.
2007
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A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice.
Neurobiology of aging.
2007
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Seeing what Alzheimer saw.
Nature medicine.
2007
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Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration.
Acta neuropathologica.
2007
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Hippocampal hypometabolism predicts cognitive decline from normal aging.
Neurobiology of aging.
2007
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Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2006
Academic Article
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Alzheimer's disease.
Lancet (London, England).
2006
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Mild cognitive impairment.
Lancet (London, England).
2006
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Hippocampal cerebrospinal fluid spaces on MR imaging: Relationship to aging and Alzheimer disease.
AJNR. American journal of neuroradiology.
2006
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Biomarkers for the early diagnosis of Alzheimer's disease.
The Lancet. Neurology.
2006
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Visual rating of medial temporal lobe metabolism in mild cognitive impairment and Alzheimer's disease using FDG-PET.
European journal of nuclear medicine and molecular imaging.
2005
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Subjective memory complaints in aging are associated with elevated cortisol levels.
Neurobiology of aging.
2005
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The role of quantitative structural imaging in the early diagnosis of Alzheimer's disease.
Neuroimaging clinics of North America.
2005
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Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment.
Neurobiology of aging.
2005
Academic Article
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Reduced hippocampal metabolism in MCI and AD: automated FDG-PET image analysis.
Neurology.
2005
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Absence of hippocampal volume differences in survivors of the Nazi Holocaust with and without posttraumatic stress disorder.
Psychiatry research.
2005
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Atrophy rate in medial temporal lobe during progression of Alzheimer disease.
Neurology.
2004
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Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease.
Neurobiology of aging.
2004
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Magnetic resonance and PET studies in the early diagnosis of Alzheimer's disease.
Expert review of neurotherapeutics.
2004
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Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment.
Journal of internal medicine.
2004
Conference Paper
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Cell type- and brain structure-specific patterns of distribution of minibrain kinase in human brain.
Brain research.
2004
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MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease.
Magnetic resonance in medicine.
2004
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Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging.
Radiology.
2003
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Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly.
Proceedings of the National Academy of Sciences of the United States of America.
2003
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Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment.
Neuroscience letters.
2002
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Salivary cortisol day profiles in elderly with mild cognitive impairment.
Psychoneuroendocrinology.
2002
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Volumetric measurement of the hippocampus, the anterior cingulate cortex, and the retrosplenial granular cortex of the rat using structural MRI.
Brain research. Brain research protocols.
2002
Academic Article
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Volumetric structural magnetic resonance imaging (MRI) of the rat hippocampus following kainic acid (KA) treatment.
Brain research.
2002
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Basal hypothalamo-pituitary-adrenal axis activity and corticotropin feedback in young and older men: relationships to magnetic resonance imaging-derived hippocampus and cingulate gyrus volumes.
Neuroendocrinology.
2002
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Changes in brain functional homogeneity in subjects with Alzheimer's disease.
Psychiatry research.
2002
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Hippocampal atrophy disrupts transfer generalization in nondemented elderly.
Journal of geriatric psychiatry and neurology.
2002
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Vascular fibrosis and calcification in the hippocampus in aging, Alzheimer disease, and Down syndrome.
Acta neuropathologica.
2001
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Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome.
JAMA.
2001
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Cortisol differentially affects memory in young and elderly men.
Behavioral neuroscience.
2001
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Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET).
Proceedings of the National Academy of Sciences of the United States of America.
2001
Academic Article
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Hippocampal formation glucose metabolism and volume losses in MCI and AD.
Neurobiology of aging.
2001
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Fibrillar amyloid-beta affects neurofibrillary changes but only in neurons already involved in neurofibrillary degeneration.
Acta neuropathologica.
2001
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Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD.
Neurology.
2001
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Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease.
Neurobiology of aging.
2000
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The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease.
Neuroscience.
2000
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MRI volume of the amygdala: a reliable method allowing separation from the hippocampal formation.
Psychiatry research.
1999
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Cerebellar atrophy in Alzheimer's disease-clinicopathological correlations.
Brain research.
1999
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Neuronal and volume loss in CA1 of the hippocampal formation uniquely predicts duration and severity of Alzheimer disease.
Brain research.
1998
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Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease.
Annals of neurology.
1998
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Duration of neurofibrillary changes in the hippocampal pyramidal neurons.
Brain research.
1998
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Cortisol levels during human aging predict hippocampal atrophy and memory deficits.
