Razlighi, Ray

Publications

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selected publications

Increased between-network connectivity: A risk factor for tau elevation and disease progression. Neuroscience letters. 2024 Academic Article GET IT
Reduction in Constitutively Activated Auditory Brainstem Microglia in Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024 Academic Article GET IT
Remote Associations Between Tau and Cortical Amyloid-β Are Stage-Dependent. Journal of Alzheimer's disease : JAD. 2024 Academic Article GET IT
Pulsatility analysis of the circle of Willis. Aging brain. 2024 Academic Article GET IT
In vivo tau is associated with change in memory and processing speed, but not reasoning, in cognitively unimpaired older adults. Neurobiology of aging. 2023 Academic Article GET IT
Choroid Plexus Calcification Correlates with Cortical Microglial Activation in Humans: A Multimodal PET, CT, MRI Study. AJNR. American journal of neuroradiology. 2023 Academic Article GET IT
Distinct and joint effects of low and high levels of Aβ and tau deposition on cortical thickness. NeuroImage. Clinical. 2023 Academic Article GET IT
Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment. Alzheimer's research & therapy. 2023 Academic Article GET IT
Tau PET following acute TBI: Off-target binding to blood products, tauopathy, or both?. Frontiers in neuroimaging. 2022 Academic Article GET IT
Times cited: 104
Positron Emission Tomography reveals age-associated hypothalamic microglial activation in women. Scientific reports. 2022 Academic Article GET IT
Evidence suggesting common mechanisms underlie contralateral and ipsilateral negative BOLD responses in the human visual cortex. NeuroImage. 2022 Academic Article GET IT
Landmark-guided region-based spatial normalization for functional magnetic resonance imaging. Human brain mapping. 2022 Academic Article GET IT
Times cited: 3
Plasma Amyloid and in vivo Brain Amyloid in Late Middle-Aged Hispanics. Journal of Alzheimer's disease : JAD. 2022 Academic Article GET IT
Patterns of tau pathology identified with ¹⁸ F-MK-6240 PET imaging. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021 Academic Article GET IT
Times cited: 13
Predictive utility of task-related functional connectivity vs. voxel activation. PloS one. 2021 Academic Article GET IT
Attenuation of motion artifacts in fMRI using discrete reconstruction of irregular fMRI trajectories (DRIFT). Magnetic resonance in medicine. 2021 Academic Article GET IT
Sex differences in in vivo tau neuropathology in a multiethnic sample of late middle-aged adults. Neurobiology of aging. 2021 Academic Article GET IT
Times cited: 20
In Vivo Amyloid, Neurodegeneration, and Verbal Learning in Late Middle-Aged Hispanics. Journal of Alzheimer's disease : JAD. 2021 Academic Article GET IT
Topographical Overlapping of the Amyloid-β and Tau Pathologies in the Default Mode Network Predicts Alzheimer's Disease with Higher Specificity. Journal of Alzheimer's disease : JAD. 2021 Academic Article GET IT
Metabolic syndrome and its components in relation to in vivo brain amyloid and neurodegeneration in late middle age. Neurobiology of aging. 2020 Academic Article GET IT
Times cited: 12
Brain Amyloid Burden and Resting-State Functional Connectivity in Late Middle-Aged Hispanics. Frontiers in neurology. 2020 Academic Article GET IT
Times cited: 6
Apolipoprotein E genotype and in vivo amyloid burden in middle-aged Hispanics. Neurology. 2020 Academic Article GET IT
Times cited: 8
fMRI-guided white matter connectivity in fluid and crystallized cognitive abilities in healthy adults. NeuroImage. 2020 Academic Article GET IT
Times cited: 2
Cortical thickness and its associations with age, total cognition and education across the adult lifespan. PloS one. 2020 Academic Article GET IT
Times cited: 27
Towards an ontology of cognitive processes and their neural substrates: A structural equation modeling approach. PloS one. 2020 Academic Article GET IT
Times cited: 6
Antiviral therapy: Valacyclovir Treatment of Alzheimer's Disease (VALAD) Trial: protocol for a randomised, double-blind,placebo-controlled, treatment trial. BMJ open. 2020 Academic Article GET IT
Times cited: 40
Pre-Diabetes, but not Type 2 Diabetes, Is Related to Brain Amyloid in Late Middle-Age. Journal of Alzheimer's disease : JAD. 2020 Academic Article GET IT
Times cited: 19
Sex Differences in in vivo Alzheimer's Disease Neuropathology in Late Middle-Aged Hispanics. Journal of Alzheimer's disease : JAD. 2020 Academic Article GET IT
Times cited: 15
Task-evoked Negative BOLD Response and Functional Connectivity in the Default Mode Network are Representative of Two Overlapping but Separate Neurophysiological Processes. Scientific reports. 2019 Academic Article GET IT
Times cited: 17
Age specificity in fornix-to-hippocampus association. Brain imaging and behavior. 2019 Academic Article GET IT
Times cited: 11
Microglial activation, but not tau pathology, is independently associated with amyloid positivity and memory impairment. Neurobiology of aging. 2019 Academic Article GET IT
Times cited: 38
The Effect of Aging on Resting State Connectivity of Predefined Networks in the Brain. Frontiers in aging neuroscience. 2019 Academic Article GET IT
Times cited: 114
The relationship between white matter hyperintensities and cognitive reference abilities across the life span. Neurobiology of aging. 2019 Academic Article GET IT
Times cited: 25
The Benefit of Slice Timing Correction in Common fMRI Preprocessing Pipelines. Frontiers in neuroscience. 2019 Academic Article GET IT
Times cited: 28
Brain biomarkers and cognition across adulthood. Human brain mapping. 2019 Academic Article GET IT
Times cited: 22
A Fully Automatic Technique for Precise Localization and Quantification of Amyloid-β PET Scans. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 19
Effect of aerobic exercise on cognition in younger adults: A randomized clinical trial. Neurology. 2019 Academic Article GET IT
