selected publications
- FREE FATTY ACIDS INHIBIT AN ION-COUPLED MEMBRANE TRANSPORTER BY DISSIPATING THE ION GRADIENT. The Journal of biological chemistry. 2024 Academic Article GET IT
- Structural basis of the excitatory amino acid transporter 3 substrate recognition. 2024 GET IT
- HS-AFM single-molecule structural biology uncovers basis of transporter wanderlust kinetics. Nature structural & molecular biology. 2024 Academic Article GET IT
- Ion and lipid orchestration of secondary active transport. Nature. 2024 Review GET IT
- Author Correction: Structural basis of pH-dependent activation in a CLC transporter. 2024 GET IT
- Structural basis of pH-dependent activation in a CLC transporter. Nature structural & molecular biology. 2024 Academic Article GET IT
- Uncoupled substrate binding underlies the evolutionary switch between Na + and H + -coupled prokaryotic aspartate transporters. 2023 GET IT
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Symport and antiport mechanisms of human glutamate transporters.
Nature communications.
2023
Academic Article
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Times cited: 9 - Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM. Journal of the American Chemical Society. 2023 Academic Article GET IT
- The archaeal glutamate transporter homologue GltPh shows heterogeneous substrate binding. The Journal of general physiology. 2022 Academic Article GET IT
- Linking function to global and local dynamics in an elevator-type transporter. Proceedings of the National Academy of Sciences of the United States of America. 2021 Academic Article GET IT
- FRET-based Microscopy Assay to Measure Activity of Membrane Amino Acid Transporters with Single-transporter Resolution. Bio-protocol. 2021 Academic Article GET IT
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Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport.
Science advances.
2021
Academic Article
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Times cited: 31 -
The high-energy transition state of the glutamate transporter homologue GltPh.
The EMBO journal.
2020
Academic Article
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Times cited: 16 -
Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters.
eLife.
2020
Academic Article
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Times cited: 34 -
Millisecond dynamics of an unlabeled amino acid transporter.
Nature communications.
2020
Academic Article
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Times cited: 30 -
Use of paramagnetic 19F NMR to monitor domain movement in a glutamate transporter homolog.
Nature chemical biology.
2020
Academic Article
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Times cited: 33 -
Single-molecule transport kinetics of a glutamate transporter homolog shows static disorder.
Science advances.
2020
Academic Article
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Times cited: 22 -
Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh.
eLife.
2018
Academic Article
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Times cited: 28 -
A facile approach for the in vitro assembly of multimeric membrane transport proteins.
eLife.
2018
Academic Article
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Times cited: 16 - Structural basis of sterol binding and transport by a yeast StARkin domain. The Journal of biological chemistry. 2018 Academic Article GET IT
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Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nature communications.
2018
Academic Article
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Times cited: 59 -
Direct visualization of glutamate transporter elevator mechanism by high-speed AFM.
Proceedings of the National Academy of Sciences of the United States of America.
2017
Academic Article
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Times cited: 96 -
The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters.
PloS one.
2015
Academic Article
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Times cited: 13 -
Isothermal titration calorimetry of ion-coupled membrane transporters.
Methods (San Diego, Calif.).
2015
Academic Article
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Times cited: 21 -
Transport domain unlocking sets the uptake rate of an aspartate transporter.
Nature.
2015
Academic Article
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Times cited: 131 -
Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
eLife.
2014
Academic Article
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Times cited: 89 -
Transport dynamics in a glutamate transporter homologue.
Nature.
2013
Academic Article
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Times cited: 141 -
Chemical catalysis by the translocator protein (18 kDa).
Biochemistry.
2013
Academic Article
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Times cited: 25 -
Binding thermodynamics of a glutamate transporter homolog.
Nature structural & molecular biology.
2013
Academic Article
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Times cited: 73 -
Conformational ensemble of the sodium-coupled aspartate transporter.
Nature structural & molecular biology.
2013
Academic Article
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Times cited: 108 -
Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog.
Nature structural & molecular biology.
2012
Academic Article
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Times cited: 133 -
Structural perspectives on secondary active transporters.
Trends in pharmacological sciences.
2010
Information Resource
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Times cited: 118 -
Transport mechanism of a bacterial homologue of glutamate transporters.
Nature.
2009
Academic Article
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Times cited: 358 -
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature.
2007
Academic Article
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Times cited: 366 -
Trimeric subunit stoichiometry of the glutamate transporters from Bacillus caldotenax and Bacillus stearothermophilus.
Biochemistry.
2003
Academic Article
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Times cited: 77 -
Isolation and characterization of IIAChb, a soluble protein of the enzyme II complex required for the transport/phosphorylation of N, N'-diacetylchitobiose in Escherichia coli.
The Journal of biological chemistry.
2000
Academic Article
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Times cited: 17 -
The structural stability of the co-chaperonin GroES.
Journal of molecular biology.
1997
Academic Article
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Times cited: 67 -
Detection and characterization of ceramide-1-phosphate phosphatase activity in rat liver plasma membrane.
The Journal of biological chemistry.
1993
Academic Article
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Times cited: 65