Muthukumar, Thangamani

Publications

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selected publications

Blockade of store-operated calcium entry by BTP2 preserves anti-inflammatory gene expression in human peripheral blood mononuclear cells. Human immunology. 2024 Academic Article GET IT
Quantification of Multi-Compartment Flow with Spectral Diffusion MRI. 2024 GET IT
Activating the Flozin Shield: Cardioprotective Effects of Sodium-Glucose Cotransporter-2 Inhibitors in Kidney Transplant Recipients With Diabetes Mellitus. Kidney international reports. 2024 Editorial Article GET IT
A universal urinary cell gene signature of acute rejection in kidney allografts. Journal of immunological methods. 2024 Academic Article GET IT
RNA-sequencing of Human Kidney Allografts and Delineation of T-Cell Genes, Gene Sets, and Pathways Associated With Acute T Cell-mediated Rejection. Transplantation. 2024 Academic Article GET IT
Urinary Cell Gene Signature of Acute Rejection in Kidney Allografts. 2023 GET IT
Transcriptomic signatures of chronic active antibody-mediated rejection deciphered by RNA sequencing of human kidney allografts. Kidney international. 2023 Academic Article GET IT
Partners in Crime: Inferring Cell-to-cell Interactions in Kidney Allograft Rejection From Single-cell RNA Sequencing. Transplantation. 2023 Academic Article GET IT
Transmission of yellow fever vaccine virus through blood transfusion and organ transplantation in the USA in 2021: report of an investigation. The Lancet. Microbe. 2023 Academic Article GET IT
Haploidentical allogeneic stem cell transplantation with post-transplant cyclophosphamide and subsequent kidney transplant for patients with severe sickle cell disease with end-stage kidney disease (ESKD). Bone marrow transplantation. 2023 Letter GET IT
Times cited: 14
Standardization and Interpretation of RNA-sequencing for Transplantation. Transplantation. 2023 Academic Article GET IT
Times cited: 40
Single nuclei transcriptomics delineates complex immune and kidney cell interactions contributing to kidney allograft fibrosis. Kidney international. 2023 Academic Article GET IT
Complications of rabbit anti-thymocyte globulin induction immunosuppression in HIV-infected kidney transplant recipients. Frontiers in nephrology. 2022 Academic Article GET IT
Urinary cell mRNA profiling of kidney allograft recipients: Development of a portable protocol for noninvasive diagnosis of T cell mediated rejection and BK virus nephropathy. Journal of immunological methods. 2022 Academic Article GET IT
The ABCD of Kidney Allograft Pathology-The Beginning of the Beginning. Journal of the American Society of Nephrology : JASN. 2022 Academic Article GET IT
Times cited: 2
Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2022 Academic Article GET IT
Times cited: 5
Urinary cell mRNA profiling distinguishes disease activity in antineutrophil cytoplasmic antibody-associated glomerulonephritis. Journal of nephrology. 2022 Letter GET IT
Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts. PloS one. 2022 Academic Article GET IT
Post-Transplant Hypotension in Kidney Recipients-Vasopressin to the Rescue?. Kidney international reports. 2022 Editorial Article GET IT
Times cited: 1
Principles of Virtual Crossmatch Testing for Kidney Transplantation. Kidney international reports. 2022 Review GET IT
Times cited: 15
Clinically adjudicated deceased donor acute kidney injury and graft outcomes. PloS one. 2022 Academic Article GET IT
Times cited: 4
Imagining a Better Outcome for Chronic Antibody-Mediated Rejection-Will Blocking Interleukin-6 Signaling Help?. Kidney international reports. 2022 Editorial Article GET IT
Times cited: 75
Conditional deletion of myeloid-specific mitofusin 2 but not mitofusin 1 promotes kidney fibrosis. Kidney international. 2022 Academic Article GET IT
Times cited: 21
T-Cell-Positive, B-Cell-Negative Flow Cytometry Crossmatch: Frequency, HLA Locus Specificity, and Mechanisms Among 3073 Clinical Flow Cytometry Crossmatch Tests. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 2022 Academic Article GET IT
Casirivimab-Imdevimab (REGN-COV2) for Mild-to-Moderate SARS-CoV2 Infection in Kidney Transplant Recipients. Kidney international reports. 2021 Academic Article GET IT
Kidney Allograft Function Is a Confounder of Urine Metabolite Profiles in Kidney Allograft Recipients. Metabolites. 2021 Academic Article GET IT