Nature neuroscience.
1998
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MR differential diagnosis of normal-pressure hydrocephalus and Alzheimer disease: significance of perihippocampal fissures.
AJNR. American journal of neuroradiology.
1998
Academic Article
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Cortisol reduces hippocampal glucose metabolism in normal elderly, but not in Alzheimer's disease.
The Journal of clinical endocrinology and metabolism.
1997
Academic Article
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Hippocampal atrophy as detected by width of the temporal horn is greater in Alzheimer dementia than in nondementing cognitive impairment.
AJNR. American journal of neuroradiology.
1997
Article
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Relationships between regional neuronal loss and neurofibrillary changes in the hippocampal formation and duration and severity of Alzheimer disease.
Journal of neuropathology and experimental neurology.
1997
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Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease.
Neurobiology of aging.
1997
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Contribution of structural neuroimaging to the early diagnosis of Alzheimer's disease.
International psychogeriatrics.
1997
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Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease.
Neurobiology of aging.
1997
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Neurofibrillary pathology--correlation with hippocampal formation atrophy in Alzheimer disease.
Neurobiology of aging.
1996
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Hippocampal formation size predicts declining memory performance in normal aging.
Neurology.
1996
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Atrophy of hippocampal formation subdivisions correlates with stage and duration of Alzheimer disease.
Dementia (Basel, Switzerland).
1995
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Hippocampal atrophy and cognitive impairment.
Lancet (London, England).
1995
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Nonspecific leukoencephalopathy associated with aging.
Neuroimaging clinics of North America.
1995
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The differential diagnosis of Alzheimer's disease. Cerebral atrophy versus normal pressure hydrocephalus.
Neuroimaging clinics of North America.
1995
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Times cited: 24 -
The hippocampus in aging and Alzheimer's disease.
Neuroimaging clinics of North America.
1995
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Hippocampal volume losses in minimally impaired elderly.
Lancet (London, England).
1995
Article
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Age-related changes in brain: I. Magnetic resonance imaging measures of temporal lobe volumes in normal subjects.
The Psychiatric quarterly.
1995
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Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects.
The Psychiatric quarterly.
1995
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Hippocampal atrophy correlates with severe cognitive impairment in elderly patients with suspected normal pressure hydrocephalus.
Journal of neurology, neurosurgery, and psychiatry.
1994
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Hippocampal formation size in normal human aging: a correlate of delayed secondary memory performance.
Learning & memory (Cold Spring Harbor, N.Y.).
1994
Academic Article
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Principal axes and surface fitting methods for three-dimensional image registration.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1993
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Hippocampal atrophy in normal aging. An association with recent memory impairment.
Archives of neurology.
1993
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The radiologic prediction of Alzheimer disease: the atrophic hippocampal formation.
AJNR. American journal of neuroradiology.
1993
Academic Article
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Measurement of medial temporal lobe atrophy in diagnosis of Alzheimer's disease.
Lancet (London, England).
1993
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Dilatation of the lateral part of the transverse fissure of the brain in Alzheimer's disease.
Acta neurobiologiae experimentalis.
1993
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Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation.
The Psychiatric quarterly.
1993
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Topography of cross-sectional and longitudinal glucose metabolic deficits in Alzheimer's disease. Pathophysiologic implications.
Archives of neurology.
1992
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CT diagnostic features of choroidal/hippocampal fissure complex in Alzheimer disease and progressive supranuclear palsy.
AJNR. American journal of neuroradiology.
1991
Article
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Alzheimer disease: measuring loss of cerebral gray matter with MR imaging.
Radiology.
1991
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Computed tomography scans and negative symptoms in schizophrenia: chronic schizophrenics with negative symptoms and nonenlarged lateral ventricles.
Acta psychiatrica Scandinavica.
1990
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CT diagnostic features of Alzheimer disease: importance of the choroidal/hippocampal fissure complex.
AJNR. American journal of neuroradiology.
1990
Academic Article
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Early marker for Alzheimer's disease: the atrophic hippocampus.
Lancet (London, England).
1989
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PET-deoxyglucose, CT, and neuropathology of age-related white matter pathology in normals and Alzheimer's patients.
Psychiatry research.
1989
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Altered glucose metabolism in microvessels from patients with Alzheimer's disease.
Annals of neurology.
1989
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Alzheimer's disease: longitudinal CT studies of ventricular change.