Times cited: 118
Between-network Functional Connectivity Is Modified by Age and Cognitive Task Domain. Journal of cognitive neuroscience. 2019 Academic Article GET IT
Times cited: 27
Task-Evoked Negative BOLD Response in the Default Mode Network Does Not Alter Its Functional Connectivity. Frontiers in computational neuroscience. 2018 Academic Article GET IT
Times cited: 5
A task-invariant cognitive reserve network. NeuroImage. 2018 Academic Article GET IT
Times cited: 82
Inhibitory Selection Mechanisms in Clinically Healthy Older and Younger Adults. The journals of gerontology. Series B, Psychological sciences and social sciences. 2018 Academic Article GET IT
Times cited: 8
Reference ability neural networks and behavioral performance across the adult life span. NeuroImage. 2018 Academic Article GET IT
Times cited: 10
Multiple pathways of reserve simultaneously present in cognitively normal older adults. Neurology. 2017 Academic Article GET IT
Times cited: 13
Cognitive Reserve and Brain Maintenance: Orthogonal Concepts in Theory and Practice. Cerebral cortex (New York, N.Y. : 1991). 2017 Academic Article GET IT
Times cited: 59
Dynamic Patterns of Brain Structure-Behavior Correlation Across the Lifespan. Cerebral cortex (New York, N.Y. : 1991). 2017 Academic Article GET IT
Times cited: 13
BOLD neurovascular coupling does not change significantly with normal aging. Human brain mapping. 2017 Academic Article GET IT
Times cited: 36
Brain atrophy can introduce age-related differences in BOLD response. Human brain mapping. 2017 Academic Article GET IT
Times cited: 15
Perceptual and memory inhibition deficits in clinically healthy older adults are associated with region-specific, doubly dissociable patterns of cortical thinning. Behavioral neuroscience. 2017 Academic Article GET IT
Times cited: 6
Optimal slice timing correction and its interaction with fMRI parameters and artifacts. Medical image analysis. 2016 Academic Article GET IT
Times cited: 30
Functional brain and age-related changes associated with congruency in task switching. Neuropsychologia. 2016 Academic Article GET IT
Times cited: 16
Selective association between cortical thickness and reference abilities in normal aging. NeuroImage. 2016 Academic Article GET IT
Times cited: 16
β-Amyloid Deposition Is Associated with Decreased Right Prefrontal Activation during Task Switching among Cognitively Normal Elderly. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 Academic Article GET IT
Times cited: 23
Differences between chronological and brain age are related to education and self-reported physical activity. Neurobiology of aging. 2016 Academic Article GET IT
Times cited: 152
The Reference Ability Neural Network Study: Life-time stability of reference-ability neural networks derived from task maps of young adults. NeuroImage. 2015 Academic Article GET IT
Times cited: 38
Mediterranean diet and brain structure in a multiethnic elderly cohort. Neurology. 2015 Academic Article GET IT
Times cited: 188
White matter tract covariance patterns predict age-declining cognitive abilities. NeuroImage. 2015 Academic Article GET IT
Times cited: 24
Aβ-related hyperactivation in frontoparietal control regions in cognitively normal elderly. Neurobiology of aging. 2015 Academic Article GET IT
Times cited: 26
Cognitive neuroscience neuroimaging repository for the adult lifespan. NeuroImage. 2015 Academic Article GET IT
Times cited: 15
Breadth and age-dependency of relations between cortical thickness and cognition. Neurobiology of aging. 2015 Academic Article GET IT
Times cited: 37
Brain Amyloid Deposition and Longitudinal Cognitive Decline in Nondemented Older Subjects: Results from a Multi-Ethnic Population. PloS one. 2015 Academic Article GET IT
Times cited: 32
Functional network mediates age-related differences in reaction time: a replication and extension study. Brain and behavior. 2015 Academic Article GET IT
Times cited: 3
Cerebral autoregulation, beta amyloid, and white matter hyperintensities are interrelated. Neuroscience letters. 2015 Academic Article GET IT
Times cited: 75
Making cognitive latent variables manifest: distinct neural networks for fluid reasoning and processing speed. Journal of cognitive neuroscience. 2014 Academic Article GET IT
Times cited: 18
Functional connectivity of the posterior hippocampus is more dominant as we age. Cognitive neuroscience. 2014 Academic Article GET IT
Times cited: 29
APOE ε4 and risk for Alzheimer's disease: do regionally distributed white matter hyperintensities play a role?. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2014 Academic Article GET IT
Times cited: 56
The Reference Ability Neural Network Study: motivation, design, and initial feasibility analyses. NeuroImage. 2014 Academic Article GET IT
Times cited: 69
RETROSPECTIVE DETECTION OF INTERLEAVED SLICE ACQUISITION PARAMETERS FROM FMRI DATA. Proceedings. IEEE International Symposium on Biomedical Imaging. 2014 Academic Article GET IT
The role of education and verbal abilities in altering the effect of age-related gray matter differences on cognition. PloS one. 2014 Academic Article GET IT
Times cited: 38
Spatial Mutual Information as Similarity Measure for 3-D Brain Image Registration. IEEE journal of translational engineering in health and medicine. 2014 Academic Article GET IT
Times cited: 9
A new algorithm for predicting time to disease endpoints in Alzheimer's disease patients. Journal of Alzheimer's disease : JAD. 2014 Academic Article GET IT
Times cited: 18
Unilateral disruptions in the default network with aging in native space. Brain and behavior. 2013 Academic Article GET IT
Times cited: 32
Evaluating Similarity Measures for Brain Image Registration. Journal of visual communication and image representation. 2013 Academic Article GET IT
Computation of image spatial entropy using quadrilateral Markov random field. IEEE transactions on image processing : a publication of the IEEE Signal Processing Society. 2009 Academic Article GET IT
Times cited: 34

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Research

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Funding awarded

Tau progression index (TPI): An individualized predictor of Alzheimer''s Disease trajectory based on subject-specific connectomes awarded by National Institute on Aging Principal Investigator 2024 - 2029
missing activity Principal Investigator 2020 - 2024

Brain fluid clearance and misfolded protein dynamics following traumatic brain injury awarded by National Institute on Aging Co-Investigator 2023 - 2028

New PET/CT System for Human and Non-human Primate Imaging awarded by National Institutes of Health, Office of the Director Key Personnel 2023 - 2025

Using a Health Disparity Research Framework to examine mechanisms linking Obstructive Sleep Apnea with higher Alzheimer''s disease risk in older Blacks/African-Americans awarded by National Institute of Mental Health Principal Investigator Subaward 2023 - 2028
Exploring Cognitive Aging Using Reference Ability Neural Networks (RANN) Principal Investigator Subaward 2021 - 2023
Are there ethnic differences in brain amyloid and tau in the seventh decade of life? (Disparities) Principal Investigator Subaward 2020 - 2023

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Background

education and training

Ph.D., University of Texas 2009
M.Sc., K.N.T. University of Technology (Iran) 2000
B.Sc., Tehran University (Iran) 1997

Contact

full name

Ray Razlighi

primary email

qrr4001@med.cornell.edu

VIVO Weill Cornell Medical College

Ray Razlighi Associate Professor of Neuroscience in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email