selected publications
- The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel. Proceedings of the National Academy of Sciences of the United States of America. 2025 Academic Article GET IT
- Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1. Nature communications. 2023 Academic Article GET IT
- Anionic lipids unlock the gates of select ion channels in the pacemaker family. Nature structural & molecular biology. 2022 Academic Article GET IT
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Mechanistic insights into volatile anesthetic modulation of K2P channels.
eLife.
2020
Academic Article
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Times cited: 21 -
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
Trends in pharmacological sciences.
2019
Information Resource
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Times cited: 187 -
HCN and K2P Channels in Anesthetic Mechanisms Research.
Methods in enzymology.
2018
Article
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Times cited: 7 -
Clinical improvement associated with targeted interruption of the cerebellothalamic tract following MR-guided focused ultrasound for essential tremor.
Journal of neurosurgery.
2017
Academic Article
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Times cited: 48 - Relevance of Clinical Relevance. Anesthesiology. 2016 Article GET IT
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Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.
Neuron.
2014
Academic Article
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Times cited: 105 -
Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).
The Journal of biological chemistry.
2010
Academic Article
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Times cited: 24 -
Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1.
Molecular and biochemical parasitology.
2009
Academic Article
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Times cited: 30 -
Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE.
Molecular and biochemical parasitology.
2009
Academic Article
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Times cited: 65 -
Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum.
The Journal of biological chemistry.
2008
Academic Article
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Times cited: 44 -
Differential protein mobility of the gamma-aminobutyric acid, type A, receptor alpha and beta subunit channel-lining segments.
The Journal of biological chemistry.
2004
Academic Article
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Times cited: 21