Shaykhiev, Renat

Publications

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selected publications

A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine. 2023 Academic Article GET IT
Times cited: 27
Unsupervised discovery of tissue architecture in multiplexed imaging. Nature methods. 2022 Academic Article GET IT
Airway Basal Cells in Chronic Obstructive Pulmonary Disease: A Continuum or a Dead End?. American journal of respiratory cell and molecular biology. 2021 Editorial Article GET IT
Times cited: 3
Basal-like Cells in the BAL Fluid: An Echo of Regenerative Crisis in Idiopathic Pulmonary Fibrosis Lungs. American journal of respiratory and critical care medicine. 2019 Comment GET IT
Times cited: 3
Emerging biology of persistent mucous cell hyperplasia in COPD. Thorax. 2018 Editorial Article GET IT
Times cited: 26
At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine. 2018 Academic Article GET IT
Times cited: 202
Update in Chronic Obstructive Pulmonary Disease 2017. American journal of respiratory and critical care medicine. 2018 Academic Article GET IT
Times cited: 4
Airway Epithelial Progenitors and the Natural History of Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine. 2018 Editorial Article GET IT
Times cited: 4
Reply: Epithelial-Mesenchymal Transition: A Necessary New Therapeutic Target in Chronic Obstructive Pulmonary Disease?. American journal of respiratory and critical care medicine. 2017 Comment GET IT
Smoking-Dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium. American journal of respiratory and critical care medicine. 2017 Academic Article GET IT
Times cited: 65
EGF-Amphiregulin Interplay in Airway Stem/Progenitor Cells Links the Pathogenesis of Smoking-Induced Lesions in the Human Airway Epithelium. Stem cells (Dayton, Ohio). 2016 Academic Article GET IT
Times cited: 50
Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers. American journal of respiratory and critical care medicine. 2016 Academic Article GET IT
Times cited: 25
POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes. Journal of immunology (Baltimore, Md. : 1950). 2016 Academic Article GET IT
Times cited: 42
Multitasking basal cells: combining stem cell and innate immune duties. The European respiratory journal. 2015 Editorial Article GET IT
Times cited: 14
Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. 2014 Article GET IT
Times cited: 85
Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2. PloS one. 2014 Academic Article GET IT
Times cited: 61
Basal cell origins of smoking-induced airway epithelial disorders. Cell cycle (Georgetown, Tex.). 2013 Editorial Article GET IT
Times cited: 20
Innate immunity and chronic obstructive pulmonary disease: a mini-review. Gerontology. 2013 Information Resource GET IT
Times cited: 64
Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer. Stem cells (Dayton, Ohio). 2013 Academic Article GET IT
Times cited: 28
Smoking-induced CXCL14 expression in the human airway epithelium links chronic obstructive pulmonary disease to lung cancer. American journal of respiratory cell and molecular biology. 2013 Academic Article GET IT
Times cited: 33
EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 82
Lung adenocarcinoma subtypes based on expression of human airway basal cell genes. The European respiratory journal. 2013 Academic Article GET IT
Times cited: 34
RNA-Seq quantification of the human small airway epithelium transcriptome. BMC genomics. 2012 Academic Article GET IT
Times cited: 96
The human airway epithelial basal cell transcriptome. PloS one. 2011 Academic Article GET IT
Times cited: 154
Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer. Cancer research. 2011 Academic Article GET IT
Times cited: 35
Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo. Cellular and molecular life sciences : CMLS. 2010 Academic Article GET IT
Times cited: 172
The antimicrobial peptide cathelicidin enhances activation of lung epithelial cells by LPS. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2010 Academic Article GET IT
Times cited: 36
Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome?. American journal of respiratory cell and molecular biology. 2010 Academic Article GET IT
Times cited: 129
Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 330
Microbial patterns signaling via Toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival. PloS one. 2008 Academic Article GET IT
Times cited: 75
The role of cathelicidin and defensins in pulmonary inflammatory diseases. Expert opinion on biological therapy. 2007 Review GET IT
Times cited: 93
The host defence peptide LL-37/hCAP-18 is a growth factor for lung cancer cells. Lung cancer (Amsterdam, Netherlands). 2007 Academic Article GET IT
Times cited: 138
Interactions between epithelial cells and leukocytes in immunity and tissue homeostasis. Journal of leukocyte biology. 2007 Review GET IT
Times cited: 78
The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands. International immunology. 2006 Academic Article GET IT
Times cited: 109
Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure. American journal of physiology. Lung cellular and molecular physiology. 2005 Academic Article GET IT
Times cited: 233

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Research

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Funding awarded

missing activity Principal Investigator 2019 - 2023

Understanding the Origins of Early COPD awarded by National Heart, Lung, & Blood Institute Co-Investigator 2020 - 2025

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Background

education and training

Ph.D., Philipps University, Marburg (Germany) 2007
M.D., Kazan State Medical University (Russia) 2000

Contact

full name

Renat Shaykhiev

primary email

res2003@med.cornell.edu

VIVO Weill Cornell Medical College

Renat Shaykhiev Associate Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email