selected publications
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Design and rationale for the life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study in patients with chronic myeloid leukemia.
BMC cancer.
2018
Academic Article
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Times cited: 17 - Running the marathon of chronic myeloid leukemia with no shoes (or without the right shoes)!. Cancer. 2017 Editorial Article GET IT
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Overall survival with ponatinib versus allogeneic stem cell transplantation in Philadelphia chromosome-positive leukemias with the T315I mutation.
Cancer.
2017
Academic Article
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Times cited: 80 -
Can any patients with chronic myeloid leukemia outside of a clinical trial have their tyrosine kinase inhibitor discontinued?.
Current opinion in hematology.
2017
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Times cited: 1 - Chronic myeloid leukemia: Is it dusk or dawn?. Best practice & research. Clinical haematology. 2016 Editorial Article GET IT
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Pleural Effusion in Dasatinib-Treated Patients With Chronic Myeloid Leukemia in Chronic Phase: Identification and Management.
Clinical lymphoma, myeloma & leukemia.
2016
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Times cited: 34 -
Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis.
The New England journal of medicine.
2016
Academic Article
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Times cited: 218 -
Long-term evaluation of cardiac and vascular toxicity in patients with Philadelphia chromosome-positive leukemias treated with bosutinib.
American journal of hematology.
2016
Academic Article
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Times cited: 73 -
Cross-Intolerance With Dasatinib Among Imatinib-Intolerant Patients With Chronic Phase Chronic Myeloid Leukemia.
Clinical lymphoma, myeloma & leukemia.
2016
Academic Article
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Times cited: 9 -
Evaluating the Impact of a Switch to Nilotinib on Imatinib-Related Chronic Low-Grade Adverse Events in Patients With CML-CP: The ENRICH Study.
Clinical lymphoma, myeloma & leukemia.
2016
Academic Article
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Times cited: 29 -
BCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase.
Leukemia.
2015
Academic Article
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Times cited: 58 -
The role of observational studies in optimizing the clinical management of chronic myeloid leukemia.
Therapeutic advances in hematology.
2015
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Times cited: 22 -
Cardiovascular and pulmonary adverse events in patients treated with BCR-ABL inhibitors: Data from the FDA Adverse Event Reporting System.
American journal of hematology.
2015
Academic Article
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Times cited: 38 - Extending the reach of nilotinib in chronic myeloid leukemia. Haematologica. 2014 Editorial Article GET IT
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Integrating current treatment options for TKI-resistant chronic myeloid leukemia.
Clinical advances in hematology & oncology : H&O.
2014
Academic Article
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Times cited: 1 - The challenge of the 'C' in CML. Leukemia research. 2013 Editorial Article GET IT
- Sequential therapy in chronic myelogenous leukemia: where do emerging therapies fit within current treatment regimens?. Clinical advances in hematology & oncology : H&O. 2013 Information Resource GET IT
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Striving to achieve safe, permanent treatment discontinuation in chronic myeloid leukemia.
Leukemia research.
2013
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Times cited: 8 -
The BCR-ABLT315I mutation compromises survival in chronic phase chronic myelogenous leukemia patients resistant to tyrosine kinase inhibitors, in a matched pair analysis.
Haematologica.
2013
Academic Article
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Times cited: 59 -
Ponatinib in patients with refractory acute myeloid leukaemia: findings from a phase 1 study.
British journal of haematology.
2013
Article
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Times cited: 56 -
T315I, more or less, predicts for major molecular response: the devil is in the details!.
Haematologica.
2013
Editorial Article
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Times cited: 3 -
Analysis of the potential effect of ponatinib on the QTc interval in patients with refractory hematological malignancies.
Cancer chemotherapy and pharmacology.
2013
Academic Article
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Times cited: 22 -
Predictive factors for successful imatinib cessation in chronic myeloid leukemia patients treated with imatinib.
American journal of hematology.
2013
Academic Article
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Times cited: 48 -
Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: a retrospective cohort analysis.
Leukemia.
2013
Academic Article
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Times cited: 151 -
Overcoming resistance in chronic myelogenous leukemia.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.
2013
Information Resource
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Times cited: 1 -
Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop.
Leukemia & lymphoma.
2012
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Times cited: 10 -
Ponatinib in refractory Philadelphia chromosome-positive leukemias.
The New England journal of medicine.
2012
Academic Article
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Times cited: 648 -
Current practices in the management of chronic myeloid leukemia.
Clinical lymphoma, myeloma & leukemia.
2012
Academic Article
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Times cited: 10 -
Clinical roundtable monograph: Emerging treatment options for TKI-resistant chronic myelogenous leukemia.