FOXP3 mRNA Profile Prognostic of Acute T Cell-mediated Rejection and Human Kidney Allograft Survival. Transplantation. 2021 Academic Article GET IT
Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study. Kidney360. 2021 Academic Article GET IT
Times cited: 11
Serum MicroRNA Transcriptomics and Acute Rejection or Recurrent Hepatitis C Virus in Human Liver Allograft Recipients: A Pilot Study. Transplantation. 2021 Academic Article GET IT
Deep sequencing of DNA from urine of kidney allograft recipients to estimate donor/recipient-specific DNA fractions. PloS one. 2021 Academic Article GET IT
Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes. Transplantation. 2021 Academic Article GET IT
Times cited: 11
Deceased-Donor Acute Kidney Injury and BK Polyomavirus in Kidney Transplant Recipients. Clinical journal of the American Society of Nephrology : CJASN. 2021 Academic Article GET IT
Times cited: 5
Dissecting the human kidney allograft transcriptome: single-cell RNA sequencing. Current opinion in organ transplantation. 2021 Review GET IT
Times cited: 8
Validation of a noninvasive prognostic signature for allograft failure following BK virus associated nephropathy. Clinical transplantation. 2021 Academic Article GET IT
Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation. BMC nephrology. 2021 Academic Article GET IT
Times cited: 9
Anticoagulation Strategies and Filter Life in COVID-19 Patients Receiving Continuous Renal Replacement Therapy: A Single-Center Experience. Clinical journal of the American Society of Nephrology : CJASN. 2020 Article GET IT
Times cited: 31
Urinary Cell Transcriptome Profiling and Identification of ITM2A, SLAMF6, and IKZF3 as Biomarkers of Acute Rejection in Human Kidney Allografts. Transplantation direct. 2020 Academic Article GET IT
Times cited: 8
Kidney allograft recipients, immunosuppression, and coronavirus disease-2019: a report of consecutive cases from a New York City transplant center. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2020 Academic Article GET IT
Times cited: 67
Urine Injury Biomarkers Are Not Associated With Kidney Transplant Failure. Transplantation. 2020 Academic Article GET IT
Times cited: 11
Urinary cell transcriptomics and acute rejection in human kidney allografts. JCI insight. 2020 Academic Article GET IT
Times cited: 26
Incidence and Risk Factors for Acute and Chronic Kidney Injury after Adult Cord Blood Transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2020 Academic Article GET IT
Times cited: 4
Molecular determinants of nephron vascular specialization in the kidney. Nature communications. 2019 Academic Article GET IT
Times cited: 81
Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis. JCI insight. 2019 Academic Article GET IT
Times cited: 113
Butyrate-producing gut bacteria and viral infections in kidney transplant recipients: A pilot study. Transplant infectious disease : an official journal of the Transplantation Society. 2019 Academic Article GET IT
Times cited: 42
Landscape of innate immune system transcriptome and acute T cell-mediated rejection of human kidney allografts. JCI insight. 2019 Academic Article GET IT
Times cited: 33
Antibiotic prophylaxis for ureteral stent removal after kidney transplantation. Clinical transplantation. 2019 Academic Article GET IT
Times cited: 7
MicroRNAs and Transplantation. Clinics in laboratory medicine. 2018 Information Resource GET IT
Times cited: 23
Deceased-donor acute kidney injury is not associated with kidney allograft failure. Kidney international. 2018 Academic Article GET IT
Times cited: 65
Management of Patients with Acute Methotrexate Nephrotoxicity with High-Dose Leucovorin. Pharmacotherapy. 2018 Academic Article GET IT
Times cited: 21
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction. JCI insight. 2018 Academic Article GET IT
Times cited: 136
Single nucleotide variant counts computed from RNA sequencing and cellular traffic into human kidney allografts. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2018 Academic Article GET IT
Times cited: 11
Bortezomib for Reduction of Proteinuria in IgA Nephropathy. Kidney international reports. 2018 Academic Article GET IT
Times cited: 39
RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase. JCI insight. 2018 Academic Article GET IT
Times cited: 77