AJR. American journal of roentgenology.
1989
Academic Article
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Expression of growth-associated proteins (GAPs) in injured sensory axons of frogs acclimatized to 15 °C and 25 °C.
Restorative neurology and neuroscience.
1989
Academic Article
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The stage specific temporal course of Alzheimer's disease: functional and behavioral concomitants based upon cross-sectional and longitudinal observation.
Progress in clinical and biological research.
1989
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Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy.
Lancet (London, England).
1988
Article
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Significance of age-related white matter lesions.
Stroke.
1988
Article
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Elevated cerebellar glucose metabolism in microvascular white matter disease: normal aging and Alzheimer's disease.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
1988
Academic Article
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Longitudinal CT study of parenchymal brain changes in glioma survivors.
AJNR. American journal of neuroradiology.
1988
Academic Article
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Altered patterns of positron-emission tomography glucose metabolism in Alzheimer patients with microvascular white matter disease.
American journal of physiologic imaging.
1988
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Global Deterioration Scale (GDS).
Psychopharmacology bulletin.
1988
Academic Article
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Positron emission tomography with the deoxyglucose technique and the diagnosis of Alzheimer's disease.
Neurobiology of aging.
1988
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Positron emission tomography studies of normal aging: a replication of PET III and 18-FDG using PET VI and 11-CDG.
Neurobiology of aging.
1987
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Periventricular lucencies in the CT scans of aged and demented patients.
Biological psychiatry.
1986
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Leukoencephalopathy in normal and pathologic aging: 1. CT of brain lucencies.
AJNR. American journal of neuroradiology.
1986
Academic Article
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Leukoencephalopathy in normal and pathologic aging: 2. MRI of brain lucencies.
AJNR. American journal of neuroradiology.
1986
Academic Article
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Reduced incidence of left-handedness in clinically diagnosed dementia of the Alzheimer type.
Neurobiology of aging.
1986
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Periventricular high signal lesions and signal void on magnetic resonance imaging in hydrocephalus. Diagnostic and prognostic significance.
Acta radiologica. Supplementum.
1986
Academic Article
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Positron emission tomography of hydrocephalus. Metabolic effects of shunt procedures.
Acta radiologica. Supplementum.
1986
Academic Article
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Familial nature of Alzheimer's disease?.
The New England journal of medicine.
1984
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Positron emission tomography and computed tomography assessments of the aging human brain.
Journal of computer assisted tomography.
1984
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Wandering and parietal signs in senile dementia of Alzheimer's type.
Neuropsychobiology.
1984
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CT prognostic criteria of survival after malignant glioma surgery.
AJNR. American journal of neuroradiology.
1983
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Positron emission tomographic studies of aging and Alzheimer disease.
AJNR. American journal of neuroradiology.
1983
Academic Article
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Regional correlation of PET and CT in senile dementia of the Alzheimer type.
AJNR. American journal of neuroradiology.
1983
Academic Article
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Effects of naloxone in senile dementia: a double-blind trial.
The New England journal of medicine.
1983
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Computed tomography in aging and senile dementia of the Alzheimer type.
Advances in neurology.
1983
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Novel pharmacologic approaches to the treatment of senile dementia of the Alzheimer's type (SDAT).
Psychopharmacology bulletin.
1983
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Positron emission tomography in dementia.
Advances in neurology.
1983
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Relationship between cognition and mood in geriatric depression.
Psychopharmacology bulletin.
1982
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The Global Deterioration Scale for assessment of primary degenerative dementia.
The American journal of psychiatry.
1982
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18F-2-deoxy-2-fluoro-D-glucose as a tracer in the positron emission tomographic study of senile dementia.
The American journal of psychiatry.
1982
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Parenchymal CT correlates of senile dementia (Alzheimer disease): loss of gray-white matter discriminability.
AJNR. American journal of neuroradiology.
1981
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Central amine metabolism in Alzheimer's disease: in vivo relationship to cognitive deficit.
Neurobiology of aging.
1981
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The relationship between psychiatric assessments and cognitive test measures in mild to moderately cognitively impaired elderly [proceedings].
Psychopharmacology bulletin.
1981
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Computed tomography evaluations of brain-behavior relationships in senile dementia of the Alzheimer's type.
Neurobiology of aging.
1980
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Correlations between computerised tomographic changes and behavioural deficits in senile dementia.
Lancet (London, England).
1979
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