selected publications
- Checkpoint kinase 2 controls insulin secretion and glucose homeostasis. Nature chemical biology. 2023 Academic Article GET IT
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Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans.
Nature medicine.
2019
Academic Article
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Times cited: 115 -
Apoptotic β-cells induce macrophage reprogramming under diabetic conditions.
The Journal of biological chemistry.
2018
Academic Article
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Times cited: 19 -
Stigmasterol prevents glucolipotoxicity induced defects in glucose-stimulated insulin secretion.
Scientific reports.
2018
Academic Article
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Times cited: 40 -
Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis.
Journal of cellular and molecular medicine.
2017
Academic Article
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Times cited: 26 -
Multifunctional in vivo imaging of pancreatic islets during diabetes development.
Journal of cell science.
2016
Academic Article
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Times cited: 22 -
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.
The Journal of cell biology.
2012
Academic Article
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Times cited: 217 -
Cholesterol accumulation increases insulin granule size and impairs membrane trafficking.
Traffic (Copenhagen, Denmark).
2012
Academic Article
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Times cited: 69 -
Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocation.
The Journal of biological chemistry.
2012
Academic Article
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Times cited: 46 -
Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.
The Journal of biological chemistry.
2009
Academic Article
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Times cited: 45 -
Multi-photon excitation imaging of dynamic processes in living cells and tissues.
Reviews of physiology, biochemistry and pharmacology.
2008
Review
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Times cited: 45 -
Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis.
American journal of physiology. Cell physiology.
2007
Academic Article
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Times cited: 119 -
Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction.
Diabetes.
2007
Academic Article
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Times cited: 199 -
Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells.
Molecular biology of the cell.
2007
Academic Article
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Times cited: 36 -
Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect.
Traffic (Copenhagen, Denmark).
2006
Academic Article
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Times cited: 54 -
Regulation of two insulin granule populations within the reserve pool by distinct calcium sources.
Journal of cell science.
2005
Academic Article
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Times cited: 37 -
Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes.
The Journal of biological chemistry.
2004
Academic Article
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Times cited: 83 -
Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure.
The Journal of biological chemistry.
2002
Academic Article
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Times cited: 111 -
Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells.
The Journal of biological chemistry.
2002
Academic Article
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Times cited: 90 -
Cholesterol depletion induces large scale domain segregation in living cell membranes.
Proceedings of the National Academy of Sciences of the United States of America.
2001
Academic Article
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Times cited: 253 -
Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle.
The Journal of biological chemistry.
2001
Academic Article
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Times cited: 235 -
Characterization of rapid membrane internalization and recycling.
The Journal of biological chemistry.
2000
Academic Article
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Times cited: 198