Clinical advances in hematology & oncology : H&O.
2012
Academic Article
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Times cited: 5 -
Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias.
Blood.
2011
Academic Article
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Times cited: 55 -
Practical management of patients with chronic myeloid leukemia.
Cancer.
2011
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Times cited: 23 -
Intolerance to tyrosine kinase inhibitors in chronic myeloid leukemia: Definitions and clinical implications.
Cancer.
2010
Information Resource
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Times cited: 51 -
Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation.
Blood.
2009
Academic Article
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Times cited: 107 -
Management of drug toxicities in chronic myeloid leukaemia.
Best practice & research. Clinical haematology.
2009
Information Resource
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Times cited: 35 -
Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib.
Blood.
2009
Academic Article
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Times cited: 71 - Response dynamics in chronic-phase chronic myeloid leukemia. Clinical lymphoma & myeloma. 2009 Information Resource GET IT
- Tailoring tyrosine kinase inhibitor therapy in chronic myeloid leukemia. Cancer control : journal of the Moffitt Cancer Center. 2009 Information Resource GET IT
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Appropriate sequencing of tyrosine kinase inhibitors in chronic myelogenous leukemia: when to change? A perspective in 2009.
Current opinion in hematology.
2009
Information Resource
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Times cited: 6 -
An activating KRAS mutation in imatinib-resistant chronic myeloid leukemia.
Leukemia.
2008
Article
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Times cited: 27 -
A half-log increase in BCR-ABL RNA predicts a higher risk of relapse in patients with chronic myeloid leukemia with an imatinib-induced complete cytogenetic response.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2007
Academic Article
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Times cited: 107 -
Mutational analysis and overcoming imatinib resistance in chronic myeloid leukemia with novel tyrosine kinase inhibitors.
Current treatment options in oncology.
2007
Information Resource
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Times cited: 1 -
Mutations of the BCR-ABL-kinase domain occur in a minority of patients with stable complete cytogenetic response to imatinib.
Leukemia.
2007
Academic Article
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Times cited: 71 - Stem cell transplantation in patients with chronic myelogenous leukemia: when should it be used?. Mayo Clinic proceedings. 2006 Information Resource GET IT
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BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML.
Blood.
2006
Academic Article
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Times cited: 113 -
Defining and managing imatinib resistance.
Hematology. American Society of Hematology. Education Program.
2006
Information Resource
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Times cited: 74 - Baseline disease risk and response to therapy in chronic myeloid leukemia: necessary predictive tools then and now. Haematologica. 2005 Article GET IT
- Chronic myeloid leukemia: current application of cytogenetics and molecular testing for diagnosis and treatment. Mayo Clinic proceedings. 2005 Information Resource GET IT
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Ph-positive and -negative myeloproliferative syndromes may co-exist.
Leukemia.
2004
Article
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Times cited: 7 -
Thienopyridine-linked thrombotic microangiopathy: association with endothelial cell apoptosis and activation of MAP kinase signalling cascades.
British journal of haematology.
2004
Academic Article
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Times cited: 32 -
Clonal evolution and lack of cytogenetic response are adverse prognostic factors for hematologic relapse of chronic phase CML patients treated with imatinib mesylate.
Blood.
2003
Academic Article
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Times cited: 99 -
In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines.
Blood.
2003
Academic Article
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Times cited: 85 -
STI571 as a targeted therapy for CML.
Cancer investigation.
2003
Information Resource
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Times cited: 53 -
Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate.
Leukemia.
2003
Academic Article
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Times cited: 102 -
The impact of clonal evolution on response to imatinib mesylate (STI571) in accelerated phase CML.
Blood.
2002
Academic Article
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Times cited: 114 -
Hematopathologic and cytogenetic findings in imatinib mesylate-treated chronic myelogenous leukemia patients: 14 months' experience.
Blood.
2002
Academic Article
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Times cited: 94 -
Recent advancements in the treatment of chronic myelogenous leukemia.
Annual review of medicine.
2002
Information Resource
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Times cited: 58 -
ST1571, a tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia: validating the promise of molecularly targeted therapy.
Cancer chemotherapy and pharmacology.
2001
Academic Article
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Times cited: 27 -
STI571: a gene product-targeted therapy for leukemia.
Current oncology reports.
2001
Information Resource
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Times cited: 33 -
Chronic myelogenous leukemia.
Current opinion in oncology.
2001
Information Resource
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Times cited: 78 -
Role of transforming growth factor beta1 in microvascular endothelial cell apoptosis associated with thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome.
American journal of hematology.
2001
Academic Article
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Times cited: 17