Kidney allograft failure in the steroid-free immunosuppression era: A matched case-control study. Clinical transplantation. 2017 Academic Article GET IT
Times cited: 4
In-Hospital Cardiovascular Complications After Pancreas Transplantation in the United States from 2003 to 2012. The American journal of cardiology. 2017 Academic Article GET IT
Times cited: 8
The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2017 Academic Article GET IT
Times cited: 537
Exome Sequencing and Prediction of Long-Term Kidney Allograft Function. PLoS computational biology. 2016 Academic Article GET IT
Times cited: 44
Development and validation of a prognostic index for allograft outcome in kidney recipients with transplant glomerulopathy. Kidney international. 2016 Academic Article GET IT
Times cited: 26
Urine Metabolite Profiles Predictive of Human Kidney Allograft Status. Journal of the American Society of Nephrology : JASN. 2015 Academic Article GET IT
Times cited: 55
Characteristics of Circulating Donor Human Leukocyte Antigen-specific Immunoglobulin G Antibodies Predictive of Acute Antibody-mediated Rejection and Kidney Allograft Failure. Transplantation. 2015 Academic Article GET IT
Times cited: 50
Gut microbiota and tacrolimus dosing in kidney transplantation. PloS one. 2015 Academic Article GET IT
Times cited: 148
Gut microbial community structure and complications after kidney transplantation: a pilot study. Transplantation. 2014 Academic Article GET IT
Times cited: 154
Circulating levels of 25-hydroxyvitamin D and acute cellular rejection in kidney allograft recipients. Transplantation. 2014 Academic Article GET IT
Times cited: 50
Allograft rejection and tubulointerstitial fibrosis in human kidney allografts: interrogation by urinary cell mRNA profiling. Transplantation reviews (Orlando, Fla.). 2014 Information Resource GET IT
Times cited: 8
Urinary cell mRNA profiles and differential diagnosis of acute kidney graft dysfunction. Journal of the American Society of Nephrology : JASN. 2014 Academic Article GET IT
Times cited: 39
Urinary cell mRNA profiles predictive of human kidney allograft status. Immunological reviews. 2014 Information Resource GET IT
Times cited: 41
Urinary-cell mRNA and acute kidney-transplant rejection. The New England journal of medicine. 2013 Article GET IT
Times cited: 14
Independent risk factors for urinary tract infection and for subsequent bacteremia or acute cellular rejection: a single-center report of 1166 kidney allograft recipients. Transplantation. 2013 Academic Article GET IT
Times cited: 123
On the detection of anti-HLA antibodies using single antigen bead Luminex assay: lot-to-lot variations in MFI. Transplantation. 2013 Article GET IT
Times cited: 17
Noninvasive prognostication of polyomavirus BK virus-associated nephropathy. Transplantation. 2013 Academic Article GET IT
Times cited: 21
Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. The New England journal of medicine. 2013 Academic Article GET IT
Times cited: 278
HIV-infected kidney graft recipients managed with an early corticosteroid withdrawal protocol: clinical outcomes and messenger RNA profiles. Transplantation. 2013 Academic Article GET IT
Times cited: 13
Excellent outcomes with expanded criteria donor kidneys: the role of the recipient's age. Clinical transplants. 2013 Academic Article GET IT
MicroRNA sequence profiles of human kidney allografts with or without tubulointerstitial fibrosis. Transplantation. 2012 Academic Article GET IT
Times cited: 99
Papillary necrosis with invasive fungal infections: a case series of 29 patients. Clinical kidney journal. 2012 Academic Article GET IT
Times cited: 5
Concurrent acute cellular rejection is an independent risk factor for renal allograft failure in patients with C4d-positive antibody-mediated rejection. Transplantation. 2012 Academic Article GET IT
Times cited: 37
Discovery and validation of a molecular signature for the noninvasive diagnosis of human renal allograft fibrosis. Transplantation. 2012 Academic Article GET IT
Times cited: 36
Dendritic cells with TGF-β1 and IL-2 differentiate naive CD4+ T cells into alloantigen-specific and allograft protective Foxp3+ regulatory T cells. Transplantation. 2012 Academic Article GET IT
Times cited: 15
Urinary cell levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and acute rejection of human renal allografts. Transplantation. 2010 Academic Article GET IT
Times cited: 52
MicroRNAs: small RNAs with big effects. Transplantation. 2010 Information Resource GET IT
Times cited: 139
Validation of noninvasive diagnosis of BK virus nephropathy and identification of prognostic biomarkers. Transplantation. 2010 Academic Article GET IT
Times cited: 58
Noninvasive diagnosis of acute rejection of renal allografts. Current opinion in organ transplantation. 2010 Information Resource GET IT
Times cited: 72
Epidemiology of BK virus in renal allograft recipients: independent risk factors for BK virus replication. Transplantation. 2008 Academic Article GET IT
Times cited: 105
Messenger RNA for FOXP3 in the urine of renal-allograft recipients. The New England journal of medicine. 2005 Academic Article GET IT
Times cited: 466
Measurement of apoptosis of intact human islets by confocal optical sectioning and stereologic analysis of YO-PRO-1-stained islets. Transplantation. 2005 Academic Article GET IT
Times cited: 20
Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine. Kidney international. 2004 Academic Article GET IT
Times cited: 155
Optimization of RNA yield, purity and mRNA copy number by treatment of urine cell pellets with RNAlater. Journal of immunological methods. 2003 Academic Article GET IT
Times cited: 37
Molecular signatures of urinary cells distinguish acute rejection of renal allografts from urinary tract infection. Transplantation. 2003 Academic Article GET IT
Times cited: 45
Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation. 2003 Academic Article GET IT
Times cited: 58
Vesicoureteric reflux and reflux nephropathy as seen at a tertiary care adult nephrology service in India--an analysis of 86 patients. Renal failure. 2003 Academic Article GET IT
Times cited: 6
Prognostic factors in immunoglobulin-A nephropathy. The Journal of the Association of Physicians of India. 2002 Academic Article GET IT
Times cited: 7
Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation. 2002 Academic Article GET IT
Times cited: 107
Acute renal failure due to rifampicin: a study of 25 patients. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2002 Academic Article GET IT
Times cited: 79
Enforced c-REL deficiency prolongs survival of islet allografts1. Transplantation. 2002 Academic Article GET IT
Times cited: 28
Impact of cyclosporine withdrawal on living related renal transplants: a single-center experience. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2001 Academic Article GET IT
Times cited: 22
Isoniazid does not affect bioavailability of cyclosporine in renal transplant recipients. Methods and findings in experimental and clinical pharmacology. 2000 Academic Article GET IT
Times cited: 14
Treatment-related acute renal failure in the elderly: a hospital-based prospective study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2000 Academic Article GET IT
Times cited: 141
Acute renal failure due to nontraumatic rhabdomyolysis following binge drinking. Renal failure. 1999 Review GET IT
Times cited: 21
Familial distal renal tubular acidosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1999 Letter GET IT
Times cited: 2

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Research

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Co-investigator Network

Funding awarded

Characterization of Renal Allograft Fibrosis and Prediction of Outcome Using a Quantitative MRI Approach awarded by Pershing Square Sohn Cancer Research Alliance, The Co-Investigator 2021 - 2026
Mechanisms of intracellular iron dysregulation in kidney fibrosis and reno-protective strategies awarded by National Institute of Diabetes & Digestive & Kidney Diseases Co-Investigator 2024 - 2025
Multianalyte Profiling of Kidney Allograft Recipients (Biopharma) awarded by CareDx, Inc. Co-Investigator 2020 - 2024
missing activity Co-Investigator 2017 - 2024

Optimization of UroMap awarded by CareDx, Inc. Key Personnel 2023 - 2028

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Background

education and training

M.S., Weill Cornell Graduate School of Medical Sciences 2014
M.D., Stanley Medical College, Dr M.G.R Medical University (India) 1994
M.B.,B.S., Madras Medical College, University of Madras (India) 1988

Contact

full name

Thangamani Muthukumar

primary email

mut9002@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Thangamani Muthukumar Associate Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage